anti-MUS81 (MUS81) Antikörper

Bezeichnung:
anti-MUS81 Endonuclease Homolog (S. Cerevisiae) Antikörper (MUS81)
Auf www.antikoerper-online.de finden Sie aktuell 41 MUS81 Endonuclease Homolog (S. Cerevisiae) (MUS81) Antikörper von 11 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen MUS81 Proteine (6) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 51 MUS81 Produkte verfügbar.
Synonyme:
1200008A18Rik, AI182501, ARABIDOPSIS THALIANA MMS AND UV SENSITIVE 81, ATMUS81, AW045863, CG3026, Dmel\\CG3026, EG:BACR7A4.16, F6I18.220, F6I18_220, GB15332, MMS AND UV SENSITIVE 81, MUS81, slx3, wu:fc26g01, zgc:66489, zgc:91801

Meistgesuchte Reaktivitäten zu anti-MUS81 (MUS81) Antikörper

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anti-Mouse (Murine) MUS81 Antikörper:

anti-Human MUS81 Antikörper:

anti-Rat (Rattus) MUS81 Antikörper:

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Am meisten referenzierte anti-MUS81 Antikörper

  1. Human Monoclonal MUS81 Primary Antibody für FACS, ICC - ABIN108570 : Nomura, Adachi, Koyama: Human Mus81 and FANCB independently contribute to repair of DNA damage during replication. in Genes to cells : devoted to molecular & cellular mechanisms 2007 (PubMed)
    Zeige alle 11 Referenzen für 108570

  2. Human Monoclonal MUS81 Primary Antibody für CyTOF, FACS - ABIN151532 : Rodrigue, Coulombe, Jacquet, Gagné, Roques, Gobeil, Poirier, Masson: The RAD51 paralogs ensure cellular protection against mitotic defects and aneuploidy. in Journal of cell science 2013 (PubMed)
    Zeige alle 2 Referenzen für 151532

  3. Human Polyclonal MUS81 Primary Antibody für ICC, IF - ABIN442031 : Sun, Brieño-Enríquez, Cornelius, Modzelewski, Maley, Campbell-Peterson, Holloway, Cohen: FancJ (Brip1) loss-of-function allele results in spermatogonial cell depletion during embryogenesis and altered processing of crossover sites during meiotic prophase I in mice. in Chromosoma 2016 (PubMed)

Weitere Antikörper gegen MUS81 Interaktionspartner

Fruit Fly (Drosophila melanogaster) MUS81 Endonuclease Homolog (S. Cerevisiae) (MUS81) Interaktionspartner

  1. spontaneous mitotic crossovers that occur when FANCM is missing are dependent on MUS312 and either MUS81 or SLX1.

  2. did not find any role for MUS81-MMS4 in meiotic crossing over

Arabidopsis thaliana MUS81 Endonuclease Homolog (S. Cerevisiae) (MUS81) Interaktionspartner

  1. SEND1 has at most a minor role in resolution of the Holliday junction but acts as an essential backup to MUS81 for resolution of toxic replication structures to ensure genome stability and to maintain telomere integrity.

  2. Data show that DNA polymerase zeta catalytic subunit REV3 (zeige REV3L Antikörper) cooperates with ATP-dependent DNA helicase RECQ4A and e ndonuclease MUS81 to repair DNA interstrand cross links.

  3. RECQ4A and MUS81 define RAD5A-independent pathways of DNA repair. RECQ4A and MUS81 act in parallel pathways presumably to resolve replication-associated DNA intermediates.

  4. The role of AtMUS81 in meiotic and mitotic recombination.

  5. AtMUS81 is involved in a secondary subset of meiotic crossovers that are interference insensitive.

  6. The role of MUS81 in the reproduction and growth of A. thaliana, via its expression and metabolism during meiosis, is reported.

  7. Both MUS81-EME1 (zeige EME1 Antikörper) endonuclease complexes are involved in DNA recombination and repair processes in Arabidopsis.

Mouse (Murine) MUS81 Endonuclease Homolog (S. Cerevisiae) (MUS81) Interaktionspartner

  1. this study shows that immune rejection of prostate cancer cells relies on Mus81 and STING

  2. Our study highlights the importance of the cooperation between Rad54 (zeige RAD54L Antikörper) and Mus81 for mediating DNA DSB repair and restraining chromosome missegregation.

  3. Mus81 knockdown improves the chemosensitivity of HCC (zeige FAM126A Antikörper) cells by inducing S-phase arrest and promoting apoptosis through CHK1 (zeige CHEK1 Antikörper) pathway, suggesting Mus81 as a novel therapeutic target for HCC (zeige FAM126A Antikörper).

  4. Using mice deficient in both Mus81 and the FA pathway protein FancC (zeige FANCC Antikörper), we show both proteins cooperate in parallel pathways, as concomitant loss of FancC (zeige FANCC Antikörper) and Mus81 triggered cell-type-specific proliferation arrest, apoptosis and DNA damage accumulation in utero.

  5. Data indicate that SLX1 and MUS81-EME1 (zeige EME1 Antikörper) nucleases act together to resolve Holliday junctions (HJs) in a manner that requires tethering to SLX4 (zeige BTBD12 Antikörper).

  6. FBH1 (zeige FBXO18 Antikörper) helicase (zeige DNA2 Antikörper) activity is required to eliminate cells with excessive replication stress through the generation of MUS81-induced DNA double-strand breaks.

  7. data indicate that an important role for Chk2 (zeige CHEK2 Antikörper) is maintaining lymphocyte development and that dual inactivation of Chk2 (zeige CHEK2 Antikörper) and Mus81 remarkably inhibits cancer

  8. studies demonstrate a critical role for the proper biallelic expression of the mammalian Mus81 in the maintenance of genomic integrity and tumor suppression

  9. Mus81 acts at a late step in the repair of cross-link-induced lesions

  10. Mus81-Eme1 (zeige EME1 Antikörper)- and Rad54 (zeige RAD54L Antikörper)-mediated homologous recombination are involved in the same DNA replication-dependent interstrand crosslinks repair pathway

Human MUS81 Endonuclease Homolog (S. Cerevisiae) (MUS81) Interaktionspartner

  1. RECQ5 (zeige RECQL5 Antikörper) removes RAD51 (zeige RAD51 Antikörper) filaments stabilizing stalled replication forks at common fragile sites and hence facilitates CFS cleavage by MUS81-EME1 (zeige EME1 Antikörper).

  2. The mitotic DNA synthesis is RAD52 (zeige RAD52 Antikörper) dependent, and RAD52 (zeige RAD52 Antikörper) is required for the timely recruitment of MUS81 and POLD3 (zeige POLD3 Antikörper) to common fragile sites in early mitosis.

  3. Data suggest that dimeric GEN1 (zeige GEN1 Antikörper) binds with high affinity/selectivity to Holliday junctions, introducing two symmetrical hydrolytic cleavages of phosphodiester backbone; at present, less is known about SLX1-SLX4 (zeige BTBD12 Antikörper)-MUS81-EME1 (zeige EME1 Antikörper) resolving enzyme complex. (GEN1 (zeige GEN1 Antikörper) = Holliday junction 5' flap (zeige ALOX5AP Antikörper) endonuclease; SLX = structure-specific endonuclease subunit; MUS81 = MUS81 endonuclease; EME1 (zeige EME1 Antikörper) = essential meiotic endonuclease 1) [REVIEW]

  4. down-regulation of MUS81 expression in ovarian cancer cells inhibited cell proliferation and colony formation ability, and influenced cell cycle progression

  5. SLX4 (zeige BTBD12 Antikörper)-SLX1 Protein-independent Down-regulation of MUS81-EME1 (zeige EME1 Antikörper) Protein by HIV-1 Viral Protein R (Vpr).

  6. Mus81 sumoylation is important for normal mitotic chromosome congression.

  7. Data suggest that the ATM (zeige ATM Antikörper)/Chk2 (zeige CHEK2 Antikörper) may promote the repair of DNA damage caused by cisplatin by sustaining methyl methanesulfonate and ultraviolet-sensitive gene clone 81, and the double-strand breaks generated by methyl methanesulfonate and ultraviolet-sensitive gene clone 81 may activate the ATM (zeige ATM Antikörper)/Chk2 (zeige CHEK2 Antikörper) pathway.

  8. Avoiding damage formation through invalidation of Mus81-Eme2 (zeige EME2 Antikörper) and Mre11 (zeige MRE11A Antikörper), or preventing damage signaling by turning off the ATM (zeige ATM Antikörper) pathway, suppresses the replication phenotypes of Chk1 (zeige CHEK1 Antikörper)-deficient cells.

  9. Mus81 knockdown improves the chemosensitivity of HCC (zeige FAM126A Antikörper) cells by inducing S-phase arrest and promoting apoptosis through CHK1 (zeige CHEK1 Antikörper) pathway, suggesting Mus81 as a novel therapeutic target for HCC (zeige FAM126A Antikörper).

  10. Mus81 regulates the rate of DNA replication during normal growth by promoting replication fork progression while reducing the frequency of replication initiation events.

MUS81 Antigen-Profil

Beschreibung des Gens

Interacts with EME1 and EME2 to form a DNA structure- specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication forks.

Alternative names and synonyms associated with MUS81

  • CG3026 gene product from transcript CG3026-RA (mus81) Antikörper
  • MUS81 endonuclease homolog (S. cerevisiae) (MUS81) Antikörper
  • MUS81 structure-specific endonuclease subunit (mus81) Antikörper
  • mus81 protein (mus81) Antikörper
  • crossover junction endonuclease MUS81 (MUS81) Antikörper
  • Mus81p (MUS81) Antikörper
  • Holliday junction resolvase subunit Mus81 (mus81) Antikörper
  • MUS81 protein (mus81) Antikörper
  • MUS81 endonuclease homolog (yeast) (Mus81) Antikörper
  • MUS81 endonuclease homolog (yeast) (mus81) Antikörper
  • MUS81 structure-specific endonuclease subunit (MUS81) Antikörper
  • MUS81 structure-specific endonuclease subunit (Mus81) Antikörper
  • similar to S. cerevisiae MUS81p (YDR386W) which is part of an endonuclease involved in repair of damaged DNA replication forks (MUS81) Antikörper
  • 1200008A18Rik Antikörper
  • AI182501 Antikörper
  • ARABIDOPSIS THALIANA MMS AND UV SENSITIVE 81 Antikörper
  • ATMUS81 Antikörper
  • AW045863 Antikörper
  • CG3026 Antikörper
  • Dmel\\CG3026 Antikörper
  • EG:BACR7A4.16 Antikörper
  • F6I18.220 Antikörper
  • F6I18_220 Antikörper
  • GB15332 Antikörper
  • MMS AND UV SENSITIVE 81 Antikörper
  • MUS81 Antikörper
  • slx3 Antikörper
  • wu:fc26g01 Antikörper
  • zgc:66489 Antikörper
  • zgc:91801 Antikörper

Bezeichner auf Proteinebene für MUS81

CG3026-PA , mus81-PA , crossover junction endonuclease MUS81 , MUS81 endonuclease homolog (S. cerevisiae) , MUS81 endonuclease homolog , MUS81 protein , crossover junction endonuclease MUS81-like , SLX3 structure-specific endonuclease subunit homolog , hypothetical protein

GENE ID SPEZIES
31044 Drosophila melanogaster
466667 Pan troglodytes
476021 Canis lupus familiaris
496413 Xenopus (Silurana) tropicalis
725951 Apis mellifera
829211 Arabidopsis thaliana
851994 Saccharomyces cerevisiae S288c
2539004 Schizosaccharomyces pombe 972h-
10804405 Sordaria macrospora k-hell
100029893 Monodelphis domestica
100051745 Equus caballus
100459560 Pongo abelii
100464481 Ailuropoda melanoleuca
100511000 Sus scrofa
100590455 Nomascus leucogenys
71711 Mus musculus
406839 Danio rerio
80198 Homo sapiens
293678 Rattus norvegicus
3647146 Candida albicans SC5314
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