Use your antibodies-online credentials, if available.
Keine Produkte auf Ihrer Vergleichsliste.
Ihr Warenkorb ist leer.
Weitere Synonyme anzeigen
Wählen Sie die gewünschte Spezies
Human VLDLR Protein expressed in Human Cells - ABIN2003915
Trommsdorff, Gotthardt, Hiesberger, Shelton, Stockinger, Nimpf, Hammer, Richardson, Herz: Reeler/Disabled-like disruption of neuronal migration in knockout mice lacking the VLDL receptor and ApoE receptor 2. in Cell 1999
Zeige alle 5 Referenzen für ABIN2003915
The presence of reelin (zeige RELN Proteine) was elevated in junctional areas as in dysplastic nevi. VLDLR presented positive values in 16 cases (16/ 32) and ApoER2 (zeige LRP8 Proteine) was weak positive in 7 cases.
These results for the first time demonstrated that SalA protected against IS/RP-induced endothelial barrier dysfunction through suppression of VLDL receptor expression
these results suggest that VLDLR functions in vivo as an HCV receptor independent of canonical CD81 (zeige CD81 Proteine)-mediated HCV entry.
the results obtained indicate that minimal fibrin-binding structures are located within the second and third CR domains of the VLDL receptor and the presence of the fourth CR domain is required for high-affinity binding
The results of this study demonstrated the presence of reelin (zeige RELN Proteine), its receptors VLDLR and ApoER2 (zeige LRP8 Proteine) as well as Dab1 (zeige DAB1 Proteine) in the ENS and might indicate a novel role of the reelin (zeige RELN Proteine) system in regulating neuronal plasticity and pre-synaptic functions in the ENS.
these results suggested that the miR (zeige MLXIP Proteine)-135a-VLDLR-p38 (zeige CRK Proteine) axis may contribute to gallbladder cancer cell proliferation
study identified a novel homozygous VLDLR c.2248C>T mutation (p.Q750X) and distinctive MRI (zeige C7ORF49 Proteine) findings in 2 siblings with ataxia (zeige USP14 Proteine); also marked vitamin E deficiency was detected in the proband
these results identify a novel role for the VLDLR as a negative regulator of DC-mediated adaptive immune responses in HDM (zeige HDAC3 Proteine)-induced allergic airway inflammation.
ectopic expression of HIC1 (zeige HIC1 Proteine) in U2OS and MDA-MB-231 cell lines decreases expression of the ApoER2 (zeige LRP8 Proteine) and VLDLR genes, encoding two canonical tyrosine kinase (zeige TXK Proteine) receptors for Reelin (zeige RELN Proteine).
an unusual constellation of VLDLR mutations in Cerebellar ataxia (zeige USP14 Proteine), mental retardation and dysequilibrium syndrome 1 is reported
Study showed that the two major VLDLR splice variants have differential activities in regulating Wnt (zeige WNT2 Proteine) signaling due to their different ectodomain shedding rates, which identified the functional difference of these splice variants.
The absence of PCSK9 (zeige PCSK9 Proteine) results in a sex- and tissue-specific subcellular distribution of the LDLR (zeige LDLR Proteine) and VLDLR, which is determined by estradiol levels.
In the retinas of Vldlr(-/-) mice with low fatty acid uptake but high circulating lipid levels, we found that Ffar1 suppresses expression of the glucose transporter Glut1 (zeige SLC2A1 Proteine)
neuronal stress differentially regulates lipoprotein receptor expression in neurons, with VLDLR upregulation as a common element as a modulator of neuronal Wnt (zeige WNT2 Proteine) signaling
Subretinal vascularization (SRV) in the Vldlr-/- model is associated with mistargeted neurites and that SRV is preceded by altered retinal vascular development.
VLDLR requires RasGRF1 (zeige RASGRF1 Proteine)/CaMKII (zeige CAMK2G Proteine) to alter dendritic spine formation.
This study demonstrated that VLDLR is expressed in distinct spatiotemporal patterns in developing mouse cerebral cortex.
LRP5 (zeige LRP5 Proteine) signaling is a prerequisite for neovascularization in VLDLR knockout mice. LRP5 (zeige LRP5 Proteine) may be an effective target for inhibiting intraretinal neovascularization.
Nuclear factor (erythroid-derived 2)-like 2 (zeige NFE2L2 Proteine) activation-induced hepatic very-low-density lipoprotein receptor overexpression in response to oxidative stress contributes to alcoholic liver disease in mice.
The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. This gene encodes a lipoprotein receptor that is a member of the LDLR family and plays important roles in VLDL-triglyceride metabolism and the reelin signaling pathway. Mutations in this gene cause VLDLR-associated cerebellar hypoplasia. Alternative splicing generates multiple transcript variants encoding distinct isoforms for this gene.
, very low-density lipoprotein receptor
, VTG receptor
, very low density lipoprotein (VLDL)/vitellogenin receptor
, vitellogenin receptor