anti-Glutaminase 2 (Liver, Mitochondrial) (GLS2) Antikörper

Bezeichnung:
anti-Glutaminase 2 (Liver, Mitochondrial) Antikörper (GLS2)
Auf www.antikoerper-online.de finden Sie aktuell 65 Glutaminase 2 (Liver, Mitochondrial) (GLS2) Antikörper von 14 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Glutaminase 2 (Liver, Mitochondrial) Kits (7) und Glutaminase 2 (Liver, Mitochondrial) Proteine (5) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 84 Glutaminase 2 (Liver, Mitochondrial) Produkte verfügbar.
Synonyme:
A330074B06Rik, AI195532, Ga, GLS, hLGA, Lga, si:ch211-216k22.10

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Am meisten referenzierte anti-Glutaminase 2 (Liver, Mitochondrial) Antikörper

  1. Cow (Bovine) Polyclonal GLS2 Primary Antibody für IHC, WB - ABIN2781319 : Toriumi, Mouri, Narusawa, Aoyama, Ikawa, Lu, Nagai, Mamiya, Kim, Nabeshima: Prenatal NMDA receptor antagonism impaired proliferation of neuronal progenitor, leading to fewer glutamatergic neurons in the prefrontal cortex. in Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2012 (PubMed)
    Zeige alle 2 Referenzen für 2781319

  2. Human Polyclonal GLS2 Primary Antibody für ELISA, ICC - ABIN4314469 : Gross, Demo, Dennison, Chen, Chernov-Rogan, Goyal, Janes, Laidig, Lewis, Li, Mackinnon, Parlati, Rodriguez, Shwonek, Sjogren, Stanton, Wang, Yang, Zhao, Bennett: Antitumor activity of the glutaminase inhibitor CB-839 in triple-negative breast cancer. in Molecular cancer therapeutics 2014 (PubMed)

  3. Human Polyclonal GLS2 Primary Antibody für IHC (p), WB - ABIN652216 : Shroff, Eberlin, Dang, Gouw, Gabay, Adam, Bellovin, Tran, Philbrick, Garcia-Ocana, Casey, Li, Dang, Zare, Felsher: MYC oncogene overexpression drives renal cell carcinoma in a mouse model through glutamine metabolism. in Proceedings of the National Academy of Sciences of the United States of America 2015 (PubMed)

Weitere Antikörper gegen Glutaminase 2 (Liver, Mitochondrial) Interaktionspartner

Human Glutaminase 2 (Liver, Mitochondrial) (GLS2) Interaktionspartner

  1. This study assessed the relation of GLS2 downregulation in glioblastoma cells to its methylation and TP53 (zeige TP53 Antikörper) status. Aberrant methylation of CpG islands, appear to contribute to silencing of GLS2 in glioblastoma cells by a mechanism bypassing TP53 (zeige TP53 Antikörper) mutations.

  2. Non-glutaminolysis function of GLS2 inhibits migration and invasion of hepatocellular carcinoma cells by repressing the epithelial-mesenchymal transition via the Dicer (zeige DICER1 Antikörper)-miR (zeige MLXIP Antikörper)-34a-Snail (zeige SNAI1 Antikörper) axis.

  3. observe that while miR (zeige MLXIP Antikörper)-23 is capable of down-regulating the shortened KGA (zeige GLS Antikörper) 3'UTR (zeige UTS2R Antikörper), it has only minor impact on the full-length KGA (zeige GLS Antikörper) 3'UTR (zeige UTS2R Antikörper), demonstrating that additional potent negative regulation of GLS (zeige GLS Antikörper) expression exists beyond this single microRNA targeting site

  4. the crystal structure of full-length KGA (zeige GLS Antikörper) and present a small-angle X-ray scattering model for full-length GLS2. These structures explain these proteins' compromised ability to assemble into catalytically active supra-tetrameric filaments, as previously shown for GAC (zeige GLS Antikörper).

  5. Cox (zeige COX8A Antikörper) multivariate regression analysis demonstrated that DUOX1 (zeige DUOX1 Antikörper), GLS2, FBP1 (zeige FBP1 Antikörper) and age were independent risk factors for the prognosis of HCC (zeige FAM126A Antikörper) patients after surgery

  6. As a p53 target, GLS2 mediates p53's function in metastasis suppression through inhibiting Rac1.

  7. IDO (zeige IDO1 Antikörper), through GCN2 (zeige EIF2AK4 Antikörper) kinase activation, downregulates the levels of TCRcomplex tchain and cMyc (zeige MYC Antikörper), resulting in the suppression of Tcell proliferation and a reduction in the levels of LDHA (zeige LDHA Antikörper) and GLS2

  8. GABAergic neurons and astrocytes express Gls (zeige GLS Antikörper) and Gls2 isoenzymes in nucleus and mitochondria, in addition to glutamatergic neurons

  9. Phosphate-activated glutaminase and GAD65 (zeige GAD2 Antikörper)/67 concentrations are compared in Alzheimer's disease cerebellum versus normal cerebellum controls

  10. GLS2 expression is significantly decreased in hepatocellular carcinoma.

Mouse (Murine) Glutaminase 2 (Liver, Mitochondrial) (GLS2) Interaktionspartner

  1. Gls2 expression is regulated by the dietary protein/carbohydrate ratio. This effect was not observed in Ppara (zeige PPARA Antikörper)-null mice.

  2. Study demonstrated expression of alternative transcripts of the mammalian Gls2 gene. Transcriptional mechanisms giving rise to GLS2 variants and isolation of novel GLS2 transcripts in human, rat and mouse are presented.

  3. Phosphate-activated glutaminase (GLS2) is a p53 (zeige TP53 Antikörper)-inducible regulator of glutamine (zeige GFPT1 Antikörper) metabolism and reactive oxygen species

Glutaminase 2 (Liver, Mitochondrial) (GLS2) Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene is a mitochondrial phosphate-activated glutaminase that catalyzes the hydrolysis of glutamine to stoichiometric amounts of glutamate and ammonia. This protein is functionally similar to the kidney glutaminase but is a little smaller in size. Originally thought to be liver-specific, this protein has been found in other tissues as well. At least one transcribed pseudogene has been found for this gene.

Alternative names and synonyms associated with Glutaminase 2 (Liver, Mitochondrial) (GLS2)

  • glutaminase 2 (glsA2) Antikörper
  • glutaminase 2 (LOAG_03311) Antikörper
  • glutaminase 2 (liver, mitochondrial) (gls2) Antikörper
  • glutaminase 2 (liver, mitochondrial) (GLS2) Antikörper
  • glutaminase 2 (liver, mitochondrial) (Gls2) Antikörper
  • A330074B06Rik Antikörper
  • AI195532 Antikörper
  • Ga Antikörper
  • GLS Antikörper
  • hLGA Antikörper
  • Lga Antikörper
  • si:ch211-216k22.10 Antikörper

Bezeichner auf Proteinebene für GLS2

glutaminase 2 , L-glutamine amidohydrolase , breast cell glutaminase , glutaminase I , glutaminase liver isoform, mitochondrial , phosphate-activated glutaminase , phosphate-dependent glutaminase , L-glutaminase , liver mitochondrial glutaminase , GLS

GENE ID SPEZIES
8710836 Citrobacter rodentium ICC168
9940699 Loa loa
100006303 Danio rerio
27165 Homo sapiens
100686499 Canis lupus familiaris
539561 Bos taurus
216456 Mus musculus
192268 Rattus norvegicus
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