anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6) Antikörper

Bezeichnung:
anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 Antikörper (XRCC6)
Auf www.antikoerper-online.de finden Sie aktuell 337 X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6) Antikörper von 28 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 Kits (16) und X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 Proteine (10) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 384 X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 Produkte verfügbar.
Synonyme:
70kDa, CTC75, CTCBF, G22p1, Ku70, Kup70, ML8, TLAA
Alle Antikörper anzeigen Gen GeneID UniProt
XRCC6 2547 P12956
XRCC6 14375 P23475
XRCC6 25019  

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Am meisten referenzierte anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 Antikörper

  1. Human Monoclonal XRCC6 Primary Antibody für IF, WB - ABIN396279 : Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. in Diabetes Care 2010 (PubMed)
    Zeige alle 5 Referenzen für 396279

  2. Human Monoclonal XRCC6 Primary Antibody für WB - ABIN395937 : Liu, Shete, Wang, El-Zein, Etzel, Liang, Armstrong, Tsavachidis, Gilbert, Aldape, Xing, Wu, Wei, Bondy: Gamma-radiation sensitivity and polymorphisms in RAD51L1 modulate glioma risk. in Carcinogenesis 2010 (PubMed)
    Zeige alle 5 Referenzen für 395937

  3. Human Polyclonal XRCC6 Primary Antibody für FACS, IF - ABIN651280 : Vishnudas, Miller: Ku70 regulates Bax-mediated pathogenesis in laminin-alpha2-deficient human muscle cells and mouse models of congenital muscular dystrophy. in Human molecular genetics 2009 (PubMed)
    Zeige alle 3 Referenzen für 651280

  4. Hamster Monoclonal XRCC6 Primary Antibody für ICC, FACS - ABIN151413 : Doster, Ziegler, Foermer, Rieker, Heeg, Bekeredjian-Ding: Phosphorothioate-modified CpG oligodeoxynucleotides mimic autoantigens and reveal a potential role for Toll-like receptor 9 in receptor revision. in Immunology 2013 (PubMed)
    Zeige alle 2 Referenzen für 151413

  5. Dog (Canine) Polyclonal XRCC6 Primary Antibody für IHC, WB - ABIN2778270 : Sawchuk, Mansilla-Soto, Alarcon, Singha, Langen, Bianchi, Lees-Miller, Nussenzweig, Cortes: Ku70/Ku80 and DNA-dependent protein kinase catalytic subunit modulate RAG-mediated cleavage: implications for the enforcement of the 12/23 rule. in The Journal of biological chemistry 2004 (PubMed)

  6. Human Polyclonal XRCC6 Primary Antibody für FACS, IF - ABIN651281 : Sobczuk, Smolarz, Romanowicz, Zadrozny, Baszczyński, Westfal, Pertyński: Analysis of the polymorphisms in non-homologous DNA end joining (NHEJ) gene Ku70 and Ligase IV in sporadic breast cancer in women. in Polish journal of pathology : official journal of the Polish Society of Pathologists 2010 (PubMed)

  7. Human Polyclonal XRCC6 Primary Antibody für ELISA, WB - ABIN190763 : Ribes-Zamora, Mihalek, Lichtarge, Bertuch: Distinct faces of the Ku heterodimer mediate DNA repair and telomeric functions. in Nature structural & molecular biology 2007 (PubMed)

Weitere Antikörper gegen X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 Interaktionspartner

Human X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6) Interaktionspartner

  1. found that the rs228593, rs2267437 and rs1805388 functional polymorphisms probably alter the level of expression of the ATM (zeige ATM Antikörper), XRCC6 and LIG4 (zeige LIG4 Antikörper) genes, respectively, being important in the maintenance of genomic instability in MDS (zeige PAFAH1B1 Antikörper)

  2. Data show that the increased acetylation of Ku autoantigen 70kDa (Ku70) in sirtuin 6 (zeige SIRT6 Antikörper) protein (SIRT6 (zeige SIRT6 Antikörper))-depleted cells disrupt its interaction with Bax (zeige BAX Antikörper) apoptosis regulator protein (Bax (zeige BAX Antikörper)), which finally resulted in Bax (zeige BAX Antikörper) mitochondrial translocalization.

  3. Ku70 (XRCC6) was found to bind directly within the CR4 of E1A (zeige BCKDHA Antikörper) from human adenovirus type 5.

  4. periodic phosphorylation of Ku70 by cyclin-cyclin (zeige PCNA Antikörper) dependent kinases prevents the interaction of Ku with replication origin after initiation events in S-phase.

  5. The results of this preclinical study imply that Ku70 might be a primary resistance factor of gemcitabine, and Ku70 silence could significantly chemo-sensitize gemcitabine in pancreatic cancer cells.

  6. results reveal that Src (zeige SRC Antikörper) plays a protective role against hyperactive apoptotic cell death by reducing apoptotic susceptibility through phosphorylation of Ku70 at Tyr (zeige TYR Antikörper)-530.

  7. High Expression of XRCC6 Promotes Human Osteosarcoma Cell Proliferation through the beta-Catenin (zeige CTNNB1 Antikörper)/Wnt (zeige WNT2 Antikörper) Signaling Pathway.

  8. Data show that X-ray repair cross-complementing protein 6 ( Ku70) is found to interact with closed circular DNA.

  9. The rs2267437 in XRCC6 was associated with increased initial DSB damage.

  10. Ku70 expression may play an important role in hepatocellular carcinoma development

Mouse (Murine) X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6) Interaktionspartner

  1. Study found that emphysema occurred in ku70(-/-) mice at the age of three-months old, and that Bax deficiency was able to suppress it. These results suggest that Bax-mediated apoptosis induces emphysema in ku70(-/-) mice.

  2. Bax deficiency appeared to delay the development of emphysema. This study suggests that enhanced Bax activity exacerbates the negative impact of Ku70 deletion

  3. Ku (ku70/ku80 (zeige XRCC5 Antikörper) heterodimer)roles in nonhomologous end joining and base excision repair pathways of DNA repair are overviewed.

  4. A novel role for free Ku70 and free Ku80 (zeige XRCC5 Antikörper) in altering base excision repair.

  5. A novel function of Ku70 essential for colon homeostasis.

  6. Overexpression of Bcl2 rescues the hematopoietic stem cell defect in Ku70-deficient mice by restoration of quiescence.

  7. This study highlights Ku70 as an important player not only in maintaining genomic stability through NHEJ-dependent functions, but also in regulating pancreatic beta-cell proliferation, a novel NHEJ-independent function.

  8. Ku70/80 binds to DNA double strand breaks (DSB) in all cell cycle stages and is likely actively displaced from DSB ends to free the DNA ends for DNA end resection and thus homologous recombination to occur.

  9. The findings suggest that Artemis (zeige DCLRE1C Antikörper) can work in not only the Ku-dependent repair process, but also the Ku-independent process at DNA double-strand break in living epithelial cells.

  10. These findings clearly indicate that Ku70 plays a key role in regulation of the Ku80 (zeige XRCC5 Antikörper) expression level in and the radioresistance of lung epithelial cells.

X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6) Antigen-Profil

Beschreibung des Gens

The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.

Alternative names and synonyms associated with X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6)

  • X-ray repair complementing defective repair in Chinese hamster cells 6 (XRCC6) Antikörper
  • ATP-dependent DNA helicase II, 70 kDa subunit (Bm1_41430) Antikörper
  • ATP-dependent DNA helicase II, 70 kDa subunit (LOC100351956) Antikörper
  • X-ray repair complementing defective repair in Chinese hamster cells 6 (xrcc6) Antikörper
  • X-ray repair complementing defective repair in Chinese hamster cells 6 (Xrcc6) Antikörper
  • 70kDa Antikörper
  • CTC75 Antikörper
  • CTCBF Antikörper
  • G22p1 Antikörper
  • Ku70 Antikörper
  • Kup70 Antikörper
  • ML8 Antikörper
  • TLAA Antikörper

Bezeichner auf Proteinebene für XRCC6

ATP-dependent DNA helicase 2 subunit 1 , ATP-dependent DNA helicase II, 70 kDa subunit , X-ray repair complementing defective repair in Chinese hamster cells 6 (Ku autoantigen, 70kDa) , X-ray repair cross-complementing protein 6 , 5'-dRP lyase Ku70 , 5'-deoxyribose-5-phosphate lyase Ku70 , 70 kDa subunit of Ku antigen , ATP-dependent DNA helicase II 70 kDa subunit , CTC box binding factor 75 kDa subunit , CTC box-binding factor 75 kDa subunit , DNA repair protein XRCC6 , Ku autoantigen p70 subunit , Ku autoantigen, 70kDa , lupus Ku autoantigen protein p70 , thyroid autoantigen 70kD (Ku antigen) , thyroid autoantigen 70kDa (Ku antigen) , thyroid-lupus autoantigen p70 , 5'-dRP/AP lyase Ku70 , CTC75 , CTCBF , Ku p70 , ku autoantigen protein p70 homolog , thyroid autoantigen 70 kDa , Ku70 DNA-binding component of DNA-dependent proteinkinase complex (thyroid autoantigen 70 kDa) , thyroid autoantigen , X-ray repair cross-complementing protein 5

GENE ID SPEZIES
465902 Pan troglodytes
6103167 Brugia malayi
100351956 Oryctolagus cuniculus
398357 Xenopus laevis
474485 Canis lupus familiaris
510132 Bos taurus
707975 Macaca mulatta
100173902 Pongo abelii
2547 Homo sapiens
14375 Mus musculus
25019 Rattus norvegicus
395767 Gallus gallus
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