ADCY3 Proteine (ADCY3)

Bezeichnung:
Adenylate Cyclase 3 Proteine (ADCY3)
Auf www.antikoerper-online.de finden Sie aktuell 10 Adenylate Cyclase 3 (ADCY3) Proteine von 5 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen ADCY3 Antikörper (26) und ADCY3 Kits (18) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 56 ADCY3 Produkte verfügbar.
Synonyme:
AC3, ADCY3, ADCY8, Amac3, GB11637, mKIAA0511, si:ch211-153j24.5
alle Proteine anzeigen Gen GeneID UniProt
ADCY3 109 O60266
ADCY3 104111 Q8VHH7
ADCY3 64508 P21932

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Weitere Proteine zu ADCY3 Interaktionspartnern

Human Adenylate Cyclase 3 (ADCY3) Interaktionspartner

  1. In peripheral organs, AC3 is present mainly in primary cilia in cells of the mesenchymal lineage. In epithelia, the apical cilium of renal and pancreatic tubules and of ductal plate in liver is AC3-negative whereas the cilium of basal cells of stratified epithelia is AC3-positive. Using fibroblasts cell culture, we show that AC3 appears at the plasma membrane of the primary cilium as soon as this organelle develops.

  2. The association signal of height-adjusted BMI at ADCY3 appeared to be driven by a missense variant and it was strongly correlated with expression of this gene.

  3. Data demonstrate that the expression of ADCY3 is regulated through an epigenetic mechanism.

  4. endoplasmic reticulum calcium store operated cAMP production occurred preferentially via the adenylate cyclase 3

  5. Genetically mutated serine(1076) of adenylyl cyclase III (ACIII) affects neither the cilial localization nor expression level of ACIII in olfactory sensory neurons.

  6. This study suggested that the adenylate cyclase 3 (ADCY3, 2p23.3) related to major depressive disorder.

  7. Data show that AC3 genetic polymorphisms are associated with decreased risk of obesity among adults but not in children in a Chinese Han population.

  8. expression of nodular ADCY6 (zeige ADCY6 Proteine), but not ADCY3, was lower than the expression of both in perinodular tissue, which may be part of the mechanisms occurring in the hyperfunctioning nodules

  9. Establishment of the mature glomerular array in transgenic mice requires adenylyl cyclase 3, a key component of the odorant receptor-mediated cyclic AMP-dependent signaling cascade.

  10. Fully differentiated human airway epithelial cells in culture are shown to express calcium-stimulated transmembrane adenylyl cyclase (tmAC) isoforms (types 1, 3, and 8) by reverse transcription polymerase chain reaction.

Mouse (Murine) Adenylate Cyclase 3 (ADCY3) Interaktionspartner

  1. Cell apoptosis in the testicular tissues of AC3(-/-) mice increased significantly compared with that in wild-type (AC3(+/+)) mice. The expression of 693 genes was altered in the testicular tissues of AC3(-/-) mice, including 330 up-regulated and 363 down-regulated gene expression, helping to elucidate the mechanisms underlying the sterility in AC3(-/-) male mice.

  2. AC3 may play a role in proximal olfactory signaling and play a role in the regulation of differentially expressed genes in mouse MOE.

  3. Data showed the presence mRNA of obligated downstream components of olfactory receptor signaling adenylyl cyclase 3 and olfactory G protein in the cerebral cortex of the mouse.

  4. increased Adcy3 activity robustly protect animals from diet-induced metabolic derangements

  5. Study identifies the transient expression of histone demethylase (zeige MBD2 Proteine) LSD1 (zeige KDM1A Proteine) and the OR-dependent expression of adenylyl cyclase 3 as requirements for initiation and stabilization of OR expression.

  6. Coexpression of serotonin receptor (zeige HTR1B Proteine) 5HT6 (zeige HTR6 Proteine) with adenylyl cyclase type III normalizes cilia structure and restores dendrite outgrowth.

  7. Data suggest that while ADCY3 is responsible for a share of the cAMP in osteoclasts, the reduction of cAMP levels in the absence of this gene is insufficient to augment differentiation or effect changes in bone mass in vivo.

  8. We conclude that AC3 in the main olfactory epithelium is required for detecting the mechanical force of airflow, which in turn may regulate odorant perception during sniffing.

  9. In primary culture and in situ in G93A SOD1 (zeige SOD1 Proteine) mice there is a large reduction in the proportion of motor neurons bearing a primary cilium.

  10. Maternal behavior was impaired in female mice deficient in adenylyl cyclase 3.

Cow (Bovine) Adenylate Cyclase 3 (ADCY3) Interaktionspartner

  1. Distinct mechanisms of regulation by Ca2 (zeige CA2 Proteine)+/calmodulin (zeige KRIT1 Proteine) of type 1 and 8 adenylyl cyclases support their different physiological roles.

ADCY3 Protein Überblick

Protein Überblick

This gene encodes adenylyl cyclase 3 which is a membrane-associated enzyme and catalyzes the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). This protein appears to be widely expressed in various human tissues and may be involved in a number of physiological and pathophysiological metabolic processes.

Alternative names and synonyms associated with ADCY3

  • adenylate cyclase 3 (ADCY3)
  • adenylate cyclase 3b (adcy3b)
  • DnaJ (Hsp40) homolog, subfamily C, member 27 (dnajc27)
  • adenylate cyclase 8 (brain) (ADCY8)
  • adenylate cyclase 3 (Ac3)
  • adenylate cyclase 3 (Adcy3)
  • adenylate cyclase 3 (LOC100343958)
  • AC3 Protein
  • ADCY3 Protein
  • ADCY8 Protein
  • Amac3 Protein
  • GB11637 Protein
  • mKIAA0511 Protein
  • si:ch211-153j24.5 Protein

Bezeichner auf Proteinebene für Adenylate Cyclase 3 Proteine (ADCY3)

adenylate cyclase 8 (brain) , adenylate cyclase type 3 , adenylate cyclase 3-like , adenylate cyclase 3 , AC-III , ATP pyrophosphate-lyase 3 , adenylate cyclase type III , adenylate cyclase, olfactive type , adenylyl cyclase 3 , adenylyl cyclase, type III , AC3 , type III adenylyl cyclase

GENE ID SPEZIES
459070 Pan troglodytes
564719 Danio rerio
693523 Macaca mulatta
100038110 Xenopus (Silurana) tropicalis
100372163 Saccoglossus kowalevskii
100471164 Ailuropoda melanoleuca
408363 Apis mellifera
482994 Canis lupus familiaris
109 Homo sapiens
104111 Mus musculus
64508 Rattus norvegicus
535603 Bos taurus
100343958 Oryctolagus cuniculus
100725667 Cavia porcellus
422013 Gallus gallus
101108203 Ovis aries
100514402 Sus scrofa
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