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Suggest Hmgn1/Cebpb (zeige CEBPB ELISA Kits) signaling may play an important role during mouse decidualization.
our findings show that HMGN1 contributes to antitumor immunity and it may offer an effective adjuvant to heighten responses to cancer vaccines.
in mice, loss of HMGN1 leads to transcription changes that accelerate the progression of DEN-induced hepatocarcinogenesis, without affecting the type of tumors or the final total tumor burden of these mice.
HMGN1 is a nucleosome remodeling protein encoded on chromosome 21q22 that suppresses H3K27me3 and promotes both B cell proliferation in vitro and B-ALL in vivo
HMGN1 binds to CpG island-containing promoters and affects the organization of nucleosomes, DNase I (zeige DNASE1 ELISA Kits) hypersensitivity, and the transcriptional profile of mouse embryonic stem cells and neural progenitors.
Phenotypic analysis of Hmgn1(tm1/tm1 (zeige TPM2 ELISA Kits)), Hmgn3 (zeige HMGN3 ELISA Kits)(tm1/tm1 (zeige TPM2 ELISA Kits)), and Hmgn5 (zeige HMGN5 ELISA Kits)(tm1/tm1 (zeige TPM2 ELISA Kits)) mice and their wild type littermates with a battery of standardized tests uncovered variant-specific abnormalities.
a regulatory role for HMGN1 in PARP-1 (zeige PARP1 ELISA Kits) activation.
extracellular HMGN1 acts as a novel alarmin critical for LPS (zeige TLR4 ELISA Kits)-induced development of innate and adaptive immune responses.
HMGN1 regulates the expression of methyl CpG-binding protein 2 (MECP2) in mouse and human, and affects the behavior of mice
Regulation of Hmgn1 and Fgf18 (zeige FGF18 ELISA Kits) at the digit-interdigit junction suggests retinoic acid controls tissue remodeling as well as apoptosis.
HMGN1 and HMGN 2 (zeige HMGN2 ELISA Kits) remodel core and linker histone tail domains within chromatin.
RNA-seq evidence of biallelic expression of HMGN1 and 10 neighboring genes in at least one primary human tissue tested indicates that the expression of HMGN1 is uncoupled from the control of the maternally inherited 5mCpG imprints at the WRB (zeige WRB ELISA Kits) differentially methylated region (DMR (zeige WDR20 ELISA Kits)) in disomic controls or trisomy (Down syndrome) individuals.
HMGN1 can serve as a useful clinical parameter for evaluating disease progression and predicting the outcomes for early-stage patients with non-small cell lung cancer .
nucleosome binding protein HMGN1 as a new PCNA (zeige PCNA ELISA Kits)-interacting protein that enhances the binding of PCNA (zeige PCNA ELISA Kits) to chromatin
extracellular HMGN1 acts as a novel alarmin critical for LPS (zeige IRF6 ELISA Kits)-induced development of innate and adaptive immune responses.
HMGN1 is not randomly distributed throughout the genome. Instead, the protein preferentially localizes to DNase I (zeige DNASE1 ELISA Kits) hypersensitive (HS) sites, promoters, functional enhancers, and transcription factor binding sites.
Results show that four serine residues, i.e., Ser6, Ser85, Ser88, and Ser98, can be phosphorylated in high mobility group (zeige SSRP1 ELISA Kits) N1 (HMGN1).
HMGN1 optimizes the cellular response to ionizing radiation and to other tumorigenic events; therefore, loss of this protein increases the tumor burden in mice.
SWI (zeige SMARCA1 ELISA Kits)/SNF (zeige SNRPA ELISA Kits) functions independently of HMGN1
The protein encoded by this gene binds nucleosomal DNA and is associated with transcriptionally active chromatin. Along with a similar protein, HMG17, the encoded protein may help maintain an open chromatin configuration around transcribable genes.
high-mobility group nucleosome binding domain 1 b
, high-mobility group nucleosome binding domain 1
, non-histone chromosomal protein HMG-14
, high mobility group nucleosome-binding domain-containing protein 1
, high mobility group protein 14
, high-mobility group nucleosome-binding domain-containing protein 1
, HMG-14 protein
, non-histone chromosomal protein HMG-14B
, high-mobility group (nonhistone chromosomal) protein 14
, high-mobility group nucleosome binding 1
, nonhistone chromosomal protein HMG-14