anti-APLF (APLF) Antikörper

Bezeichnung:
anti-Aprataxin and PNKP Like Factor Antikörper (APLF)
Auf www.antikoerper-online.de finden Sie aktuell 38 Aprataxin and PNKP Like Factor (APLF) Antikörper von 9 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen APLF Proteine (5) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 45 APLF Produkte verfügbar.
Synonyme:
2010301N04Rik, AI452191, APFL, APLF, C2orf13, DKFZp459J1223, PALF, RGD1565557, Xip1

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anti-Human APLF Antikörper:

anti-Mouse (Murine) APLF Antikörper:

anti-Rat (Rattus) APLF Antikörper:

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Weitere Antikörper gegen APLF Interaktionspartner

Human Aprataxin and PNKP Like Factor (APLF) Interaktionspartner

  1. These data suggest functional requirements for Ku and XRCC4 (zeige XRCC4 Antikörper) in APLF-dependent NHEJ and a unique role for Ku as a factor required to facilitate the nuclear retention of APLF.

  2. APLF promotes the assembly and activity of multi-protein Ku-DNA complexes containing all of the Non-homologous end joining (NHEJ) factors required for DNA ligation.

  3. Polynucleotide kinase and aprataxin-like (zeige APTX Antikörper) forkhead-associated protein (PALF) acts as both a single-stranded DNA endonuclease and a single-stranded DNA 3' exonuclease (zeige EXO1 Antikörper) and can participate in DNA end joining in a biochemical system.

  4. only a positive association (OR=1.58, 95% CI 1.05-2.46, P=0.027) was obtained for XRCC1 (zeige XRCC1 Antikörper) (Arg280His

  5. APLF has a role in chromosomal DNA double-strand break repair.

  6. The poly(ADP-ribose)-regulated protein APLF as a DNA-damage-specific histone chaperone.

  7. The authors present solution structures of the two poly(ADP-ribose)-binding zinc finger modules of aprataxin and PNK-like factor (APLF), revealing a novel type of zinc finger.

  8. These data identify APLF as a novel component of the cellular response to DNA strand breaks in human cells.

  9. PALF is novel human AP endonuclease with conserved zinc-finger-like motifs involved in DNA strand break responses.

  10. APLF is an ATM (zeige ATM Antikörper) target that is involved in nonhomologous end-joining and facilitates double-strand break repair, likely via interactions with Ku and XRCC4 (zeige XRCC4 Antikörper)-DNA ligase IV (zeige LIG4 Antikörper).

Mouse (Murine) Aprataxin and PNKP Like Factor (APLF) Interaktionspartner

  1. the downregulation of histone chaperone Aprataxin (zeige APTX Antikörper) PNK (zeige PNKP Antikörper)-like factor (APLF) promotes reprogramming by augmenting the expression of E-cadherin (zeige CDH1 Antikörper).

  2. APLF has a role in chromosomal DNA double-strand break repair.

APLF Antigen-Profil

Beschreibung des Gens

C2ORF13 is a component of the cellular response to chromosomal DNA single- and double-strand breaks (Iles et al., 2007

Alternative names and synonyms associated with APLF

  • aprataxin and PNKP like factor (APLF) Antikörper
  • aprataxin and PNKP like factor (aplf) Antikörper
  • aprataxin and PNKP like factor (LOC100342776) Antikörper
  • aprataxin and PNKP like factor (Aplf) Antikörper
  • 2010301N04Rik Antikörper
  • AI452191 Antikörper
  • APFL Antikörper
  • APLF Antikörper
  • C2orf13 Antikörper
  • DKFZp459J1223 Antikörper
  • PALF Antikörper
  • RGD1565557 Antikörper
  • Xip1 Antikörper

Bezeichner auf Proteinebene für APLF

aprataxin and PNKP like factor , aprataxin and PNK-like factor-like , PNK and APTX-like FHA domain-containing protein , PNK and APTX-like FHA protein , XRCC1-interacting protein 1 , aprataxin and PNK-like factor , aprataxin- and PNK-like factor , apurinic-apyrimidinic endonuclease APLF

GENE ID SPEZIES
481405 Canis lupus familiaris
705875 Macaca mulatta
100061683 Equus caballus
100127823 Xenopus (Silurana) tropicalis
100173335 Pongo abelii
100342776 Oryctolagus cuniculus
100389227 Callithrix jacchus
100595038 Nomascus leucogenys
200558 Homo sapiens
72103 Mus musculus
507989 Bos taurus
500247 Rattus norvegicus
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