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Human FOXP3 ELISA Kit für Sandwich ELISA - ABIN417287
Eleftheriadis, Pissas, Karioti, Antoniadi, Antoniadis, Liakopoulos, Stefanidis: Dichloroacetate at therapeutic concentration alters glucose metabolism and induces regulatory T-cell differentiation in alloreactive human lymphocytes. in Journal of basic and clinical physiology and pharmacology 2013
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analysis of Foxp3-based immunoregulation and autoimmunity in zebrafish
correlation between the expression of t-bet, stat6 (zeige STAT6 ELISA Kits) and foxp3 with other genes involved in Th and T(reg (zeige KCNH2 ELISA Kits)) responses
cloning and characterization of the full-length cDNA of Atlantic salmon Foxp3, which possesses a Forkhead domain, a zinc finger domain and a leucine-zipper domain as its counterpart in mammals
Results show that the positive rates and expression levels of nestin (zeige NES ELISA Kits), tyrosine hydroxylase (TH (zeige TH ELISA Kits)), GFAP (zeige GFAP ELISA Kits) and IL-17 (zeige IL17A ELISA Kits) were significantly decreased while Foxp3 and the ratio of Foxp3/IL-17 (zeige IL17A ELISA Kits) were statistically elevated in BM of AML (zeige RUNX1 ELISA Kits) patients.
FOXP3-positive gastric adenocarcinoma patients had significantly increased overall survival and disease-free survival rates. p21 (zeige CDKN1A ELISA Kits) expression showed a significant positive correlation with tumoral FOXP3 expression in gastric adenocarcinoma cells.
These results underline the particular genetic background of the Tunisian endemic PF and suggest the implication of FOXP3 gene in the susceptibility and the clinical course of the disease.
this study shows that abnormal expression of miR (zeige MLXIP ELISA Kits)-125a-5p and its effect on foxp3 expression are likely involved in the pathogenesis of thymoma-associated myasthenia gravis
both FOXP3 rs5902434 genotypes and alleles were differently distributed in COPD (zeige ARCN1 ELISA Kits) patients and smokers with normal lung function. The distribution of del/del genotype was associated with systemic expression ofFOXP3mRNA
FOXP3 overexpression promoted cell proliferation, migration, and invasion in increased TGF-beta (zeige TGFB1 ELISA Kits) expression and secretion in gastric cancer cells, while FOXP3 knockdown suppressed these effects.
Postoperative increases in Foxp3+T and Tr1 cells may predict the risk of early recurrence in digestive system neoplasms.
Elevated Foxp3 protein expression was a predictive factor of outcome in oral squamous cell carcinoma and could act as a promising therapeutic target.
a possible link and synergistic role of Foxp3 and TLR4 (zeige TLR4 ELISA Kits) in promoting the immune escape of cervical cancer.
FOXP3 expression was most potently induced by tumours secreting higher levels of total and active TGFbeta1 (zeige TGFB1 ELISA Kits) and this induction could be potently counteracted with IL-21 (zeige IL17C ELISA Kits), restoring T cell proliferation.
Mechanistic analysis indicated that E47 (zeige TCF3 ELISA Kits) activated expression of the transcription factor Spi-B (zeige SPIB ELISA Kits) and the suppressor of cytokine signaling 3 (SOCS3 (zeige SOCS3 ELISA Kits)), which both downregulated Foxp3 expression. These findings demonstrate that the balance of Id3 (zeige ID3 ELISA Kits) and E47 (zeige TCF3 ELISA Kits) controls the maintenance of Foxp3 expression in Treg cells and, thus, contributes to Treg cell plasticity.
Foxp3 expression in lung epithelial cells, and not in Treg cells, inhibited OVA- and cockroach extract-induced asthma.
Regulatory T cells have a high apoptosis rate ex vivo correlating with low c-FLIP (zeige CFLAR ELISA Kits) expression.
Forkhead box P3 protein (zeige SLC10A3 ELISA Kits) (FoxP3) acts in multimodal fashion to directly activate or repress transcription, in a context- and partner-dependent manner, to govern Treg cell phenotypes.
Membrane-bound DKK-1 (zeige DKK1 ELISA Kits) is a novel Foxp3 postive Treg cell derived mediator to maintain immunological tolerance in T-cell-mediated autoimmune colitis.
A384T mutation associated with autoimmune IPEX syndrome, induces a distinctive tissue-restricted inflammation by specifically impairing the ability of Treg cells to compete with pathogenic T cells
Systemic NRF2 (zeige NFE2L2 ELISA Kits) activation by Keap1 (zeige KEAP1 ELISA Kits) knockdown alleviates multiple-organ inflammation and improves the survival rate of Sf mice.
CTLA-4 (zeige CTLA4 ELISA Kits) expressed by FOXP3(+) regulatory T cells prevents inflammatory tissue attack and not T-cell priming in arthritis.
Inhibition of IL-27p28 also enhanced the suppressive capacity of adoptively transferred CD4 (zeige CD4 ELISA Kits)(+) nTregs by increasing the stability of Foxp3 expression.
This study suggests that the epigenetic modification of FOXP3 gene is involved in the pathogenesis of EAE.
sequenced the entire Foxp3 cDNA which is 1296 nucleotides in length and codes for a polypeptide of 432 amino acids
In a miniature swine lung transplantation model, the FOXP3 mRNA level in the peripheral blood was upregulated at an early phase of rejection
Experimental infection with bovine viral diarrhea virus did not provide evidence ofTreg activation based on expression of FoxP3 and CTLA4 (zeige CTLA4 ELISA Kits).
The expression of Foxp3 in CD4 (zeige CD4 ELISA Kits)(+) T cells from persistent lymphocytotic cattle was significantly increased.
There is a positive correlation between the intensity of CD25 (zeige IL2RA ELISA Kits) expression and the expression of the transcription Foxp3 factor in bovine CD8 (zeige CD8A ELISA Kits)(+) cells.
identification of Foxp3 expression in Treg cells
These findings revealed that despite the existence of a distinct bovine CD4 (zeige CD4 ELISA Kits)(+)CD25 (zeige IL2RA ELISA Kits)(high) T cell population, which showed Foxp3 transcription/expression, natural regulatory activity did not reside in this cell population
The correlation of TH17-related TLR4 (zeige TLR4 ELISA Kits) expression and Foxp3-positive cells in the rectal tissue of horses with inflammatory bowel disease is reported.
Expression levels of FOXP3 mRNA copy numbers were significantly increased in lesional compared to tumour-distant samples. There was no difference in FOXP3 expression in tumour-distant samples from equine sarcoid- compared with control horses.
results confirm FoxP3 expression in the horse, in contrast to the mouse, is regulated similarly to FOXP3 expression in humans and provide evidence that FoxP3 expression by conventional T cells may help regulate the developing immune response
The protein encoded by this gene is a member of the forkhead/winged-helix family of transcriptional regulators. Defects in this gene are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX), also known as X-linked autoimmunity-immunodeficiency syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.
forkhead box protein P3
, regulatory protein Foxp3
, forkhead box P3
, forkhead box protein P3-like
, transcription factor foxp3
, immune dysregulation, polyendocrinopathy, enteropathy, X-linked
, immunodeficiency, polyendocrinopathy, enteropathy, X-linked
, forkhead/winged helix transcription factor 3