Use your antibodies-online credentials, if available.
Keine Produkte auf Ihrer Vergleichsliste.
Ihr Warenkorb ist leer.
Alle Spezies anzeigen
Weitere Synonyme anzeigen
Wählen Sie die Spezies und Applikation aus
anti-Mouse (Murine) Antikörper:
anti-Rat (Rattus) Antikörper:
Sie gelangen zu unserer vorgefilterten Suche.
Human Polyclonal KL Primary Antibody für FACS, WB - ABIN389493
Sugiyama, Masuda, Shinoda, Nakamura, Tomita, Ishihama: Phosphopeptide enrichment by aliphatic hydroxy acid-modified metal oxide chromatography for nano-LC-MS/MS in proteomics applications. in Molecular & cellular proteomics : MCP 2007
Show all 2 Pubmed References
Human Polyclonal KL Primary Antibody für IHC (p), IHC - ABIN250843
Kurosu, Yamamoto, Clark, Pastor, Nandi, Gurnani, McGuinness, Chikuda, Yamaguchi, Kawaguchi, Shimomura, Takayama, Herz, Kahn, Rosenblatt, Kuro-o: Suppression of aging in mice by the hormone Klotho. in Science (New York, N.Y.) 2005
Human Polyclonal KL Primary Antibody für ELISA, ICC - ABIN4329242
Manrique, Habibi, Aroor, Sowers, Jia, Hayden, Garro, Martinez-Lemus, Ramirez-Perez, Klein, Meininger, DeMarco: Dipeptidyl peptidase-4 inhibition with linagliptin prevents western diet-induced vascular abnormalities in female mice. in Cardiovascular diabetology 2016
Human Polyclonal KL Primary Antibody für WB - ABIN4890528
Chen, Gould, Garza, Gao, Hampton, Newton: Amplitude control of protein kinase C by RINCK, a novel E3 ubiquitin ligase. in The Journal of biological chemistry 2007
Human Polyclonal KL Primary Antibody für ELISA - ABIN450061
Chen, Podvin, Gillespie, Leeman, Abraham: Insulin stimulates the cleavage and release of the extracellular domain of Klotho by ADAM10 and ADAM17. in Proceedings of the National Academy of Sciences of the United States of America 2007
Review of Klotho function and dysfunction in mice and humans. [Review Article]
The Klotho KL-VS variant is associated with an increase in the incidence of dementia in older men, in a dose-dependent fashion (intermediate for heterozygosis and highest for homozygosis).
Our findings provide the first evidence that alpha-Klotho is significantly decreased in the microvasculature in systemic sclerosis skin
indicates an inverse interrelationship between inflammation and Klotho in atherosclerosis
Administration of soluble klotho significantly reduced obstruction-induced renal fibrosis in wild-type mice, but not in Trpc6 (zeige TRPC6 Antikörper) knockout mice, indicating that klotho and TRPC6 (zeige TRPC6 Antikörper) inhibition act in the same pathway to protect against obstruction-induced renal fibrosis.
The role of Klotho protein in aging and central nervous system pathology is reviewed.
These results support the notion that sialogangliosides and lipid rafts are membrane receptors for sKlotho and that the KL1 (zeige KITLG Antikörper) domain is sufficient for the tested biologic activities.
Klotho is expressed in human dermal fibroblasts and dermal microvascular endothelial cells and is implicated in the process of angiogenesis.
Sclerostin (zeige SOST Antikörper) levels in KTR are normal and influenced more by bone turnover than by eGFR (zeige EGFR Antikörper). Its involvement with other hormones of mineral homeostasis (FGF23 (zeige FGF23 Antikörper)/Klotho and Vitamin D) is part of the sophisticated cross-talk between bone and the kidney
Results showed that human endothelial cells differentially express functional full-length alpha-Klotho protein. And that it is this full-length alpha-Klotho protein that modulates endothelial cells response to FGF-23 (zeige FGF23 Antikörper).
Overexpression of Klotho inhibits the differentiation of RAW264.7 cells into osteoclasts.
Data suggest that klotho affects cognition, at least in part, by regulating hippocampal synaptic plasticity.
Adiponectin alters calcium and phosphate balance and renal mineral excretion, in part, through klotho.
Klotho in bone is crucial for inducing FGF23 (zeige FGF23 Antikörper) production upon renal failure
Results are the first to suggest an integrated regulatory function of Klotho in the distal and proximal tubules on mineral metabolism.
Data show that Klotho protein is present in the heart, and reduced levels of myocardial Klotho in aging mice is accompanied by lower levels heat shock protein 70 (HSP70 (zeige HSP70 Antikörper)) in the myocardium.
Klotho preserves AEC mtDNA integrity in the setting of oxidative stress necessary for preventing apoptosis and asbestos-induced lung fibrosis.
epigenetic silencing of klotho during muscular dystrophy contributes substantially to lost regenerative capacity and increased fibrosis of dystrophic muscle during late progressive stages of the disease.
Klotho gene deficiency promotes high-fat diet-induced fibrosis in aortic valves, likely through the AMPKalpha (zeige GRK4 Antikörper)-RUNX2 (zeige RUNX2 Antikörper) pathway.
significant expression of FGF23 (zeige FGF23 Antikörper) and KL within the growth plate and adjacent tissues imply a potential local role of FGF23 (zeige FGF23 Antikörper) in chondrocyte differentiation and tissue mineralization.
This gene encodes a type-I membrane protein that is related to beta-glucosidases. Reduced production of this protein has been observed in patients with chronic renal failure (CRF), and this may be one of the factors underlying the degenerative processes (e.g., arteriosclerosis, osteoporosis, and skin atrophy) seen in CRF. Also, mutations within this protein have been associated with ageing and bone loss.
, kit ligand
, secreted form of Klotho protein