JDP2 Proteine (JDP2)

Jun Dimerization Protein 2 Proteine (JDP2)
Auf www.antikoerper-online.de finden Sie aktuell 8 Jun Dimerization Protein 2 (JDP2) Proteine von 4 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen JDP2 Antikörper (21) und JDP2 Kits (3) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 36 JDP2 Produkte verfügbar.
fk87c02, JDP2, Jundm2, Jundp2, TIF, wu:fk87c02, zgc:92851
alle Proteine anzeigen Gen GeneID UniProt
JDP2 122953 Q8WYK2
JDP2 81703 P97875
JDP2 116674 Q78E65

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Weitere Proteine zu JDP2 Interaktionspartnern

Human Jun Dimerization Protein 2 (JDP2) Interaktionspartner

  1. In hepatocellular carcinoma, high expression of JDP2 is significantly correlated with smaller tumor size, early stage HCC (zeige FAM126A Proteine) and better survival.

  2. Preeclamptic plasma induces transcription modifications involving the AP-1 (zeige FOSB Proteine) transcriptional regulator JDP2 in endothelial cells.

  3. Results suggest that JDP2 is an integral component of the Nrf2-MafK complex and that it modulates antioxidant and detoxification programs by acting via the ARE.

  4. the recruitment of multiple HDAC (zeige HDAC3 Proteine) members to JDP2 and ATF3 (zeige ATF3 Proteine) is part of their transcription repression mechanism.

  5. The molecular mechanisms that underlie the action of JDP2 in cellular aging and replicative senescence by mediating the dissociation of polycomb repressive complexes from the p16(Ink4a)/Arf locus are discussed.

  6. JDP2 is crucial to triggering reactivation from latency to lytic replication

  7. JDP2 expression was downregulated in pancreatic carcinoma & this correlated with metastasis & decreased post-surgery survival.

  8. c-Jun dimerization protein 2 inhibits cell transformation and has a role as a tumor suppressor gene

  9. JDP2 is a cellular survival protein whose presence is necessary for normal cellular function

  10. JDP2 acts as a repressor and could be functionally associated with HDAC3 (zeige HDAC3 Proteine) to inhibit CHOP (zeige DDIT3 Proteine) transcription

Mouse (Murine) Jun Dimerization Protein 2 (JDP2) Interaktionspartner

  1. Female JDP2 null mice, however, exhibited early puberty, observed as early vaginal opening, larger litters, and early reproductive senescence. JDP2 null females had increased levels of circulating FSH (zeige BRD2 Proteine) and higher expression of the Fshb (zeige FSHB Proteine) subunit in the pituitary, resulting in elevated serum estrogen and higher numbers of large ovarian follicles

  2. JDP2 acts as a novel transcriptional activator of the mouse Mc2r gene, suggesting that JDP2 may have physiological functions as a novel player in MC2R-mediated steroidogenesis as well as cell signaling in adrenal glands.

  3. High JDP2 expression in the bone marrow contributes to metastatic spread in the lung.

  4. results suggest a negative feedback loop between JDP2 and p53 (zeige TP53 Proteine), and a direct link between JDP2 and a key oncogenic pathway

  5. Tbx3 (zeige TBX3 Proteine) plays an important role in osteoclastogenesis at least in part by regulating CSF1 (zeige CSF1 Proteine)-dependent expression of JDP2.

  6. Using transgenic mice overexpressing the AP-1 (zeige JUN Proteine) inhibitor JDP2, a central role of AP-1 (zeige JUN Proteine) in the induction of hypertrophy and apoptosis in cardiomyocytes is demonstrated.

  7. Jdp2 transcriptionally regulates the Trp53 (zeige TP53 Proteine) promoter, via an atypical AP-1 (zeige JUN Proteine) site, and Jdp2 expression negatively regulates Trp53 (zeige TP53 Proteine) expression levels; a genetic mechanism for tumour formation in the context of Trp53 (zeige TP53 Proteine) heterozygosity

  8. the recruitment of multiple HDAC (zeige HDAC3 Proteine) members to JDP2 and ATF3 (zeige ATF3 Proteine) is part of their transcription repression mechanism.

  9. Jdp2 plays pivotal roles in in vivo bone homeostasis and host defense by regulating osteoclast and neutrophil differentiation.

  10. JDP2 phosphorylation by JNK (zeige MAPK8 Proteine) results in rapid JDP2 destabilization and reduced expression levels following various cell stimuli

Zebrafish Jun Dimerization Protein 2 (JDP2) Interaktionspartner

  1. the kinase fragment of DCLK (zeige DCLK2 Proteine) is translocated into the nucleus upon hyperosmotic stresses and the kinase efficiently phosphorylates JDP2, a possible target in the nucleus, with the aid of histones

JDP2 Protein Überblick

Protein Überblick

Component of the AP-1 transcription factor that represses transactivation mediated by the Jun family of proteins. Involved in a variety of transcriptional responses associated with AP-1 such as UV-induced apoptosis, cell differentiation, tumorigenesis and antitumogeneris. Can also function as a repressor by recruiting histone deacetylase 3/HDAC3 to the promoter region of JUN. May control transcription via direct regulation of the modification of histones and the assembly of chromatin.

Alternative names and synonyms associated with JDP2

  • Jun dimerization protein 2 (JDP2)
  • Jun dimerization protein 2 (Jdp2)
  • Jun dimerization protein 2 (jdp2)
  • fk87c02 Protein
  • JDP2 Protein
  • Jundm2 Protein
  • Jundp2 Protein
  • TIF Protein
  • wu:fk87c02 Protein
  • zgc:92851 Protein

Bezeichner auf Proteinebene für JDP2

Jun dimerization protein 2 , jun dimerization protein 2 , progesterone receptor co-activator , c-Jun dimerization protein 2

423363 Gallus gallus
453048 Pan troglodytes
531476 Bos taurus
122953 Homo sapiens
81703 Mus musculus
116674 Rattus norvegicus
436766 Danio rerio
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