MGMT (MGMT) ELISA Kits

Bezeichnung:
O6-Methylguanine-DNA-Methyltransferase ELISA Kits (MGMT)
Auf www.antikoerper-online.de finden Sie aktuell 30 O6-Methylguanine-DNA-Methyltransferase (MGMT) ELISA Kits von 10 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen MGMT Antikörper (214) und MGMT Proteine (25) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 281 MGMT Produkte verfügbar.
Synonyme:
Agat, AGT, AI267024

Am meisten referenzierte MGMT ELISA Kits

  1. Human MGMT ELISA Kit für Sandwich ELISA - ABIN416869 : Safdar, Payne, Tu, Taite: Targeted nitric oxide delivery preferentially induces glioma cell chemosensitivity via altered p53 and O(6) -methylguanine-DNA methyltransferase activity. in Biotechnology and bioengineering 2013 (PubMed)

Weitere ELISA Kits für MGMT Interaktionspartner

Human O6-Methylguanine-DNA-Methyltransferase (MGMT) Interaktionspartner

  1. MGMT protein expression assessed by immunohistochemistry did not play an important role as a predictive marker for alkylating agents.

  2. Glioblastoma patients with high IFIT1 (zeige IFIT1 ELISA Kits) and low MGMT expression have an improved prognosis.

  3. Glioblastoma patients with high expression of hepatocyte growth factor (zeige HGF ELISA Kits) or unmethylated O(6)-methylguanine-DNA methyltransferase may benefit from onartuzumab plus bevacizumab chemotherapy.

  4. results demonstrate MGMT methylation is a reliable and independent prognostic factor in DAs (zeige ube3a ELISA Kits). Methylation of MGMT is associated with poor prognosis in patients with stage III DAs (zeige ube3a ELISA Kits)

  5. investigation of MGMT promoter methylation and in particular BRAF (zeige BRAF ELISA Kits) V600E mutations represent reliable additional tools to sustain differentiation of Giant Cell Glioblastoma (gcGBM) from Pleomorphic Xanthoastrocytoma (PXA) on a molecular basis. Based on these data specific BRAF (zeige BRAF ELISA Kits) kinase inhibitors could represent a promising agent in the therapy of PXA and their use should be emphasized.

  6. Efficacy of TMZ in adrenocortical carcinoma cells does not seem to be limited by low methylation of MGMT.

  7. MGMT is involved in gastric carcinogenesis via downregulation of MMP2 (zeige MMP2 ELISA Kits).

  8. Study suggests that treatment effects of upfront radiotherapy plus concomitant and maintenance temozolomide might offset some of the beneficial effects of cytoreductive surgery in case of a methylated MGMT promoter whereas this unfortunately seems not be true for unmethylated tumors

  9. our results suggest that an aberrant messenger RNA expression may be the outcome of CpG, CHG, and CHH methylation in O(6)-methylguanine-DNA methyltransferase, whereas outcome of CHG and CHH methylation in runt-related transcription factor 3 promoters along with risk factors such as consumption of tobacco, betel nut, and smoking habits in esophageal cancer from Northeast India

  10. Loss of O-6-methylguanine-DNA methyltransferase protein was very frequent in the incidence of esophageal cancer from North Indian patients, and methylation of the promoter region of O-6-methylguanine-DNA methyltransferase was significantly associated in its downregulation

Mouse (Murine) O6-Methylguanine-DNA-Methyltransferase (MGMT) Interaktionspartner

  1. Snell, GHKRO, and PAPPA (zeige PAPPA ELISA Kits)-KO mice express high levels of two proteins involved in DNA repair, O-6-methylguanine-DNA methyltransferase (MGMT) and N-myc downstream-regulated gene 1 (NDRG1 (zeige NDRG1 ELISA Kits)).

  2. This study demonstrates for the first time a non-linear dose-response for alkylation-induced colorectal carcinogenesis and reveals DNA repair by MGMT, but not AAG, as a key node in determining a carcinogenic threshold.

  3. Findings suggest that O6-methylguanine-DNA methyltransferase (MGMT)-mediated temozolomide resistance is associated with increased histone acetylation.

  4. Loss of MGMT expression and high Ezrin (zeige EZR ELISA Kits) protein expression leads to esophageal cancer.

  5. Both base excision repair and O6-methylguanine-DNA methyltransferase protect against methylation-induced colon carcinogenesis.

  6. ta indicate that Zik1 and Gja9 demonstrated cancer-specific aberrant DNA methylation, whereas, Cdkn2a/p16, Igfbp3, Mgmt, Id4, and Cxcr4 were methylated in both the AOM tumors and normal colon mucosa.

  7. Roles of MGMT and MLH1 (zeige MLH1 ELISA Kits) proteins in alkylation-induced apoptosis and mutagenesis.

  8. Repression of MGMT is associated with precancerous conditions in hyperplastic mucosa adjacent to colon cancer

  9. GAMT (zeige GAMT ELISA Kits) and AGAT (zeige GATM ELISA Kits) mRNA are up-regulated 5.4- and 1.9-fold respectively in adult mdx (zeige DMD ELISA Kits) muscle compared to C57

  10. MGMT-deficient cells would likely exhibit an increased mutational burden, but only following exposures to specific environmental mutagens such as the tobacco carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK).

MGMT Antigen-Profil

Beschreibung des Gens

Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a

Alternative names and synonyms associated with MGMT

  • O-6-methylguanine-DNA methyltransferase (MGMT) Elisa Kit
  • O-6-methylguanine-DNA methyltransferase (Mgmt) Elisa Kit
  • Agat Elisa Kit
  • AGT Elisa Kit
  • AI267024 Elisa Kit

Bezeichner auf Proteinebene für MGMT

6-O-methylguanine-DNA methyltransferase , O-6-methylguanine-DNA-alkyltransferase , O6-methylguanine-DNA methyltransferase , methylated-DNA--protein-cysteine methyltransferase , methylguanine-DNA methyltransferase , O-6-alkylguanine-DNA alkyltransferase , 0-6-methylguanine-DNA methyltransferase , O(6)-alkylguanine-DNA alkyltransferase , O6-alkylguanine-DNA alkyltransferase , O6-methylguanine-DNA methyltranferase , O6-alkylguanine-DNA-alkyltransferase , O6-methylguanine-DNA-methyltransferase

GENE ID SPEZIES
4255 Homo sapiens
17314 Mus musculus
25332 Rattus norvegicus
100733185 Cavia porcellus
100155050 Sus scrofa
616091 Bos taurus
442978 Canis lupus familiaris
423965 Gallus gallus
101106897 Ovis aries
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