anti-Human Zinc Finger Protein 163 Antikörper für Immunofluorescence (Paraffin-embedded Sections)

Recommended Zinc Finger Protein 163 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Zinc Finger Protein 163 (ZNF163) Antikörper
  • AW495828
  • Gfi-1
  • Pal-1
  • Pal1
  • GFI-1
  • GFI1A
  • SCN2
  • ZNF163
  • growth factor independent 1
  • growth factor independent 1 transcription repressor
  • Gfi1
  • GFI1
Reaktivität
Human, Maus, Ratte (Rattus)
60
15
13
9
5
4
4
3
3
3
1
Wirt
Kaninchen
36
24
Klonalität
Polyklonal
Konjugat
Unkonjugiert
1
1
1
1
1
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
58
27
13
11
6
6
1
Optionen
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Produktnummer ABIN1714623
$ 295.90
Zzgl. Versandkosten $45.00

General

Antigen Zinc Finger Protein 163 (ZNF163) Antikörper
Reaktivität Human, Maus, Ratte (Rattus)
(60), (15), (13), (9), (5), (4), (4), (3), (3), (3), (1)
Wirt Kaninchen
(36), (24)
Klonalität
Polyklonal
Konjugat Unkonjugiert
(1), (1), (1), (1), (1), (1)
Applikation Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(58), (27), (13), (11), (6), (6), (1)
Hersteller Anmelden zum Anzeigen

Produktdetails

Antigendetails Anwendungsinformationen Handhabung Bilder
Reinigung Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human GFI1/ZNF163
Isotyp IgG

Antigendetails

Produktdetails Anwendungsinformationen Handhabung Bilder zurück nach oben
Antigen
Andere Bezeichnung Gfi1/Znf163 (ZNF163 Antibody Abstract)
Hintergrund

Growth factor independent 1 (Gfi-1) is a transcriptional repressor that specifically binds to the DNA consensus sequence TAAATCAC(A/T)GCA. The carboxy-terminus of Gfi-1 contains six C2H2-type zinc finger motifs, and zinc fingers 3, 4 and 5 are required for the binding of Gfi-1 to its DNA binding site. Gfi-1 also contains a 20 amino acid SNAG domain which mediates transcriptional repression. It represses Bax at the mRNA and protein levels, resulting in the inhibition of cell death. Gfi1 is expressed outside the lymphoid system in granulocytes and activated macrophages. Gfi-1B, a related protein, is a transcriptional repressor primarily expressed in bone marrow and spleen. Gfi-1B is a direct repressor of the p21 promoter and the Socs 1 and 3 promoters. The genes encoding human Gfi-1 and Gfi-1B map to chromosome 1p22 and 9q34.3, respectively.

Synonyms: GFI 1, GFI1, GFI-1, GFI1_HUMAN, Growth factor independence 1, growth factor independent 1, Growth factor independent protein 1, SCN2, Zinc finger protein 163, Zinc finger protein Gfi 1, Zinc finger protein Gfi-1, Zinc finger protein Gfi1, ZNF 163, ZNF163.

Gen-ID 2672
Pathways Cellular Response to Molecule of Bacterial Origin

Anwendungsinformationen

Produktdetails Antigendetails Handhabung Bilder zurück nach oben
Applikationshinweise WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails Antigendetails Anwendungsinformationen Bilder zurück nach oben
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C
Haltbarkeit 12 months