anti-ERCC6 (ERCC6) Antikörper

Bezeichnung:
anti-Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6 Antikörper (ERCC6)
Auf www.antikoerper-online.de finden Sie aktuell 98 Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6 (ERCC6) Antikörper von 20 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen ERCC6 Proteine (3) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 107 ERCC6 Produkte verfügbar.
Synonyme:
4732403I04, ARMD5, C130058G22Rik, CKN2, COFS, COFS1, CSB, ercc6, RAD26, UVSS1
Alle Antikörper anzeigen Gen GeneID UniProt
ERCC6 2074 Q03468
ERCC6 306274  
ERCC6 319955  

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Weitere Synonyme anzeigen

Meistgesuchte Reaktivitäten zu anti-ERCC6 (ERCC6) Antikörper

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anti-Human ERCC6 Antikörper:

anti-Rat (Rattus) ERCC6 Antikörper:

anti-Mouse (Murine) ERCC6 Antikörper:

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Am meisten referenzierte anti-ERCC6 Antikörper

  1. Human Polyclonal ERCC6 Primary Antibody für FACS, WB - ABIN654126 : Lamesch, Li, Milstein, Fan, Hao, Szabo, Hu, Venkatesan, Bethel, Martin, Rogers, Lawlor, McLaren, Dricot, Borick, Cusick, Vandenhaute, Dunham, Hill, Vidal: hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. in Genomics 2007 (PubMed)
    Zeige alle 2 Referenzen für 654126

  2. Human Polyclonal ERCC6 Primary Antibody für IHC, ELISA - ABIN1450836 : Troelstra, van Gool, de Wit, Vermeulen, Bootsma, Hoeijmakers: ERCC6, a member of a subfamily of putative helicases, is involved in Cockayne's syndrome and preferential repair of active genes. in Cell 1993 (PubMed)
    Zeige alle 2 Referenzen für 1450836

  3. Human Polyclonal ERCC6 Primary Antibody für WB - ABIN656032 : Venter, Adams, Myers, Li, Mural, Sutton, Smith, Yandell, Evans, Holt, Gocayne, Amanatides, Ballew, Huson, Wortman, Zhang, Kodira, Zheng, Chen, Skupski, Subramanian, Thomas, Zhang, Gabor Miklos et al.: The sequence of the human genome. ... in Science (New York, N.Y.) 2001 (PubMed)
    Zeige alle 2 Referenzen für 656032

Weitere Antikörper gegen ERCC6 Interaktionspartner

Human Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6 (ERCC6) Interaktionspartner

  1. pro-apoptotic effects observed after CSB ablation

  2. the Elongin A ubiquitin ligase and the CSB protein function together in a common pathway in response to Pol II stalling and DNA damage

  3. No significant association exists between ERCC6 polymorphisms and bladder cancer risk.

  4. CSB plays a role in the homeostasis and function of human neurons. CSB-deficient neural networks displayed altered electrophysiological activity, including decreased synchrony, and reduced synapse density.

  5. Study found that ERCC6 transcription may be epigenetically regulated in lens epithelial cells of age-related nuclear cataract leading to its repression.

  6. Mutation of Cockayne syndrome B (CSB) affects neuronal gene expression and differentiation, so we attempted to bypass its function by expressing downstream target genes.

  7. The frequency of the XPD (zeige ERCC2 Antikörper) 312Asn allele was significantly higher in T >/= 2 high grade than in T >/= 2 low grade tumors (p = 0.036); the ERCC6 1097Val/Val genotype was strongly associated with muscle-invasive tumors.

  8. new role of VCP/p97 (zeige vcp Antikörper) segregase in the timely processing of ubiquitinated CSB from damaged chromatin.

  9. CSB and CTCF (zeige CTCF Antikörper) can regulate each other's chromatin association, thereby modulating chromatin structure and coordinating gene expression in response to oxidative stress.

  10. Transcription inhibition reduced accumulation of CSB at sites of monoadducts and interstrand crosslinks, but it did not affect recruitment to (although slightly affected retention at) oxidative DNA damage.

Mouse (Murine) Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6 (ERCC6) Interaktionspartner

  1. Our data show that in addition to promoting repeat expansion, CSB does in fact protect the genome from germ line expansions in the FXD mouse model.

  2. loss of CSB affects tandem-repeat expansions in a gender and cell-type-specific manner

  3. CSB has been shown to regulate processes such as the transcriptional recovery after DNA damage, the p53 (zeige TP53 Antikörper) transcriptional response, the response to hypoxia, the response IGF-1 (zeige IGF1 Antikörper), transactivation of nuclear receptors, transcription of housekeeping genes

  4. CSB and PCAF (zeige KAT2B Antikörper) play cooperative roles to establish the active state of rRNA genes by histone acetylation

  5. Csb-/- neural precursors exhibited defective self-renewal in the neurosphere assay.

  6. Dysmyelination not demyelination causes neurological symptoms in preweaned mice in a cs-b xp-c murine model of Cockayne syndrome

  7. Testicular nuclear receptor 4 (TR4 (zeige NR2C2 Antikörper)) regulates UV light-induced responses via Cockayne syndrome B protein-mediated transcription-coupled DNA repair

  8. Data suggest that Cockayne syndrome B protein protects CAG repeats from expansion by either active reduction of the tract length during parent-child transmission, or by antagonizing the action of OGG1 (zeige OGG1 Antikörper), which tends to promote expansion in somatic cells.

  9. These results suggested that reduced repair of a DNA topoisomerase I-DNA covalent complex because of truncated CSB proteins is involved in the pathogenesis of CS-B.

  10. MtDNA mutations are highly increased in cells from subcutaneous fat of aged Csb(m/m) mice

ERCC6 Antigen-Profil

Beschreibung des Gens

This gene encodes a DNA-binding protein that is important in transcription-coupled excision repair. The encoded protein has ATP-stimulated ATPase activity, interacts with several transcription and excision repair proteins, and may promote complex formation at DNA repair sites. Mutations in this gene are associated with Cockayne syndrome type B and cerebrooculofacioskeletal syndrome 1. Naturally-occurring readthrough transcription occurs between this gene and the adjacent PGBD3 gene (GeneID:267004), and results in a fusion protein that shares sequence with the product of each individual gene. The readthrough locus is represented by GeneID:101243544.

Alternative names and synonyms associated with ERCC6

  • excision repair cross-complementing rodent repair deficiency, complementation group 6 (ERCC6) Antikörper
  • excision repair cross-complementing rodent repair deficiency, complementation group 6 (Ercc6) Antikörper
  • excision repair cross-complementing rodent repair deficiency, complementation group 6 (ercc6) Antikörper
  • 4732403I04 Antikörper
  • ARMD5 Antikörper
  • C130058G22Rik Antikörper
  • CKN2 Antikörper
  • COFS Antikörper
  • COFS1 Antikörper
  • CSB Antikörper
  • ercc6 Antikörper
  • RAD26 Antikörper
  • UVSS1 Antikörper

Bezeichner auf Proteinebene für ERCC6

ATP-dependent helicase ERCC6 , Cockayne syndrome group B protein , DNA excision repair protein ERCC-6 , cockayne syndrome protein CSB , CS group B correcting , excision repair cross-complementing rodent repair deficiency, complementation group 6

GENE ID SPEZIES
2074 Homo sapiens
306274 Rattus norvegicus
319955 Mus musculus
548810 Xenopus (Silurana) tropicalis
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