anti-LIG3 (LIG3) Antikörper

Bezeichnung:
anti-Ligase III, DNA, ATP-Dependent Antikörper (LIG3)
Auf www.antikoerper-online.de finden Sie aktuell 68 Ligase III, DNA, ATP-Dependent (LIG3) Antikörper von 17 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen LIG3 Kits (6) und LIG3 Proteine (5) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 83 LIG3 Produkte verfügbar.
Synonyme:
An02g06890, AO090003000668, D11Wsu78e, DDBDRAFT_0218523, DDBDRAFT_0232266, DDB_0218523, DDB_0232266, LIG2, LIG3, orf36, wu:fb12c02, wu:fd10b03, wu:fm79b09
Alle Antikörper anzeigen Gen GeneID UniProt
LIG3 3980 P49916
LIG3 303369  
LIG3 16882  

Alle Spezies anzeigen

Weitere Synonyme anzeigen

Meistgesuchte Reaktivitäten zu anti-LIG3 (LIG3) Antikörper

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anti-Human LIG3 Antikörper:

anti-Rat (Rattus) LIG3 Antikörper:

anti-Mouse (Murine) LIG3 Antikörper:

Alle verfügbaren anti-LIG3 Antikörper

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Am meisten referenzierte anti-LIG3 Antikörper

  1. Chicken Monoclonal LIG3 Primary Antibody für BP, ICC - ABIN445494 : Leppard, Dong, Mackey, Tomkinson: Physical and functional interaction between DNA ligase IIIalpha and poly(ADP-Ribose) polymerase 1 in DNA single-strand break repair. in Molecular and cellular biology 2003 (PubMed)
    Zeige alle 10 Referenzen für 445494

  2. Human Monoclonal LIG3 Primary Antibody für ICC, IF - ABIN151084 : Klungland, Hoess, Gunz, Constantinou, Clarkson, Doetsch, Bolton, Wood, Lindahl: Base excision repair of oxidative DNA damage activated by XPG protein. in Molecular cell 1999 (PubMed)
    Zeige alle 8 Referenzen für 151084

  3. Dog (Canine) Monoclonal LIG3 Primary Antibody für IF, WB - ABIN968692 : Chen, Tomkinson, Ramos, Mackey, Danehower, Walter, Schultz, Besterman, Husain: Mammalian DNA ligase III: molecular cloning, chromosomal localization, and expression in spermatocytes undergoing meiotic recombination. in Molecular and cellular biology 1995 (PubMed)
    Zeige alle 4 Referenzen für 968692

  4. Human Polyclonal LIG3 Primary Antibody für ICC, IF - ABIN4305495 : Fan, Li, Small, Rassool: Cells expressing FLT3/ITD mutations exhibit elevated repair errors generated through alternative NHEJ pathways: implications for genomic instability and therapy. in Blood 2010 (PubMed)
    Zeige alle 2 Referenzen für 4305495

  5. Mouse (Murine) Polyclonal LIG3 Primary Antibody für IHC, WB - ABIN3022649 : Xu, Zhang, Zhang, Meng, Zhang, Jiang, Xu, Van Meter, Seluanov, Gorbunova, Mao: SIRT6 rescues the age related decline in base excision repair in a PARP1-dependent manner. in Cell cycle (Georgetown, Tex.) 2015 (PubMed)

  6. Human Polyclonal LIG3 Primary Antibody für EIA, WB - ABIN951931 : Cotner-Gohara, Kim, Hammel, Tainer, Tomkinson, Ellenberger: Human DNA ligase III recognizes DNA ends by dynamic switching between two DNA-bound states. in Biochemistry 2010 (PubMed)

Weitere Antikörper gegen LIG3 Interaktionspartner

Human Ligase III, DNA, ATP-Dependent (LIG3) Interaktionspartner

  1. The g.29661G>A and g.29059C>T polymorphisms of LIG3 may play a role in the keratoconus and Fuchs endothelial corneal dystrophy pathogenesis and can be considered as markers in these diseases.

  2. A computational approach to determine susceptibility to cancer by evaluating the deleterious effect of nsSNP in XRCC1 (zeige XRCC1 Antikörper) gene on binding interaction of XRCC1 (zeige XRCC1 Antikörper) protein with ligase III.

  3. In the context of tyrosine kinase (zeige TXK Antikörper)-activated leukemias, c-MYC (zeige MYC Antikörper) contributes to aberrant DNA repair through downstream targets LIG3 and PARP1 (zeige PARP1 Antikörper) up-regulation.

  4. there is an absolute requirement for fully functional DNA ligase III (LIG3), but not ligase IV (LIG4 (zeige LIG4 Antikörper)), to facilitate the escape from a telomere-driven crisis.

  5. Results show that overexpression of DNA ligase III in mitochondria improves mitochondrial base excision repair and enhances cell survival after oxidative stress.

  6. data confirm previous work showing that Lig3 is required to maintain mtDNA integrity and function, and highlight a new function of ATM (zeige ATM Antikörper) in regulating DNA Lig3 stability and consequently mtDNA repair

  7. Human Mre11 (zeige MRE11A Antikörper)/human Rad50 (zeige RAD50 Antikörper)/Nbs1 (zeige NBN Antikörper) and DNA ligase IIIalpha/XRCC1 (zeige XRCC1 Antikörper) protein complexes act together in an alternative nonhomologous end joining pathway.

  8. Using our cohort of 480 breast cancer patients, we provide replicated evidence that a polymorphism near the LIG3 gene is associated with acute skin toxicity following radiotherapy.

  9. results establish a role for Lig3 in mitochondria, but distinguish it from its interacting protein Xrcc1 (zeige XRCC1 Antikörper)

  10. The collective results support a "jackknife model" in which the ZnF (zeige ZNF629 Antikörper) loads ligase III onto nicked DNA and conformational changes deliver DNA into the active site.

Mouse (Murine) Ligase III, DNA, ATP-Dependent (LIG3) Interaktionspartner

  1. Results show that overexpression of DNA ligase III in mitochondria improves mitochondrial base excision repair and enhances cell survival after oxidative stress.

  2. data confirm previous work showing that Lig3 is required to maintain mtDNA integrity and function, and highlight a new function of ATM (zeige ATM Antikörper) in regulating DNA Lig3 stability and consequently mtDNA repair

  3. Lig3 has an essential role in mtDNA maintenance but is dispensable for the viability of cultured cells

  4. data reveal that the critical biological role of Lig3 is to maintain mtDNA integrity and not Xrcc1 (zeige XRCC1 Antikörper)-dependent DNA repair

  5. results establish a role for Lig3 in mitochondria, but distinguish it from its interacting protein Xrcc1 (zeige XRCC1 Antikörper)

  6. Early embryonic lethality is due to targeted inactivation of DNA ligase III.

LIG3 Antigen-Profil

Beschreibung des Gens

This gene is a member of the DNA ligase family. Each member of this family encodes a protein that catalyzes the joining of DNA ends but they each have a distinct role in DNA metabolism. The protein encoded by this gene is involved in excision repair and is located in both the mitochondria and nucleus, with translation initiation from the upstream start codon allowing for transport to the mitochondria and translation initiation from a downstream start codon allowing for transport to the nucleus. Additionally, alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Alternative names and synonyms associated with LIG3

  • ligase III, DNA, ATP-dependent (lig3) Antikörper
  • ligase III, DNA, ATP-dependent (LIG3) Antikörper
  • DNA ligase III (orf36) Antikörper
  • DNA ligase 3 (ANI_1_2644024) Antikörper
  • DNA ligase 3 (AOR_1_1174154) Antikörper
  • DNA ligase III (Bm1_22840) Antikörper
  • BRCT domain-containing protein (lig3) Antikörper
  • ligase III, DNA, ATP-dependent (Lig3) Antikörper
  • An02g06890 Antikörper
  • AO090003000668 Antikörper
  • D11Wsu78e Antikörper
  • DDBDRAFT_0218523 Antikörper
  • DDBDRAFT_0232266 Antikörper
  • DDB_0218523 Antikörper
  • DDB_0232266 Antikörper
  • LIG2 Antikörper
  • LIG3 Antikörper
  • orf36 Antikörper
  • wu:fb12c02 Antikörper
  • wu:fd10b03 Antikörper
  • wu:fm79b09 Antikörper

Bezeichner auf Proteinebene für LIG3

ligase III, DNA, ATP-dependent , DNA ligase 3 , DNA ligase (ATP) 3 , DNA ligase 3 isoform alpha , DNA ligase III , DNA ligase 3-like , ligase II, DNA, ATP-dependent , polydeoxyribonucleotide synthase [ATP] 3

GENE ID SPEZIES
336509 Danio rerio
417530 Gallus gallus
454581 Pan troglodytes
491145 Canis lupus familiaris
514719 Bos taurus
549105 Xenopus (Silurana) tropicalis
715181 Macaca mulatta
955080 Heliothis zea virus 1
4979178 Aspergillus niger CBS 513.88
5991803 Aspergillus oryzae RIB40
6099475 Brugia malayi
8624245 Dictyostelium discoideum AX4
100071671 Equus caballus
100344941 Oryctolagus cuniculus
100405358 Callithrix jacchus
100455958 Pongo abelii
100464510 Ailuropoda melanoleuca
100634887 Amphimedon queenslandica
3980 Homo sapiens
303369 Rattus norvegicus
16882 Mus musculus
Ausgewählte Anbieter für anti-LIG3 (LIG3) Antikörper
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