SOX2 (SOX2) ELISA Kits

Bezeichnung:
SRY (Sex Determining Region Y)-Box 2 ELISA Kits (SOX2)
Auf www.antikoerper-online.de finden Sie aktuell 35 SRY (Sex Determining Region Y)-Box 2 (SOX2) ELISA Kits von 12 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen SOX2 Antikörper (473) und SOX2 Proteine (32) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 555 SOX2 Produkte verfügbar.
Synonyme:
anop3, cb236, lcc, mcops3, Qscn6, Qsox, RGD1565646, rSOx, sox-2, SRY-box2, wu:fb83g04, wu:fc14d07, Xsox-2, ysb, zgc:65860, zgc:77389

Weitere ELISA Kits für SOX2 Interaktionspartner

Human SRY (Sex Determining Region Y)-Box 2 (SOX2) Interaktionspartner

  1. Sox2 plays an essential role in melanocyte transformation and melanoma growth.

  2. The lack of a tumorigenic role of Sox2 in melanoma might reflect a distinct stem cell program active in neural crest stem cells and during melanoma formation.

  3. Results suggest that the simultaneous evaluation of SRY (sex determining region Y)-box 2 protein (SOX2) and cyclin dependent kinase inhibitor 1A (p21 (zeige CDKN1A ELISA Kits)) in advanced endometrial cancer patients provides more accurate information for patient prognosis than either alone.

  4. Results suggest that targeting SRY (sex determining region Y)-box 2 protein (SOX2) in ovarian cancer may be therapeutically beneficial.

  5. Endogenous Plastic Somatic (ePS) cells in a latent state, i.e. lacking SOX2, OCT3/4 (zeige POU5F1 ELISA Kits) and NANOG (zeige NANOG ELISA Kits) (SON) expression, in non-diseased breast specimens through immunohistochemical analysis of previously identified ePS-specific biomarkers (CD73(+), EpCAM (zeige EPCAM ELISA Kits)(+) and CD90 (zeige THY1 ELISA Kits)(-)).

  6. Our results not only revealed the genetic plasticity contributing to drug resistance and stemness but also demonstrated the dominant role of SOX2 in maintenance of glioblastoma cancer stem cells.

  7. We show that the chromatin remodeling protein HMGA1 (zeige HMGA1 ELISA Kits) functions as a downstream effector of these biological responses to miR (zeige MLXIP ELISA Kits)-296-5p and regulates Sox2 expression, a master driver of cell stemness, by modifying chromatin architecture at the Sox2 promoter

  8. PARP-1 (zeige PARP1 ELISA Kits) stabilizes Sox2 binding to nucleosomes at suboptimal sites through cooperative interactions on DNA to regulate Sox2 pioneer activity at intractable genomic loci.

  9. Sox2 has a role in location and progression of gastric cancer

  10. Model highlights the essential role of SOX2 in commanding the squamous cell fate from different cells of origin and represents an invaluable tool for developing better intervention strategies.

Xenopus laevis SRY (Sex Determining Region Y)-Box 2 (SOX2) Interaktionspartner

  1. Sox2 is necessary for spinal cord regeneration and suggest a model whereby spinal cord injury activates proliferation of Sox2/3 expressing cells and their differentiation into neurons, a mechanism that is lost in non-regenerative froglets.

  2. Tail amputation results in a global increase of Sox2 levels and proliferation of Sox2-positive cells after spinal cord injury.

  3. Data indicate that pluripotency genes sox2, p63 and oct60 are upregulated early during the process of lens regeneration.

  4. Suggest that SOX2 directly upregulates FGF8 (zeige FGF8 ELISA Kits) gene expression in the early embryonic development of Xenopus.

  5. Continuous expression of Sox1 (zeige SOX1 ELISA Kits) and Sox2 in transgenic embryos represses neuron differentiation and inhibits anterior development while increasing cell proliferation.

  6. direct interaction and interdependence between the Otx2 (zeige OTX2 ELISA Kits) and Sox2 proteins coordinate Rax (zeige RAX ELISA Kits) expression in eye development, providing molecular linkages among the genes responsible for ocular malformation.

  7. Sox3 functions as an activator to induce expression of the early neural genes, sox2 and geminin in the absence of protein synthesis and to indirectly inhibit the Bmp target Xvent2

  8. A directional Wnt (zeige WNT2 ELISA Kits)/beta-catenin (zeige CTNNB1 ELISA Kits)-Sox2-proneural pathway regulates the transition from proliferation to differentiation in the retina.

Pig (Porcine) SRY (Sex Determining Region Y)-Box 2 (SOX2) Interaktionspartner

  1. Sox2 has a role in pluripotency in pig embryos

  2. Overexpression of Sox2 or Oct4 (zeige POU5F1 ELISA Kits) in bone mesenchymal stem cells in culture media containing a basic fibroblast growth factor (zeige FGF2 ELISA Kits) results in higher proliferation and differentiation compared to controls.

  3. cells isolated from umbilical cord express three transcription factors,Oct-4, Sox-2 & Nanog, found in pluripotent stem cell markers both at the mRNA and protein level

Cow (Bovine) SRY (Sex Determining Region Y)-Box 2 (SOX2) Interaktionspartner

  1. SOX2 localizes exclusively in the inner cell mass of bovine blastocysts, and its downregulation negatively impacts preimplantation development (zeige MTA2 ELISA Kits).

  2. analysis of pluripotency gene expression of OCT4, SOX2 and NANOG and mRNA levels of some of their downstream targets in bovine oocytes and early embryos

  3. Sox2 displayed relatively the same methylation levels between sperm and oocytes

Mouse (Murine) SRY (Sex Determining Region Y)-Box 2 (SOX2) Interaktionspartner

  1. Sox2 plays an essential role in melanocyte transformation and melanoma growth.

  2. The lack of a tumorigenic role of Sox2 in melanoma might reflect a distinct stem cell program active in neural crest stem cells and during melanoma formation.

  3. T, cooperatively with WNT (zeige WNT2 ELISA Kits) signaling, controls the progenitor state and the switch toward the mesodermal fate. Sox2 acts antagonistically and promotes neural development.

  4. Of the 28 proteins, only arginine methyltransferase 7 (PRMT7 (zeige PRMT7 ELISA Kits)) changed substantially during mouse embryogenesis and promoted the conversion of mouse fibroblasts into iPSCs. Specifically, PRMT7 (zeige PRMT7 ELISA Kits) replaced SOX2 in a factor-substitution assay, yielding iPSCs

  5. this study shows that Sox2 is expressed in activated B cells, but almost exclusively in those that have undergone IgH class switch recombination, enforced expression of Sox2 in splenic B cells severely inhibits AID expression and IgH class switch recombination, and that deletion of Sox2 increases the frequency of IgH:c-Myc (zeige MYC ELISA Kits) translocations

  6. Uncovering a Pitx2 (zeige PITX2 ELISA Kits)-Sox2-Lef-1 (zeige LEF1 ELISA Kits) transcriptional mechanism that regulates dental epithelial stem cells homeostasis and dental development.

  7. SOX2 has two independent roles during pituitary morphogenesis.

  8. PARP-1 (zeige PARP1 ELISA Kits) stabilizes Sox2 binding to nucleosomes at suboptimal sites through cooperative interactions on DNA to regulate Sox2 pioneer activity at intractable genomic loci.

  9. Maintenance of pluripotency is regulated by a network of transcription factors coordinated by Oct4 (zeige POU5F1 ELISA Kits), Sox2, and Nanog (zeige NANOG ELISA Kits); Trim24 (zeige TRIM24 ELISA Kits) significantly improved efficiency of cellular reprogramming, demonstrating its direct functionality in establishing pluripotency.

  10. the level of Cdk (zeige CDK4 ELISA Kits) kinase activity directly regulates Sox2 to tip the balance between self-renewal and differentiation in neural stem cells.

Zebrafish SRY (Sex Determining Region Y)-Box 2 (SOX2) Interaktionspartner

  1. Both sox2 and p27kip are regulated by the retinoic acid signal pathway and are essential for hair cell regeneration.

  2. a role of Sox2 as one of the proliferation initiators in ependymal cells after spinal cord injury

  3. Sox2 is identified as the unknown factor responsible for pineal photoreceptor prepatterning and performs this function independently of the BMP signaling.

  4. significant decreases in sox2 (up to 4-fold) expression following chilling and increase of sox2 (up to 3-fold) during warming of chilled embryos.

  5. Knockdown of the four B1 sox (zeige PIPOX ELISA Kits) genes sox2/3/19a/19b resulted in severe developmental abnormalities.

  6. sox2 is required for hair cell survival, as well as for transdifferentiation of support cells into hair cells during regeneration

  7. shows the occurrence and cell localization of the Sox-2 in chemosensory and mechanosensory organs of zebrafish during the embryonic stage to adult, suggest an involvement of Sox-2 in cell renewal of zebrafish sensory organs

  8. zebrafish sox2 gene is strongly expressed in neuromast progenitor cells, including those of the migrating lateral line

  9. Sox2 overlapping transcript has multiple transcription start sites associated with genomic features that indicate regulated expression, including highly conserved elements and chromatin marks characteristic of gene promoters.

SOX2 Antigen-Profil

Beschreibung des Gens

This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT).

Alternative names and synonyms associated with SOX2

  • SRY (sex determining region Y)-box 2 (LOC100231711) Elisa Kit
  • quiescin Q6 sulfhydryl oxidase 1 (Qsox1) Elisa Kit
  • SRY (sex determining region Y)-box 2 (SOX2) Elisa Kit
  • SRY (sex determining region Y)-box 2 (Sox2) Elisa Kit
  • SRY (sex determining region Y)-box 2 (sox2) Elisa Kit
  • SRY-box containing gene 2 (Sox2) Elisa Kit
  • SRY-box containing gene 2 (sox2) Elisa Kit
  • anop3 Elisa Kit
  • cb236 Elisa Kit
  • lcc Elisa Kit
  • mcops3 Elisa Kit
  • Qscn6 Elisa Kit
  • Qsox Elisa Kit
  • RGD1565646 Elisa Kit
  • rSOx Elisa Kit
  • sox-2 Elisa Kit
  • SRY-box2 Elisa Kit
  • wu:fb83g04 Elisa Kit
  • wu:fc14d07 Elisa Kit
  • Xsox-2 Elisa Kit
  • ysb Elisa Kit
  • zgc:65860 Elisa Kit
  • zgc:77389 Elisa Kit

Bezeichner auf Proteinebene für SOX2

SRY (sex determining region Y)-box 2 , FAD-dependent sulfhydryl oxidase-2 , rQSOX , sulfhydryl oxidase 1 , SRY-related HMG-box gene 2 , transcription factor SOX-2 , transcription factor SOX2 , SRY-box containing gene 2 , Sox2 transcription factor , cSox2 , delta EF2a , XSox2 , XlSOX-2 , sex-determining region Y-box 2 , transcription factor Sox-2 , SRY-box 2 , SRY-related HMG-box 2 , sex determining region Y-box 2 , soxp

GENE ID SPEZIES
100231711 Taeniopygia guttata
84491 Rattus norvegicus
6657 Homo sapiens
499593 Rattus norvegicus
396105 Gallus gallus
488092 Canis lupus familiaris
398000 Xenopus laevis
407739 Sus scrofa
784383 Bos taurus
101110563 Ovis aries
707039 Macaca mulatta
460869 Pan troglodytes
100379629 Felis catus
100714747 Cavia porcellus
20674 Mus musculus
378723 Danio rerio
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