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anti-Human DDC Antikörper:
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Human Polyclonal DDC Primary Antibody für IHC, IHC (p) - ABIN4305895
Koblinger, Füzesi, Ejdrygiewicz, Krajacic, Bains, Whelan: Characterization of A11 neurons projecting to the spinal cord of mice. in PLoS ONE 2014
Cow (Bovine) Polyclonal DDC Primary Antibody für IHC, IHC (p) - ABIN152519
Blechingberg, Holm, Johansen, Børglum, Nielsen: Aromatic l-amino acid decarboxylase expression profiling and isoform detection in the developing porcine brain. in Brain research 2009
Cow (Bovine) Polyclonal DDC Primary Antibody für IHC, WB - ABIN2776802
Ma, Beuten, Payne, Dupont, Elston, Li: Haplotype analysis indicates an association between the DOPA decarboxylase (DDC) gene and nicotine dependence. in Human molecular genetics 2005
Show all 2 Pubmed References
Human Polyclonal DDC Primary Antibody für IF (p), IHC (p) - ABIN725945
Hiramoto, Yamate, Kawanishi: Detection of Dopa-positive cells in mouse ovaries in response to ocular exposure to ultraviolet B rays. in Photodermatology, photoimmunology & photomedicine 2014
Human Polyclonal DDC Primary Antibody für ELISA, WB - ABIN250492
Voeller: Attention-deficit hyperactivity disorder (ADHD). in Journal of child neurology 2004
SNP rs10499695 located intronically in the gene DDC, (DOPA decarboxylase) is significantly associated with cognitive performance in diabetes 2.
Molecular characteristic and physiological role of DOPA-decarboxylase is reviewed.
We found that only the modified U1 snRNA (IVS-AAA (zeige APP Antikörper)) that completely matched both the intronic and exonic U1 binding sequences of the mutated DDC gene could correct splicing errors of either the mutated human DDC minigene or the mouse artificial splicing construct in vitro
The results of this study showed that Lack of Association Between Polymorphisms in Dopa decarboxylase Genes With Childhood
The data showed that L-DOPA decarboxylase constitutes a highly promising molecular marker for renal cell carcinoma (zeige MOK Antikörper).
gene study of 987 BPD (zeige MOD(MDG4) Antikörper) cases and 1110 healthy controls found an association between BPD (zeige MOD(MDG4) Antikörper) [ borderline personality disorder ]and single nucleotide polymorphism rs12718541 in the dopa decarboxylase gene
Results revealed the general picture of structural and/or functional effects of each DDC mutation linked to AADC deficiency mutations and help to guide therapeutic decision and prevent inappropriate use of treatment regiments.
A novel homozygous DDC variant in syndromic intellectual disability patients, c.1123C>T, resulting in p.Arg375Cys missense substitution.
Results indicate that miR (zeige MLXIP Antikörper)-145 has the ability to regulate DDC mRNA expression and potentially this occurs by recognizing its mRNA as a target.
Our results suggest that DDC may be a genetic modifier of the l-dopa response in Parkinson's disease
The unusual oxygen-consuming oxidative deamination reaction catalyzed by the pyridoxal 5'-phosphate (PLP (zeige PLP1 Antikörper)) enzyme DOPA decarboxylase (DDC) was here investigated.
Loss of Ddc appears to result in similar phenotypes as that of ADCC deficiency, thus zebrafish could be a good model for investigating pathogenetic mechanisms of AADC deficiency in children.
We found that only the modified U1 snRNA (IVS-AAA (zeige AAAS Antikörper)) that completely matched both the intronic and exonic U1 binding sequences of the mutated DDC gene could correct splicing errors of either the mutated human DDC minigene or the mouse artificial splicing construct in vitro
The data show that endothelial AADC plays an important role in cardiac synthesis of 5-HT and possibly in 5-HT-dependent regulation of nitric oxide generation.
Mash1 (zeige ASCL1 Antikörper) plays an important role in regulating the expression of AADC in type III cells in taste buds.
evidence for PKGIalpha-dependent phosphorylation and activation of neuronal AAAD (zeige AADAC Antikörper) in vitro, and introduce AAAD (zeige AADAC Antikörper) as a putative PKGIalpha substrate.
Data suggest a possible participation of aromatic L-amino acid decarboxylase (AADC) in the regulation of catecholamine biosynthesis in stellate ganglia of repeatedly stressed mice.
Results suggest that AADC expression begins at early stages of taste bud cell differentiation, and biogenic amines may act on taste bud differentiation of tongue epithelial cells, and further may regulate innervation of taste bud progenitor cells.
analysis of Ddc redefines the imprinted Grb10 (zeige GRB10 Antikörper) domain on mouse proximal chromosome 11 and identifies Ddc_exon1a as the first example of a heart-specific imprinted gene
the fact that renal DDC inversely correlated with renal sodium reabsorption suggest that renal and intestinal gender dimorphism in DDC could be related to sex-related differences in sodium balance observed between males and females
lowered expression of Atg6 (zeige BECN1 Antikörper) or Pi3K59F in Ddc-Gal4 (zeige LGALS4 Antikörper)-expressing neurons results in decreased longevity and associated age-dependent loss of locomotor ability. Inhibition of Atg6 (zeige BECN1 Antikörper) or Pi3K59F together with overexpression of the sole pro-survival Bcl-2 (zeige BCL2 Antikörper) Drosophila homolog Buffy in Ddc-Gal4 (zeige LGALS4 Antikörper)-expressing neurons resulted in further decrease in the survival
epidermal Ddc induction at pupariation is under the control of an extended genomic region that contains both positive and negative regulatory elements
Broad-Complex protein is required for Ddc activation at eclosion in Drosophila
evidence for a wound response pathway that senses aseptic breaks in the barrier epidermis of Drosophila embryos; a minimal 472-bp Ddc wound response enhancer requires a Grh (zeige GNRH1 Antikörper) protein binding site and the function of the grh (zeige GNRH1 Antikörper) gene
The Ddc locus exhibits a complicated pattern of variation apparently due to several evolutionary forces.
The involvement of DDC in a new pathway involved in Drosophila immunity increases the levels of dopamine, which is metabolized to produce reactive quinones that exert an antimicrobial effect on invading bacteria.
Combinatorial expression of tyrosine hydroxylase (TH (zeige TH Antikörper)), aromatic acid acid decarboxylase (AADC), and the brain-specific (zeige CALY Antikörper) isoform of the vesicular monoamine transporter, VMAT2.
The encoded protein catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. Defects in this gene are the cause of aromatic L-amino-acid decarboxylase deficiency (AADCD). AADCD deficiency is an inborn error in neurotransmitter metabolism that leads to combined serotonin and catecholamine deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
, L-aromatic dopa decarboxylase
, aromatic-L-amino acid decarboxylase
, aromatic amino acid decarboxylase
, L-Dopa decarboxylase
, aromatic L-amino acid decarboxylase
, DHPAA synthase
, alpha methyl dopa
, alpha-methotrexate deficient
, alpha-methyl dopa resistant
, dopa decarboxylase
, transcription unit No. 1
, 3,4-Dihydroxyphenylalanine decarboxylase
, dopamine decarboxylase
, transcription unit No. 3
, dopa decarboxylase (aromatic L-amino acid decarboxylase)
, Aromatic-L-amino-acid decarboxylase
, aromatic-L-amino-acid decarboxylase-like
, DOPA decarboxylase