POLD4 Proteine (POLD4)

Bezeichnung:
Polymerase (DNA-Directed), delta 4, Accessory Subunit Proteine (POLD4)
Auf www.antikoerper-online.de finden Sie aktuell 6 Polymerase (DNA-Directed), delta 4, Accessory Subunit (POLD4) Proteine von 4 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen POLD4 Antikörper (8) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 15 POLD4 Produkte verfügbar.
Synonyme:
2410012M21Rik, AI463381, AW060307, p12, POLDS
alle Proteine anzeigen Gen GeneID UniProt
POLD4 69745 Q9CWP8
POLD4 57804 Q9HCU8
POLD4 617899 Q3T0X9

Weitere Synonyme anzeigen

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Weitere Proteine zu POLD4 Interaktionspartnern

Mouse (Murine) Polymerase (DNA-Directed), delta 4, Accessory Subunit (POLD4) Interaktionspartner

  1. The identification of RNF8 (zeige RNF8 Proteine) allows new insights into the integration of the control of p12 (zeige CDK2AP1 Proteine) degradation by different DNA damage signaling pathways.

Human Polymerase (DNA-Directed), delta 4, Accessory Subunit (POLD4) Interaktionspartner

  1. the p12 (zeige POLE4 Proteine)/Pol delta (zeige POLD1 Proteine) is a target as a nuclear substrate of mu-calpain (zeige CAPNL1 Proteine) in a calcium-triggered apoptosis and appears to be a potential marker in the study of the chemotherapy of cancer therapies.

  2. A parallel study of Pol delta4 and Pol delta3 in Okazaki fragment processing provides evidence for a role of Pol delta3 in DNA replication

  3. Findings provide evidence for the novel concept that Pol delta3 has a role in lagging strand synthesis, and that both forms of Pol delta3 and 4 may participate in DNA replication in higher eukaryotic cells.

  4. ubiquitination of p12 through CRL4(Cdt2) and subsequent degradation form one mechanism by which a cell responds to DNA damage to inhibit fork progression.

  5. Data indicate that CRL4(Cdt2) regulates the degradation of the p12 subunit of Pol delta4.

  6. The identification of RNF8 (zeige RNF8 Proteine) allows new insights into the integration of the control of p12 (zeige POLE4 Proteine) degradation by different DNA damage signaling pathways.

  7. Low POLD4 (zeige POLDIP2 Proteine) is associated with lung cancer.

  8. these results indicate that POLD4 (zeige POLDIP2 Proteine) is required for the in vitro pol delta (zeige POLD1 Proteine) activity, and that it functions in cell proliferation and maintenance of genomic stability of human cells.

  9. pol delta (zeige POLD1 Proteine) interacts with PCNA (zeige PCNA Proteine) via at least two of its subunits, and p12 (zeige POLE4 Proteine) could play a role in stabilizing the overall pol delta (zeige POLD1 Proteine)-PCNA (zeige PCNA Proteine) complex as well as pol delta (zeige POLD1 Proteine) itself

  10. The DNA polymerase delta enzyme, as well as the isolated p12 subunit, stimulates the DNA helicase activity of Bloom's syndrome helicase.

POLD4 Protein Überblick

Protein Überblick

This gene encodes the smallest subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. The encoded protein enhances the activity of DNA polymerase delta and plays a role in fork repair and stabilization through interactions with the DNA helicase Bloom syndrome protein. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Alternative names and synonyms associated with POLD4

  • polymerase (DNA-directed), delta 4 (POLD4)
  • polymerase (DNA-directed), delta 4 (Pold4)
  • polymerase (DNA-directed), delta 4, accessory subunit (POLD4)
  • 2410012M21Rik Protein
  • AI463381 Protein
  • AW060307 Protein
  • p12 Protein
  • POLDS Protein

Bezeichner auf Proteinebene für POLD4

DNA polymerase delta subunit 4 , DNA polymerase delta subunit p12 , DNA-directed DNA polymerase delta 4 , DNA polymerase delta smallest subunit p12

GENE ID SPEZIES
617899 Bos taurus
69745 Mus musculus
57804 Homo sapiens
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