anti-Lysyl Oxidase-Like 2 (LOXL2) Antikörper

Bezeichnung:
anti-Lysyl Oxidase-Like 2 Antikörper (LOXL2)
Auf www.antikoerper-online.de finden Sie aktuell 108 Lysyl Oxidase-Like 2 (LOXL2) Antikörper von 19 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Lysyl Oxidase-Like 2 Proteine (29) und Lysyl Oxidase-Like 2 Kits (27) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 173 Lysyl Oxidase-Like 2 Produkte verfügbar.
Synonyme:
1110004B06Rik, 4930526G11Rik, 9430067E15Rik, CG4402, Dmel\\CG4402, dmlox-2, Dmloxl-2, GB13360, LOR2, lox2-like, loxl-2, LOXL2, WS9-14

Meistgesuchte Reaktivitäten zu anti-Lysyl Oxidase-Like 2 (LOXL2) Antikörper

Wählen Sie die Spezies und Applikation aus

anti-Human Antikörper:

anti-Mouse (Murine) Antikörper:

anti-Rat (Rattus) Antikörper:

Alle verfügbaren anti-Lysyl Oxidase-Like 2 Antikörper

Sie gelangen zu unserer vorgefilterten Suche.

Am meisten referenzierte anti-Lysyl Oxidase-Like 2 Antikörper

  1. Human Monoclonal LOXL2 Primary Antibody für ELISA, WB - ABIN396576 : Rodriguez, Vaysberg, Mikels, McCauley, Velayo, Garcia, Smith: Modulation of lysyl oxidase-like 2 enzymatic activity by an allosteric antibody inhibitor. in The Journal of biological chemistry 2010 (PubMed)
    Zeige alle 5 Referenzen für 396576

  2. Human Polyclonal LOXL2 Primary Antibody für EIA, WB - ABIN953202 : Rückert, Joensson, Saeger, Grützmann, Pilarsky: Functional analysis of LOXL2 in pancreatic carcinoma. in International journal of colorectal disease 2010 (PubMed)
    Zeige alle 4 Referenzen für 953202

  3. Human Monoclonal LOXL2 Primary Antibody für ELISA, WB - ABIN561690 : Fujimoto, Tajima: Reciprocal regulation of LOX and LOXL2 expression during cell adhesion and terminal differentiation in epidermal keratinocytes. in Journal of dermatological science 2009 (PubMed)
    Zeige alle 3 Referenzen für 561690

  4. Human Polyclonal LOXL2 Primary Antibody für ELISA, WB - ABIN561689 : Ghiggeri, Gigante, Di Donato et al.: Constitutional Nephrin Deficiency in Conditionally Immortalized Human Podocytes Induced Epithelial-Mesenchymal Transition, Supported by β-Catenin/NF-kappa B Activation: A Consequence of Cell Junction ... in International journal of nephrology 2014 (PubMed)

  5. Human Polyclonal LOXL2 Primary Antibody für ICC, IF - ABIN442901 : Wong, Zhang, Gilkes, Chen, Wei, Chaturvedi, Hubbi, Semenza: Inhibitors of hypoxia-inducible factor 1 block breast cancer metastatic niche formation and lung metastasis. in Journal of molecular medicine (Berlin, Germany) 2012 (PubMed)

Weitere Antikörper gegen Lysyl Oxidase-Like 2 Interaktionspartner

Fruit Fly (Drosophila melanogaster) Lysyl Oxidase-Like 2 (LOXL2) Interaktionspartner

  1. Dmloxl-1 and Dmloxl-2 are differentially expressed; active DmLOXL-1 influences gene expression and development

Human Lysyl Oxidase-Like 2 (LOXL2) Interaktionspartner

  1. new LOXL2 splice variant contributes to tumor progression by novel molecular mechanisms different from LOXL2WT

  2. LOXL2 is a potential therapeutic target against tumor progression.

  3. Insulin (zeige INS Antikörper) resistance promotes lysyl oxidase like 2 induction and fibrosis accumulation in non-alcoholic fatty liver disease.

  4. SMYD3 (zeige SMYD3 Antikörper) enhances tumorigenicity in esophageal squamous cell carcinoma by enhancing transcription of ezrin (zeige EZR Antikörper) and LOXL2, which are involved in proliferation, migration, and invasion.

  5. Data show that lysyl oxidase-like 2 (LOXL2) is a histone modifier enzyme that removes trimethylated lysine 4 (K4) in histone H3 (zeige HIST3H3 Antikörper) (H3K4me3) through an amino-oxidase reaction.

  6. LOXL2 was determined to promote proliferation of hepatocellular carcinoma (HCC (zeige FAM126A Antikörper)) and demonstrated to be highly expressed in HCC (zeige FAM126A Antikörper) adjacent non-tumor tissue samples compared with tumor tissue samples.

  7. LOXL2 messenger RNA levels were increased in intrahepatic cholangiocarcinoma. These results were confirmed at a protein level, with a significantly higher LOXL2 immunostaining tumoral stroma. Univariate analysis revealed that LOXL2 expression was correlated with a poor overall survival and disease-free survival.

  8. glomerular extracellular matrix. Altogether, we demonstrate that LOXL2 is a novel component of the molecular machinery that forms cross-linked collagen IV (zeige COL4 Antikörper) networks, which are essential for glomerular basement membrane stability and molecular ultrafiltration function.

  9. The expression levels of lysyl oxidase-like 2 (LOXL2) mRNA and protein were markedly suppressed in transfected prostate cancer cells with microRNAs miR (zeige MLXIP Antikörper)-26a, miR (zeige MLXIP Antikörper)-26b, miR (zeige MLXIP Antikörper)-29a, miR (zeige MLXIP Antikörper)-29b, miR (zeige MLXIP Antikörper)-29c and miR (zeige MLXIP Antikörper)-218.

  10. Overexpression of LOXL2 and SERPINH1 (zeige SERPINH1 Antikörper) was observed in clinical specimens of lung cancer and fibrotic lesions. Downregulation of miR (zeige MLXIP Antikörper)-29a caused overexpression of LOXL2 and SERPINH1 (zeige SERPINH1 Antikörper) in lung cancer and IPF, suggesting that these genes are involved in the pathogenesis of these two diseases.

Mouse (Murine) Lysyl Oxidase-Like 2 (LOXL2) Interaktionspartner

  1. Insulin (zeige INS Antikörper) resistance promotes lysyl oxidase like 2 (zeige LOXL3 Antikörper) induction and fibrosis accumulation in non-alcoholic fatty liver disease.

  2. glomerular extracellular matrix. Altogether, we demonstrate that LOXL2 (zeige LOXL3 Antikörper) is a novel component of the molecular machinery that forms cross-linked collagen IV (zeige COL4 Antikörper) networks, which are essential for glomerular basement membrane stability and molecular ultrafiltration function.

  3. LOX (zeige LOX Antikörper) and LOXL2 (zeige LOXL3 Antikörper) may play an important role in the pathogenesis of AMD (zeige AMD1 Antikörper). Targeting LOXL2 (zeige LOXL3 Antikörper) could have a broader efficacy than targeting LOX (zeige LOX Antikörper), by reducing angiogenesis and inflammation, as well as fibrosis.

  4. Loss and gain of function analyses combined with in vivo studies in syngeneic breast cancer models demonstrate the participation of LOXL2 (zeige LOXL3 Antikörper) and E47 (zeige TCF3 Antikörper) in tumor growth and their requirement for lung metastasis.

  5. Findings reveal new insight into the mechanisms of fibroblast activation, a novel function of LOXL2 (zeige LOXL3 Antikörper), and further highlight the importance of generating LOXL2 (zeige LOXL3 Antikörper)-targeted therapies for the prevention of tumor progression and metastasis.

  6. The Snail1 (zeige SNAI1 Antikörper) transcription factor represses mouse pericentromeric transcription, acting through the H3K4 deaminase LOXL2 (zeige LOXL3 Antikörper).

  7. The enzymatic activity of lysyl oxidas-like-2 (LOXL2 (zeige LOXL3 Antikörper)) is not required for LOXL2 (zeige LOXL3 Antikörper)-induced inhibition of keratinocyte differentiation.

  8. This study provides the first evidence for the role of LOXL2 (zeige LOXL3 Antikörper) in regulating angiogenesis through collagen IV (zeige COL4 Antikörper) scaffolding.

  9. LOXL2 (zeige LOXL3 Antikörper) promotes chondrocyte differentiation by mechanisms that are likely to include roles as both a regulator and an effector of chondrocyte differentiation

  10. The efficacy and safety of LOXL2 (zeige LOXL3 Antikörper)-specific monoclonal antibody represents a new therapeutic approach with broad applicability in oncologic and fibrotic diseases.

Lysyl Oxidase-Like 2 (LOXL2) Antigen-Profil

Beschreibung des Gens

This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family.

Alternative names and synonyms associated with Lysyl Oxidase-Like 2 (LOXL2)

  • lysyl oxidase-like 2 (lox2) Antikörper
  • lysyl oxidase-like 2 (LOXL2) Antikörper
  • lysyl oxidase-like 2 (loxl2) Antikörper
  • lysyl oxidase-like 2 (Loxl2) Antikörper
  • 1110004B06Rik Antikörper
  • 4930526G11Rik Antikörper
  • 9430067E15Rik Antikörper
  • CG4402 Antikörper
  • Dmel\\CG4402 Antikörper
  • dmlox-2 Antikörper
  • Dmloxl-2 Antikörper
  • GB13360 Antikörper
  • LOR2 Antikörper
  • lox2-like Antikörper
  • loxl-2 Antikörper
  • LOXL2 Antikörper
  • WS9-14 Antikörper

Bezeichner auf Proteinebene für LOXL2

CG4402-PA , lox2-PA , lysyl oxidase-like 2 , Lysyl oxidase-like protein 2 , lysyl oxidase homolog 2 , lysyl oxidase homolog 2-like , lysyl oxidase related 2 , lysyl oxidase-like protein 2 , lysyl oxidase-related protein 2 , lysyl oxidase-related protein WS9-14 , Lysyl oxidase homolog 2

GENE ID SPEZIES
37485 Drosophila melanogaster
408544 Apis mellifera
585092 Strongylocentrotus purpuratus
100158339 Xenopus laevis
100216062 Xenopus (Silurana) tropicalis
100413360 Callithrix jacchus
464053 Pan troglodytes
710151 Macaca mulatta
100543026 Meleagris gallopavo
4017 Homo sapiens
419533 Gallus gallus
486118 Canis lupus familiaris
532684 Bos taurus
94352 Mus musculus
290350 Rattus norvegicus
100171427 Pongo abelii
Ausgewählte Anbieter für anti-Lysyl Oxidase-Like 2 (LOXL2) Antikörper
Haben Sie etwas anderes gesucht?