anti-General Transcription Factor IIH, Polypeptide 5 (GTF2H5) Antikörper

Bezeichnung:
anti-General Transcription Factor IIH, Polypeptide 5 Antikörper (GTF2H5)
Auf www.antikoerper-online.de finden Sie aktuell 26 General Transcription Factor IIH, Polypeptide 5 (GTF2H5) Antikörper von 10 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen General Transcription Factor IIH, Polypeptide 5 Proteine (7) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 35 General Transcription Factor IIH, Polypeptide 5 Produkte verfügbar.
Synonyme:
34kDa, 2700017P07Rik, 2810432H05Rik, 5033417D07Rik, bA120J8.2, BTF2, BTF2 p34, C6orf175, C730029A10, CG8019, D5Ertd679e, D17Wsu155e, DhR25, DhXPB, Dmel\CG8019, DmXPB, ERCC3, Hay, hwr, i50, ms(3)nc2, nc2, RGD1560991, si:dkey-12h9.4, TFB5, TFIIH, TGF2H5, TTD, TTD-A, TTDA, XPB, Xpb/hay, zgc:153434
Alle Antikörper anzeigen Gen GeneID UniProt
GTF2H5 209357 Q8VD76
GTF2H5 404672 Q6ZYL4
GTF2H5 502227  

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Weitere Antikörper gegen General Transcription Factor IIH, Polypeptide 5 Interaktionspartner

Mouse (Murine) General Transcription Factor IIH, Polypeptide 5 (GTF2H5) Interaktionspartner

  1. extensive molecular analyses unveiled that wild-type TFIIH (zeige GTF2H4 Antikörper) cooperated in an ATP-dependent manner with PGC1-alpha (zeige PPARGC1A Antikörper) as well as with the deacetylase SIRT1 (zeige SIRT1 Antikörper), thereby contributing to the PGC1 (zeige PPARGC1A Antikörper)-a deacetylation by SIRT1 (zeige SIRT1 Antikörper)

  2. Mutations in TFIIH (zeige GTF2H4 Antikörper) causing trichothiodystrophy are responsible for defects in ribosomal RNA production and processing.

  3. Data show that that B2 RNA, when present with Pol II in promoter-bound complexes, specifically represses CTD phosphorylation by TFIIH (zeige GTF2H4 Antikörper).

  4. Molecular analyses performed on the mice brain tissue demonstrate that TFIIH (zeige GTF2H4 Antikörper) is required for the stabilization of thyroid hormone (zeige PTH Antikörper) receptors (TR) to their DNA-responsive elements.

Human General Transcription Factor IIH, Polypeptide 5 (GTF2H5) Interaktionspartner

  1. Low levels of GTF2H5 are associated with enhanced prognosis in high-grade serous ovarian cancer patients and may contribute to cisplatin sensitization.

  2. Transcriptional differences found between various TFIIH subunit (zeige GTF2H4 Antikörper) variants participate in the phenotypic variability observed among xeroderma pigmentosum, XP associated with Cockayne syndrome, and trichothiodystrophy individuals.

  3. Findings give new insights into the behavior of TTDA within the context of a living cell and thereby shed light on the complex phenotype of TTD-A patients.

  4. p8/TTD-A, the tenth subunit of TFIIH (zeige GTF2H1 Antikörper), has a critical role in DNA repair where it triggers DNA opening by stimulating XPB ATPase (zeige DNAH8 Antikörper) activity together with the damage recognition factor XPC (zeige XPC Antikörper)-hHR23B (zeige RAD23B Antikörper).

  5. TTDA is the first Transcription Factor IIH subunit with a primarily nucleotide excision repair-dedicated role in vivo.

  6. The solution structure of the p8/TTD-A protein, a small alpha/beta protein built around an antiparallel beta-sheet that forms a homodimer with an extended interface, is reported.

Fruit Fly (Drosophila melanogaster) General Transcription Factor IIH, Polypeptide 5 (GTF2H5) Interaktionspartner

  1. The data demonstrate that dMYC repression and dMYC-dependent overgrowth in the Hfp hypomorph is further impaired in the C-terminal Hay/XPB mutant background.

  2. analysis of physical and functional interactions between Drosophila homologue of Swc6/p18Hamlet (zeige ZNHIT1 Antikörper) subunit of the SWR1/SRCAP (zeige SRCAP Antikörper) chromatin-remodeling complex with the DNA repair/transcription factor TFIIH

  3. regulation of dmyc requires interaction between the transcriptional repressor Hfp and the DNA helicase subunit of TFIIH, Haywire (Hay)

  4. Drosophila TFIIH (hay) has roles in DNA repair and transcription

  5. TFIIH is a basal transcription factor, but mutations in the subunit encoded by hay have specific effects in the transcription of some genes.

  6. TFIIH core is initially located in the cytoplasm of syncytial blastoderm embryos, and that after mitotic division ten and until the cellular blastoderm stage, the core moves from the cytoplasm to the nucleus.

General Transcription Factor IIH, Polypeptide 5 (GTF2H5) Antigen-Profil

Beschreibung des Gens

This gene encodes a subunit of transcription/repair factor TFIIH, which functions in gene transcription and DNA repair. This protein stimulates ERCC3/XPB ATPase activity to trigger DNA opening during DNA repair, and is implicated in regulating cellular levels of TFIIH. Mutations in this gene result in trichothiodystrophy, complementation group A.

Alternative names and synonyms associated with General Transcription Factor IIH, Polypeptide 5 (GTF2H5)

  • general transcription factor IIH, polypeptide 5 (gtf2h5) Antikörper
  • general transcription factor IIH, polypeptide 5 (GTF2H5) Antikörper
  • general transcription factor IIH, polypeptide 3 (Gtf2h3) Antikörper
  • general transcription factor IIH, polypeptide 4, 52kDa (GTF2H4) Antikörper
  • general transcription factor IIH, polypeptide 5 (Gtf2h5) Antikörper
  • haywire (hay) Antikörper
  • 34kDa Antikörper
  • 2700017P07Rik Antikörper
  • 2810432H05Rik Antikörper
  • 5033417D07Rik Antikörper
  • bA120J8.2 Antikörper
  • BTF2 Antikörper
  • BTF2 p34 Antikörper
  • C6orf175 Antikörper
  • C730029A10 Antikörper
  • CG8019 Antikörper
  • D5Ertd679e Antikörper
  • D17Wsu155e Antikörper
  • DhR25 Antikörper
  • DhXPB Antikörper
  • Dmel\CG8019 Antikörper
  • DmXPB Antikörper
  • ERCC3 Antikörper
  • Hay Antikörper
  • hwr Antikörper
  • i50 Antikörper
  • ms(3)nc2 Antikörper
  • nc2 Antikörper
  • RGD1560991 Antikörper
  • si:dkey-12h9.4 Antikörper
  • TFB5 Antikörper
  • TFIIH Antikörper
  • TGF2H5 Antikörper
  • TTD Antikörper
  • TTD-A Antikörper
  • TTDA Antikörper
  • XPB Antikörper
  • Xpb/hay Antikörper
  • zgc:153434 Antikörper

Bezeichner auf Proteinebene für GTF2H5

general transcription factor IIH, polypeptide 5 , general transcription factor IIH subunit 5 , BTF2-p34 , TFIIH basal transcription factor complex p34 subunit , basic transcription factor 2 34 kDa subunit , general transcription factor IIH subunit 3 , general transcription factor IIH, polypeptide 3, 34kDa , general transcription factor IIH subunit 4 , TFB5 ortholog , TFIIH basal transcription factor complex TTD-A subunit , TFIIH basal transcription factor complex TTDA subunit , general transcription factor IIH polypeptide 5 , CG8019-PA , CG8019-PB , hay-PA , hay-PB

GENE ID SPEZIES
550052 Xenopus (Silurana) tropicalis
612182 Canis lupus familiaris
700107 Macaca mulatta
738799 Pan troglodytes
751713 Danio rerio
100222149 Taeniopygia guttata
209357 Mus musculus
100144458 Sus scrofa
404672 Homo sapiens
66467 Mus musculus
502227 Rattus norvegicus
518046 Bos taurus
769754 Gallus gallus
39202 Drosophila melanogaster
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