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Human Polyclonal TFF1 Primary Antibody für IHC, IHC (p) - ABIN4358634
Pontén, Jirström, Uhlen: The Human Protein Atlas--a tool for pathology. in The Journal of pathology 2008
Show all 4 Pubmed References
Human Monoclonal TFF1 Primary Antibody für ELISA, WB - ABIN563163
Iorns, Martens-de Kemp, Lord, Ashworth: CRK7 modifies the MAPK pathway and influences the response to endocrine therapy. in Carcinogenesis 2009
Human Monoclonal TFF1 Primary Antibody für ELISA, WB - ABIN563164
Kam, Hennessy, Chua, Gan, Philp, Hon, Lai, Chan, Ong, Wong, Lim, Ling, Tan, Tan, Ho, Kon: Characterization of the human gastric fluid proteome reveals distinct pH-dependent protein profiles: implications for biomarker studies. in Journal of proteome research 2011
expression of xP1-L was detected in stage 41/42 tadpoles; in situ hybridization showed that xP1-L was localized to surface mucous cells of the larval stomach
Low TFF1 expression is associated with retinoblastoma.
The results suggest that the analysis of expression of MUC5AC and TFF1 may be useful for differentiating sessile serrated adenomas/polyps (SSA (zeige TRIM21 Antikörper)/Ps) from hyperplastic polyps (HPs (zeige HPS1 Antikörper)).
TFF1 displays a distinct protein expression pattern in the developing of airway remodeling due to Sulfur mustard inhalation and plays an important role in maintaining the airway epithelium function
we found TFF1 plays an oncogenic role in mucinous ovarian cancer
These results show increased levels of TFF1 and TFF3 (zeige TFF3 Antikörper) in Chronic Kidney Disease patients with a pronounced elevation of urinary TFF1 in lower Chronic Kidney Disease stages.
Loss of TFF1 could be a critical step in promoting the H. pylori-mediated oncogenic activation of beta-catenin (zeige CTNNB1 Antikörper) and gastric tumorigenesis.
We have established a novel, three-protein biomarker panel that is able to detect patients with early-stage pancreatic cancer in urine specimens:LYVE-1, REG1A (zeige REG1A Antikörper), and TFF1 were selected as candidate biomarkers
These findings suggest that the rs184432 and rs225359 polymorphisms in TFF1 have protective effects for GC and contribute to the development of GC in Korean individuals.
Findings underscore an important protective role of TFF1 in abrogating H. pylori-mediated inflammation, a crucial hallmark of gastric tumorigenesis. Loss of TFF1 expression could be an important step in H. pylori-mediated gastric carcinogenesis.
trefoil factor 1 demonstrated breast specificity but was inferior to mammaglobin and GATA protein binding 3
the Tg(Tff1-CreERT2;Tff2 (zeige TFF2 Antikörper)-rtTA;Tff3 (zeige TFF3 Antikörper)-Luc) strain can confer intermittent transgene expression to gastric epithelial cells that have undergone previous gene modification, and may be suitable to genetically model therapeutic intervention during development, tumorigenesis, and other genetically tractable diseases
The up-regulated expression of Tff1 is probably the result of a complex inflammatory process as its expression is induced by tumor necrosis factor alpha (zeige TNF Antikörper) as well as interleukins 1beta and 17.
TFF1 and TFF3 (zeige TFF3 Antikörper) peptides might be involved in the complex processes of nervous system development and differentiation and brain plasticity.
Loss of TFF1 promotes beta-catenin (zeige CTNNB1 Antikörper) activation and gastric tumorigenesis through regulation of PP2A (zeige PPP2R2B Antikörper), a major regulator AKT (zeige AKT1 Antikörper)-GSK3Beta (zeige GSK3b Antikörper) signaling.
Loss of Tff1 and high expression of cox2 (zeige COX2 Antikörper) are associated with gastric adenomas.
increased oncogenic potential of MCF7 cells in the absence of TFF1 was confirmed in vivo in nude mice
loss of TFF1 leads to activation of IKK (zeige CHUK Antikörper) complex-regulated NF-kappaB (zeige NFKB1 Antikörper) transcription factors and is an important event in shaping the NF-kappaB (zeige NFKB1 Antikörper)-mediated inflammatory response during the progression to gastric tumorigenesis
Initiation of antral gastric cancer is associated with progressive epigenetic silencing of TFF1, which can be suppressed by the hormone gastrin (zeige GAST Antikörper).
Colon from infected swine had increased expression of MUC5AC and TFF1 relative to controls.
Weaning was not associated with fifferential TFF1 expression in the distal jejunum and ileum.
Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer, and affect healing of the epithelium. This gene, which is expressed in the gastric mucosa, has also been studied because of its expression in human tumors. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21.
trefoil factor 1
, P-domain peptide
, trefoil factor family peptide 1
, breast cancer estrogen-inducible protein
, breast cancer estrogen-inducible sequence
, gastrointestinal trefoil protein pS2
, polypeptide P1.A
, protein pS2
, trefoil factor 1 (breast cancer, estrogen-inducible sequence expressed in)
, P-domain peptide pS2 gene product homolog
, putative gastrointestinal growth factor xP1