anti-PTK2B (PTK2B) Antikörper

Bezeichnung:
anti-PTK2B Protein tyrosine Kinase 2 beta Antikörper (PTK2B)
Auf www.antikoerper-online.de finden Sie aktuell 257 PTK2B Protein tyrosine Kinase 2 beta (PTK2B) Antikörper von 25 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen PTK2B Kits (21) und PTK2B Proteine (14) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 310 PTK2B Produkte verfügbar.
Synonyme:
Akt, CADTK, CAKB, CAKbeta, E430023O05Rik, FADK2, FAK2, PKB, PKB/Akt, PKBalpha, PTK, Pyk2, Rac, Raftk

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Am meisten referenzierte anti-PTK2B Antikörper

  1. Human Polyclonal PTK2B Primary Antibody für IF, IHC (p) - ABIN196952 : Gluck: Acid sensing in renal epithelial cells. in The Journal of clinical investigation 2004 (PubMed)
    Zeige alle 5 Referenzen für 196952

  2. Human Monoclonal PTK2B Primary Antibody für IHC, ELISA - ABIN1724705 : Dylla, Deyle, Theunissen, Padurean, Verfaillie: Integrin engagement-induced inhibition of human myelopoiesis is mediated by proline-rich tyrosine kinase 2 gene products. in Experimental hematology 2004 (PubMed)
    Zeige alle 3 Referenzen für 1724705

  3. Human Polyclonal PTK2B Primary Antibody für ELISA, WB - ABIN1533144 : Lev, Moreno, Martinez, Canoll, Peles, Musacchio, Plowman, Rudy, Schlessinger: Protein tyrosine kinase PYK2 involved in Ca(2+)-induced regulation of ion channel and MAP kinase functions. in Nature 1995 (PubMed)
    Zeige alle 2 Referenzen für 1533144

  4. Human Polyclonal PTK2B Primary Antibody für IHC, ELISA - ABIN1532112 : Herzog, Nicholl, Hort, Sutherland, Shine: Molecular cloning and assignment of FAK2, a novel human focal adhesion kinase, to 8p11.2-p22 by nonisotopic in situ hybridization. in Genomics 1997 (PubMed)
    Zeige alle 2 Referenzen für 1532112

  5. Human Polyclonal PTK2B Primary Antibody für IF, IHC (p) - ABIN197440 : Benzing, Gerke, Höpker, Hildebrandt, Kim, Walz: Nephrocystin interacts with Pyk2, p130(Cas), and tensin and triggers phosphorylation of Pyk2. in Proceedings of the National Academy of Sciences of the United States of America 2001 (PubMed)
    Zeige alle 2 Referenzen für 197440

  6. Human Polyclonal PTK2B Primary Antibody für IF (p), IHC (p) - ABIN745763 : Cao, Zheng, Wang, Wang, Li, Li, Lai, Wang, Qin: Src blockage by siRNA inhibits VEGF-induced vascular hyperpemeability and osteoclast activity - an in vitro mechanism study for preventing destructive repair of osteonecrosis. in Bone 2015 (PubMed)

  7. Cow (Bovine) Polyclonal PTK2B Primary Antibody für WB - ABIN2779800 : Ling, Sheng, Braun: The calcium-dependent activity of large-conductance, calcium-activated K+ channels is enhanced by Pyk2- and Hck-induced tyrosine phosphorylation. in American journal of physiology. Cell physiology 2004 (PubMed)

  8. Human Polyclonal PTK2B Primary Antibody für ICC, IF - ABIN257536 : Lu, Chen, Shimoda, Park, Zhang, Tran, Zhang, Semenza: Chemotherapy-Induced Ca(2+) Release Stimulates Breast Cancer Stem Cell Enrichment. in Cell reports 2017 (PubMed)

Weitere Antikörper gegen PTK2B Interaktionspartner

Mouse (Murine) PTK2B Protein tyrosine Kinase 2 beta (PTK2B) Interaktionspartner

  1. TSC1 (zeige TSC1 Antikörper)/TSC2 (zeige TSC2 Antikörper) complex upregulation of OPN (zeige SPP1 Antikörper) expression is mediated by transcription factor SOX9 (zeige SOX9 Antikörper) in an mTOR (zeige FRAP1 Antikörper)-independent manner. Moreover, ablation of OPN (zeige SPP1 Antikörper) by deficient TSC1 (zeige TSC1 Antikörper)/TSC2 (zeige TSC2 Antikörper) complex contributed to inactivation of AKT (zeige AKT1 Antikörper) in TSC (zeige SLC12A3 Antikörper) cells

  2. Our results suggest that increasing Akt (zeige AKT1 Antikörper)/ NF-kappaB (zeige NFKB1 Antikörper) is a crucial mediator of skin aging, which can increase the susceptibility of cell transformation.

  3. findings highlight a pivotal link between an epigenetic regulator, WHSC1, and key intracellular signaling molecules, AKT, RICTOR, and Rac1, to drive prostate cancer metastasis.

  4. Studies indicate that the Pten (zeige PTEN Antikörper)+/- genotype displayed neoplasia in multiple organs, including the endometrium and that the Pten (zeige PTEN Antikörper) is a key regulatory player in the PI3K/PTEN (zeige PTEN Antikörper)/AKT (zeige AKT1 Antikörper) pathway.

  5. a simple, linear, four-compartment ordinary differential equation (ODE) model of Akt (zeige AKT1 Antikörper) activation that tracks both the biochemical state and the physical location of Akt (zeige AKT1 Antikörper), is reported.

  6. Psgl-1 (zeige SELPLG Antikörper) deficiency accelerates bleomycin-induced lung fibrosis and inflammation in mice through activating the PI3K/AKT (zeige AKT1 Antikörper) axis.

  7. Data show that docetaxel, rapamycin and tanespimycin multi-drug loaded micelles targeted against HSP90 (zeige HSP90 Antikörper) and the PI3K/AKT (zeige AKT1 Antikörper)/mTOR (zeige FRAP1 Antikörper) pathway in prostate cancer.

  8. results show that Pyk2 contributes to cytotoxic T lymphocyte(CTL) migration by regulating detachment of CTL at the trailing edge, which could explain why Pyk2 is important for chemotactic and migratory responses.

  9. Furthermore, Leishmania RNA virus 1-induced TLR-3 (zeige TLR3 Antikörper) activation promoted parasite persistence by enhancing macrophage survival through Akt (zeige AKT1 Antikörper) activation in a manner partially dependent on miR (zeige MLXIP Antikörper)-155.

  10. Collectively, these findings showed that SA suppressed mammary gland development of pubertal mice, which was coincident with the SA-inhibited HC11 (zeige CCL2 Antikörper) proliferation, and was associated with inhibition of PI3K/Akt (zeige AKT1 Antikörper) signaling pathway through activation of GPR120 (zeige O3FAR1 Antikörper).

Human PTK2B Protein tyrosine Kinase 2 beta (PTK2B) Interaktionspartner

  1. Our findings suggest that Pyk2 plays an important role in the coordination of stabilization of beta-catenin (zeige CTNNB1 Antikörper) in the crosstalk between Wnt (zeige WNT2 Antikörper)/beta-catenin (zeige CTNNB1 Antikörper) and Wnt (zeige WNT2 Antikörper)/Ca(2 (zeige CA2 Antikörper)+) signaling pathways upon Wnt3a (zeige WNT3A Antikörper) stimulation in differentiating hNPCs.

  2. STIM1 (zeige STIM1 Antikörper)-induced Ca(2 (zeige CA2 Antikörper)+) signaling activates Pyk2 to inhibit the interaction of VE-PTP (zeige PTPRB Antikörper) and VE-cadherin (zeige CDH5 Antikörper) and hence increase endothelial permeability.

  3. Ascites and CCL18 (zeige CCL18 Antikörper) stimulate the phosphorylation and expression of Pyk2, which positively regulates ascites-induced ovarian cancer cell migration.

  4. We demonstrated trophoblast cytoprotection by intervention with supraphysiological concentrations of relaxin, a process in part mediated through the PI3-kinase (zeige PIK3CA Antikörper)-Akt/PKB (zeige AKT1 Antikörper) cell survival pathway. These results provide further rationale for clinical investigation of relaxin as a potential therapeutic in preeclampsia.

  5. PTK2B polymorphism (rs28834970) could modify the risk of late-onset Alzheimer's disease (LOAD), and PTK2B polymorphism (rs28834970) and APOE may interact to increase LOAD risk in a Han Chinese population.

  6. Studies suggest that PYK2 is a common downstream effector of ErbB (zeige EGFR Antikörper) and IL8 (zeige IL8 Antikörper) receptors, and that PYK2 integrates their signaling pathways through a positive feedback loop to potentiate breast cancer invasion.

  7. Pyk2 is a key downstream signaling molecules of CCR7 (zeige CCR7 Antikörper) in SCCHN, which promotes SCCHN tumorigenesis and progression.

  8. Phosphoproteomic analysis identifies FAK2 as a potential therapeutic target for tamoxifen resistance in breast cancer.

  9. Pyk2-focal adhesion targeting domain interacts with and binds to leupaxin (zeige LPXN Antikörper).

  10. Src (zeige SRC Antikörper) has a role in priming Pyk2 (but not FAK (zeige PTK2 Antikörper)) phosphorylation and subsequent activation downstream of integrins

Cow (Bovine) PTK2B Protein tyrosine Kinase 2 beta (PTK2B) Interaktionspartner

  1. Ptk2b activation may play a key role in the signaling responses in ECs under hemodynamic influence [proline-rich tyrosine kinase 2]

PTK2B Antigen-Profil

Beschreibung des Gens

This gene encodes a cytoplasmic protein tyrosine kinase which is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway. The encoded protein may represent an important signaling intermediate between neuropeptide-activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. The encoded protein undergoes rapid tyrosine phosphorylation and activation in response to increases in the intracellular calcium concentration, nicotinic acetylcholine receptor activation, membrane depolarization, or protein kinase C activation. This protein has been shown to bind CRK-associated substrate, nephrocystin, GTPase regulator associated with FAK, and the SH2 domain of GRB2. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Four transcript variants encoding two different isoforms have been found for this gene.

Alternative names and synonyms associated with PTK2B

  • v-akt murine thymoma viral oncogene homolog 1 (Akt1) Antikörper
  • thymoma viral proto-oncogene 1 (Akt1) Antikörper
  • protein tyrosine kinase 2 beta (PTK2B) Antikörper
  • protein tyrosine kinase 2 beta (Ptk2b) Antikörper
  • PTK2 protein tyrosine kinase 2 beta (Ptk2b) Antikörper
  • PTK2B protein tyrosine kinase 2 beta (PTK2B) Antikörper
  • Akt Antikörper
  • CADTK Antikörper
  • CAKB Antikörper
  • CAKbeta Antikörper
  • E430023O05Rik Antikörper
  • FADK2 Antikörper
  • FAK2 Antikörper
  • PKB Antikörper
  • PKB/Akt Antikörper
  • PKBalpha Antikörper
  • PTK Antikörper
  • Pyk2 Antikörper
  • Rac Antikörper
  • Raftk Antikörper

Bezeichner auf Proteinebene für PTK2B

AKT1 kinase , PKB alpha , RAC protein kinase alpha RAC-PK alpha , RAC-PK-alpha , RAC-alpha serine/threonine-protein kinase , murine thymoma viral (v-akt) oncogene homolog 1 , protein kinase B alpha , thymoma viral proto-oncogene 1 , protein kinase B-alpha , proto-oncogene c-AKT , related to A and C kinases , CAK-beta , FADK 2 , PTK2B protein tyrosine kinase 2 beta , calcium-dependent tyrosine kinase , calcium-regulated non-receptor proline-rich tyrosine kinase , cell adhesion kinase beta , focal adhesion kinase 2 , proline-rich tyrosine kinase 2 , protein kinase B , protein-tyrosine kinase 2-beta , related adhesion focal tyrosine kinase , CADTK , CAK beta , PTK2 protein tyrosine kinase 2 beta , cellular adhesion kinase beta , protein tyrosine kinase 2 beta

GENE ID SPEZIES
24185 Rattus norvegicus
11651 Mus musculus
2185 Homo sapiens
50646 Rattus norvegicus
19229 Mus musculus
486102 Canis lupus familiaris
541008 Bos taurus
421998 Gallus gallus
100157507 Sus scrofa
100342358 Oryctolagus cuniculus
Ausgewählte Anbieter für anti-PTK2B (PTK2B) Antikörper
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