anti-PDGFRB (PDGFRB) Antikörper

Bezeichnung:
anti-Platelet-Derived Growth Factor Receptor, beta Polypeptide Antikörper (PDGFRB)
Auf www.antikoerper-online.de finden Sie aktuell 587 Platelet-Derived Growth Factor Receptor, beta Polypeptide (PDGFRB) Antikörper von 32 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen PDGFRB Kits (44) und PDGFRB Proteine (41) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 714 PDGFRB Produkte verfügbar.
Synonyme:
AI528809, CD140B, IBGC4, JTK12, PDGFR, PDGFR-1, PDGFR1

Alle verfügbaren anti-PDGFRB Antikörper

Sie gelangen zu unserer vorgefilterten Suche.

Am meisten referenzierte anti-PDGFRB Antikörper

  1. Human Monoclonal PDGFRB Primary Antibody für IF, IHC (p) - ABIN111188 : Hart, Seifert, Ross, Bowen-Pope: Synthesis, phosphorylation, and degradation of multiple forms of the platelet-derived growth factor receptor studied using a monoclonal antibody. in The Journal of biological chemistry 1987 (PubMed)
    Zeige alle 3 Referenzen für 111188

  2. Human Monoclonal PDGFRB Primary Antibody für IHC (f), WB - ABIN967593 : Claesson-Welsh: Platelet-derived growth factor receptor signals. in The Journal of biological chemistry 1995 (PubMed)
    Zeige alle 3 Referenzen für 967593

  3. Human Polyclonal PDGFRB Primary Antibody für EIA, IHC (p) - ABIN359922 : Wu, Windmiller, Wang, Backer: YXXM motifs in the PDGF-beta receptor serve dual roles as phosphoinositide 3-kinase binding motifs and tyrosine-based endocytic sorting signals. in The Journal of biological chemistry 2003 (PubMed)
    Zeige alle 3 Referenzen für 359922

  4. Human Polyclonal PDGFRB Primary Antibody für ELISA, WB - ABIN1532640 : Chi, McPhee, Wagner, Dietz, Pantazis, Goustin: Integration of proviral DNA into the PDGF beta-receptor gene in HTLV-I-infected T-cells results in a novel tyrosine kinase product with transforming activity. in Oncogene 1997 (PubMed)

  5. Human Polyclonal PDGFRB Primary Antibody für IF, IHC - ABIN1532388 : Wilkinson, Velloso, Lopes, Lee, Aster, Shipp, Aguiar: Cloning of the t(1;5)(q23;q33) in a myeloproliferative disorder associated with eosinophilia: involvement of PDGFRB and response to imatinib. in Blood 2003 (PubMed)

  6. Human Polyclonal PDGFRB Primary Antibody für IF, IHC - ABIN1532980 : Yu, Zeidel, Hill: Cellular expression profile for interstitial cells of cajal in bladder - a cell often misidentified as myocyte or myofibroblast. in PLoS ONE 2012 (PubMed)

Weitere Antikörper gegen PDGFRB Interaktionspartner

Mouse (Murine) Platelet-Derived Growth Factor Receptor, beta Polypeptide (PDGFRB) Interaktionspartner

  1. Identify PDGFRbeta as a driver in activating Akt (zeige AKT1 Antikörper)/mTORC1 nexus for high glucose-mediated expression of collagen I (alpha2) in proximal tubular epithelial cells, which contributes to tubulointerstitial fibrosis in diabetic nephropathy.

  2. Data show that three platelet-derived growth factor receptor beta (PDGFRB) mutants (R561C, P660T and N666K) were able to transform NIH3T3 and Ba/F3 cells to different extents.

  3. data therefore collectively suggest that upon TGFbeta (zeige TGFB1 Antikörper) stimulation, SP1 (zeige SP1 Antikörper) recruits SMAD2 (zeige SMAD2 Antikörper) to the promoter of Pdgfrb to up-regulate its expression and thus Pdgfrb is a direct downstream target of the TGFbeta (zeige TGFB1 Antikörper)/SMAD2 (zeige SMAD2 Antikörper) signaling

  4. PdgfrbetaF7/F7 mice between 4-6 and 36-48 weeks of age developed a region-dependent loss in pericyte coverage (22-46, 24-44 and 4-31%) and cell numbers (36-49, 34-64 and 11-36%), reduction in capillary length (20-39, 13-46 and 1-30%), and an increase in extravascular fibrinogen-derived deposits (3.4-5.2, 2.8-4.1 and 0-3.6-fold) demonstrating BBB (zeige ALMS1 Antikörper) breakdown in the cortex, hippocampus and thalamus, respectively.

  5. PDGF-B (zeige PDGFB Antikörper)-PDGFRbeta signaling plays a significant role in the development of adipose tissue neovascularization.

  6. there is great possibility that EPCs overexpressing PDGFR-beta enhanc VSMC apoptosis and suppress VSMC migration by competitive consumption of PDGF (zeige PDGFA Antikörper)-BB in the early phase after carotid artery injury in mice.

  7. PDGFRalpha and PDGFRbeta are coexpressed in the craniofacial mesenchyme of mid-gestation mouse embryos and that ablation of Pdgfrb in the neural crest lineage results in increased nasal septum width, delayed palatal shelf development, and subepidermal blebbing.

  8. The results from this study indicate that PDGF (zeige PDGFA Antikörper) signaling is required for fiber hypertrophy, extracellular matrix production, and angiogenesis that occur during muscle growth.

  9. Data show that oligodendrocyte transcription factor 2 (Olig2 (zeige OLIG2 Antikörper)) deletion causes platelet-derived growth factor receptor (PDGFR) downregulation and reciprocal epidermal growth factor receptor (EGFR (zeige EGFR Antikörper)) upregulation.

  10. Decreased expression of PDGFR-beta in vascular smooth muscle cells was associated with thrombosis in vivo.

Human Platelet-Derived Growth Factor Receptor, beta Polypeptide (PDGFRB) Interaktionspartner

  1. Identify PDGFRbeta as a driver in activating Akt (zeige AKT1 Antikörper)/mTORC1 nexus for high glucose-mediated expression of collagen I (alpha2) in proximal tubular epithelial cells, which contributes to tubulointerstitial fibrosis in diabetic nephropathy.

  2. Higher expression of PDGFR-Beta is related to more serious dural penetration of clival chordomas.

  3. Targeted next-generation DNA sequencing identified PDGFRB alterations in all cases of myopericytomatosis and conventional myopericytoma tested (5 cases each), including mutations in 4 cases of myopericytomatosis (N666K in 3; Y562-R565 deletion in 1 case) and 3 myopericytomas (Y562C, K653E, and splice acceptor deletion in 1 case each), as well as low-level PDGFRB amplification in 2 cases of myopericytomatosis and 4 myoperi

  4. Elevated PDGFRB expression was noted in 20.7% of patients with papillary renal cell carcinoma (zeige MOK Antikörper).

  5. Imatinib in myeloid/lymphoid neoplasms with eosinophilia and rearrangement of PDGFRB in chronic or blast phase

  6. inhibition of any internalization mechanism impaired activation of STAT3 (zeige STAT3 Antikörper) but not of other downstream effectors of PDGFRbeta.

  7. this is the first study reporting apparently somatic recurrent PDGFRB mutations as molecular driver events in the majority of sporadic infantile and adult solitary myofibromas

  8. results demonstrate that miR (zeige MLXIP Antikörper)-9 and miR (zeige MLXIP Antikörper)-200 play opposite roles in the regulation of the vasculogenic ability of triple-negative breast cancer, acting as facilitator and suppressor of PDGFRbeta, respectively

  9. Among 15 childhood ALL patients with EBF1 (zeige EBF1 Antikörper)-PDGFRB fusion proteins, the fusion arose from interstitial deletion of 5q33 (n = 11), balanced rearrangement (n = 2), or complex rearrangement (n = 2).

  10. Previously unrecognised associations between renal cell carcinoma (zeige MOK Antikörper) survival and the absolute levels, and variability, of perivascular PDGFR-beta.

PDGFRB Antigen-Profil

Beschreibung des Gens

This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor\; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia.

Alternative names and synonyms associated with PDGFRB

  • platelet derived growth factor receptor, beta polypeptide (Pdgfrb) Antikörper
  • platelet-derived growth factor receptor, beta polypeptide (PDGFRB) Antikörper
  • AI528809 Antikörper
  • CD140B Antikörper
  • IBGC4 Antikörper
  • JTK12 Antikörper
  • PDGFR Antikörper
  • PDGFR-1 Antikörper
  • PDGFR1 Antikörper

Bezeichner auf Proteinebene für PDGFRB

CD140 antigen-like family member B , PDGF beta chain , PDGF-R-beta , PDGFR-beta , beta platelet-derived growth factor receptor , beta-type platelet-derived growth factor receptor , platelet-derived growth factor receptor 1 , platelet-derived growth factor receptor beta , platelet-derived growth factor receptor beta variant 1 , Platelet-derived growth factor receptor, beta , protein tyrosin kinase

GENE ID SPEZIES
18596 Mus musculus
24629 Rattus norvegicus
5159 Homo sapiens
442985 Canis lupus familiaris
770488 Gallus gallus
100342872 Oryctolagus cuniculus
Ausgewählte Anbieter für anti-PDGFRB (PDGFRB) Antikörper
Haben Sie etwas anderes gesucht?