HMGN1 Proteine (HMGN1)

Bezeichnung:
High Mobility Group Nucleosome Binding Domain 1 Proteine (HMGN1)
Auf www.antikoerper-online.de finden Sie aktuell 14 High Mobility Group Nucleosome Binding Domain 1 (HMGN1) Proteine von 8 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen HMGN1 Antikörper (101) und HMGN1 Kits (22) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 143 HMGN1 Produkte verfügbar.
Synonyme:
HMG-14, HMG14, hmgn1, hmgn1b
alle Proteine anzeigen Gen GeneID UniProt
HMGN1 15312 P18608
HMGN1 3150 P05114
Ratte HMGN1 HMGN1 360704  

Weitere Synonyme anzeigen

HMGN1 Proteine (HMGN1) nach Spezies

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Am meisten referenzierte HMGN1 Proteine

  1. Human HMGN1 Protein expressed in Escherichia coli (E. coli) - ABIN667774 : Landsman, McBride, Soares, Crippa, Srikantha, Bustin: Chromosomal protein HMG-14. Identification, characterization, and chromosome localization of a functional gene from the large human multigene family. in The Journal of biological chemistry 1989 (PubMed)

  2. Human HMGN1 Protein expressed in Wheat germ - ABIN1306822 : Mangé, Lacombe, Bascoul-Mollevi, Jarlier, Lamy, Rouanet, Maudelonde, Solassol: Serum autoantibody signature of ductal carcinoma in situ progression to invasive breast cancer. in Clinical cancer research : an official journal of the American Association for Cancer Research 2012 (PubMed)

Weitere Proteine zu HMGN1 Interaktionspartnern

Mouse (Murine) High Mobility Group Nucleosome Binding Domain 1 (HMGN1) Interaktionspartner

  1. Suggest Hmgn1/Cebpb (zeige CEBPB Proteine) signaling may play an important role during mouse decidualization.

  2. our findings show that HMGN1 contributes to antitumor immunity and it may offer an effective adjuvant to heighten responses to cancer vaccines.

  3. in mice, loss of HMGN1 leads to transcription changes that accelerate the progression of DEN-induced hepatocarcinogenesis, without affecting the type of tumors or the final total tumor burden of these mice.

  4. HMGN1 is a nucleosome remodeling protein encoded on chromosome 21q22 that suppresses H3K27me3 and promotes both B cell proliferation in vitro and B-ALL in vivo

  5. HMGN1 binds to CpG island-containing promoters and affects the organization of nucleosomes, DNase I (zeige DNASE1 Proteine) hypersensitivity, and the transcriptional profile of mouse embryonic stem cells and neural progenitors.

  6. Phenotypic analysis of Hmgn1(tm1/tm1 (zeige TPM2 Proteine)), Hmgn3 (zeige HMGN3 Proteine)(tm1/tm1 (zeige TPM2 Proteine)), and Hmgn5 (zeige HMGN5 Proteine)(tm1/tm1 (zeige TPM2 Proteine)) mice and their wild type littermates with a battery of standardized tests uncovered variant-specific abnormalities.

  7. a regulatory role for HMGN1 in PARP-1 (zeige PARP1 Proteine) activation.

  8. extracellular HMGN1 acts as a novel alarmin critical for LPS (zeige TLR4 Proteine)-induced development of innate and adaptive immune responses.

  9. HMGN1 regulates the expression of methyl CpG-binding protein 2 (MECP2 (zeige MECP2 PLURAL_@35191@)) in mouse and human, and affects the behavior of mice

  10. Regulation of Hmgn1 and Fgf18 (zeige FGF18 Proteine) at the digit-interdigit junction suggests retinoic acid controls tissue remodeling as well as apoptosis.

Human High Mobility Group Nucleosome Binding Domain 1 (HMGN1) Interaktionspartner

  1. RNA-seq evidence of biallelic expression of HMGN1 and 10 neighboring genes in at least one primary human tissue tested indicates that the expression of HMGN1 is uncoupled from the control of the maternally inherited 5mCpG imprints at the WRB (zeige WRB Proteine) differentially methylated region (DMR (zeige WDR20 Proteine)) in disomic controls or trisomy (Down syndrome) individuals.

  2. HMGN1 can serve as a useful clinical parameter for evaluating disease progression and predicting the outcomes for early-stage patients with non-small cell lung cancer .

  3. nucleosome binding protein HMGN1 as a new PCNA (zeige PCNA Proteine)-interacting protein that enhances the binding of PCNA (zeige PCNA Proteine) to chromatin

  4. extracellular HMGN1 acts as a novel alarmin critical for LPS (zeige IRF6 Proteine)-induced development of innate and adaptive immune responses.

  5. HMGN1 regulates the expression of methyl CpG-binding protein 2 (MECP2 (zeige MECP2 PLURAL_@35191@)) in mouse and human, and affects the behavior of mice

  6. HMGN1 is not randomly distributed throughout the genome. Instead, the protein preferentially localizes to DNase I (zeige DNASE1 Proteine) hypersensitive (HS) sites, promoters, functional enhancers, and transcription factor binding sites.

  7. Results show that four serine residues, i.e., Ser6, Ser85, Ser88, and Ser98, can be phosphorylated in high mobility group (zeige SSRP1 Proteine) N1 (HMGN1).

  8. HMGN1 optimizes the cellular response to ionizing radiation and to other tumorigenic events; therefore, loss of this protein increases the tumor burden in mice.

  9. SWI (zeige SMARCA1 Proteine)/SNF (zeige SNRPA Proteine) functions independently of HMGN1

  10. Five serine residues, i.e., Ser6, Ser7, Ser85, Ser88, and Ser98, in HMGN1 can be phosphorylated by the kinase in vitro, and Ser6, Ser7, and Ser85 were new sites among these five sites.

HMGN1 Protein Überblick

Protein Überblick

The protein encoded by this gene binds nucleosomal DNA and is associated with transcriptionally active chromatin. Along with a similar protein, HMG17, the encoded protein may help maintain an open chromatin configuration around transcribable genes.

Alternative names and synonyms associated with HMGN1

  • high mobility group nucleosome binding domain 1 (hmgn1-b)
  • high mobility group nucleosome binding domain 1 (hmgn1)
  • high-mobility group nucleosome binding domain 1 (HMGN1)
  • high mobility group nucleosomal binding domain 1 (Hmgn1)
  • high mobility group nucleosome binding domain 1 (HMGN1)
  • high mobility group nucleosome binding domain 1 (Hmgn1)
  • high-mobility group nucleosome binding domain 1 (LOC100350031)
  • HMG-14 Protein
  • HMG14 Protein
  • hmgn1 Protein
  • hmgn1b Protein

Bezeichner auf Proteinebene für HMGN1

high-mobility group nucleosome binding domain 1 b , high-mobility group nucleosome binding domain 1 , non-histone chromosomal protein HMG-14 , high mobility group nucleosome-binding domain-containing protein 1 , high mobility group protein 14 , high-mobility group nucleosome-binding domain-containing protein 1 , HMG-14 protein , non-histone chromosomal protein HMG-14B , high-mobility group (nonhistone chromosomal) protein 14 , high-mobility group nucleosome binding 1 , nonhistone chromosomal protein HMG-14

GENE ID SPEZIES
380456 Xenopus laevis
394660 Xenopus (Silurana) tropicalis
100137463 Papio anubis
15312 Mus musculus
395999 Gallus gallus
3150 Homo sapiens
785479 Bos taurus
360704 Rattus norvegicus
100328653 Oryctolagus cuniculus
100725547 Cavia porcellus
614915 Bos taurus
100350031 Oryctolagus cuniculus
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