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Human Mesothelin ELISA Kit für Sandwich ELISA - ABIN423233
Bostanc?, Kemik, Kemik, Battal, Demir, Purisa, Yavuz, Mihmanl?: Preoperative serum levels of mesothelin in patients with colon cancer. in Disease markers 2014
Mesothelin/mucin 16 (zeige MUC16 ELISA Kits) signaling in activated portal fibroblasts regulates cholestatic liver fibrosis.(
MiR (zeige MLXIP ELISA Kits)-21-5p is suggested as novel regulator of MSLN with a possible functional role in cellular growth.
we report herein that high tumor mesothelin expression predicts a shorter PFS and OS in EOC patients and demonstrates that serum mesothelin predicts local tumor mesothelin expression.
We provide new evidence for the role of MSLN in EMT (zeige ITK ELISA Kits) regulation, tumorigenesis and metastasis. Knockdown of MSLN led to mesenchymal to epithelial transition and less aggressive behavior of lung carcinoma and mesothelioma cells.
MSLN expression increases cell migration and invasion in vitro.
SMRP (zeige ABCC5 ELISA Kits) but not FBLN3 (zeige FBLN3 ELISA Kits) has a role in pleural effusions in in malignant pleural mesothelioma
High mesothelin expression is associated with malignant pleural mesothelioma.
Calretinin (zeige CALB2 ELISA Kits), D2-40 and mesothelin are aberrantly expressed in a proportion of CRC (zeige CALR ELISA Kits) cases.
Our results showed that IMP3 (zeige IGF2BP3 ELISA Kits) immunostaining has a higher sensitivity and specificity than mesothelin for the diagnosis of pancreatic ductal adenocarcinoma. IMP3 (zeige IGF2BP3 ELISA Kits) and mesothelin may be useful markers in distinguishing neoplastic from reactive lesions of the pancreas in instances where this is impossible by morphology alone in surgical pathology practice.
Results indicate a specific mesothelin-driven tumor uptake of targeted 89zirconium-labeled antibody which visualizes mesothelin expressing pancreatic cancer in real time.
this study revealed a role for GPER (zeige GPER ELISA Kits) activity in regulating Nox1 (zeige NOX1 ELISA Kits) abundance and associated O2(-)-mediated structural and functional damage that contributes to disease pathology
These findings provide strong evidence for aldosterone serving a causal role in renal cell cancer regulation via its GPER (zeige GPER ELISA Kits) receptor; thus, antagonism of GPER (zeige GPER ELISA Kits) represents a potential new target for treatment to reduce metastatic spread.
GPER (zeige GPER ELISA Kits) protects against hepatic tumorigenesis by regulating inflammatory responses.
Data suggest that prenatal exposure to p,p'-DDT (zeige DDT ELISA Kits) (an endocrine disrupting pesticide) causes sex- and age-independent attenuation of Gper1 in brain which appears to play key role in propagation of DDT (zeige DDT ELISA Kits)-induced depressive-like neurotoxicity.
Study suggested that the neuroprotective effect of estrogen requires intact GPER1-associated signaling in an in vitro model of ischemia. The membrane-associated signaling mediates the estrogen actions, and depends on PI3K/Akt (zeige AKT1 ELISA Kits) signaling for Ask1 (zeige MAP3K5 ELISA Kits) inhibition that prevents the cell death triggered by ischemia. These mechanisms may help for a therapeutic strategy to target on GPER1 for the treatment of neurological disorders.
Phosphorylation of myosin regulatory light chain triggered by E2 was found to be mediated by estrogen receptor-beta (zeige ESR2 ELISA Kits) and the G protein-coupled estrogen receptor (zeige ESR1 ELISA Kits).
Our study demonstrated the ameliorative role of GPR30 (zeige GPER ELISA Kits) in NOR memory impaired by AD pathology in female mice
identified a novel regulatory mechanism through which the endogenous Gper (zeige GPER ELISA Kits) facilitates the age-dependent increase in myocardial expression of ECE-2 (zeige ECE2 ELISA Kits) and the ETB (zeige EDNRB ELISA Kits) receptor, which is compatible with an activating role of GPER (zeige GPER ELISA Kits) for the local endothelin system with aging
We suggest that activation of GPER (zeige GPER ELISA Kits) exerts an inhibitory effect on colonic motility by promoting nitric oxide release from myenteric nitrergic nerves
This gene encodes a precursor protein that is cleaved into two products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiation factor functions as a cytokine that can stimulate colony formation in bone marrow megakaryocytes. Mesothelian is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants.
, megakaryocyte potentiating factor
, pre-pro-megakaryocyte-potentiating factor
, soluble MPF mesothelin related protein
, G protein-coupled receptor 30
, G-protein coupled estrogen receptor 1
, G-protein coupled receptor 30
, chemoattractant receptor-like 2
, constitutively expressed peptide-like receptor like
, membrane estrogen receptor
, protein expressed in renal carcinoma