anti-Maus Selenoprotein S Antikörper für Western Blotting

Recommended Selenoprotein S Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Selenoprotein S (SELS) Antikörper
  • ADO15
  • SBBI8
  • SELS
  • SEPS1
  • 1500011E07Rik
  • C78786
  • H-4
  • H-47
  • H4
  • H47
  • Sels
  • sg2
  • VCP-interacting membrane protein
  • VIMP
  • Vimp
Epitop
Middle Region
11
5
1
1
1
1
1
1
Reaktivität
Rind (Kuh), Hund, Ziege, Meerschweinchen, Pferd, Human, Maus, Kaninchen, Ratte (Rattus), Yeast, Zebrafisch
45
25
24
1
1
Wirt
Kaninchen
36
8
Klonalität
Polyklonal
Konjugat
Unkonjugiert
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Western Blotting (WB)
29
13
11
8
5
5
4
4
1
Optionen
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Bilder

Produktnummer ABIN2783218
$ 289.00
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
3.2182703 ABIN4352486 ICC IF IHC IHC (p) WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 3
1 ABIN727184 IHC (p) WB HRP Rabbit IgG Anmelden zum Anzeigen Polyclonal
1 ABIN727177 IHC (p) WB Biotin Rabbit IgG Anmelden zum Anzeigen Polyclonal
1 ABIN727175 IF (p) IHC (p) WB Rabbit IgG Anmelden zum Anzeigen Polyclonal
1 ABIN1585194 IHC ELISA WB Rabbit N-Term Anmelden zum Anzeigen Polyclonal
1 ABIN1092093 ELISA WB Rabbit IgG Anmelden zum Anzeigen Polyclonal
1 ABIN1092094 ELISA WB Rabbit IgG Anmelden zum Anzeigen Polyclonal
1 ABIN3059827 IP WB Rabbit Anmelden zum Anzeigen Polyclonal

General

Antigen Selenoprotein S (SELS) Antikörper
Epitop Middle Region
(11), (5), (1), (1), (1), (1), (1), (1)
Reaktivität Rind (Kuh), Hund, Ziege, Meerschweinchen, Pferd, Human, Maus, Kaninchen, Ratte (Rattus), Yeast, Zebrafisch
(45), (25), (24), (1), (1)
Wirt Kaninchen
(36), (8)
Klonalität
Polyklonal
Konjugat Unkonjugiert
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Western Blotting (WB)
(29), (13), (11), (8), (5), (5), (4), (4), (1)
Pubmed 3 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails

Antigendetails Anwendungsinformationen Handhabung Referenzen Bilder
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN983517.
Sequenz PDVVVKRQEA LAAARLKMQE ELNAQVEKHK EKLKQLEEEK RRQKIEMWDS
Homologie Cow: 93%, Dog: 86%, Goat: 75%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 92%, Rat: 93%, Yeast: 90%, Zebrafish: 100%
Produktmerkmale This is a rabbit polyclonal antibody against SELS. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human SELS

Antigendetails

Produktdetails Anwendungsinformationen Handhabung Referenzen Bilder zurück nach oben
Antigen
Andere Bezeichnung SELS (SELS Antibody Abstract)
Hintergrund SELS is a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Studies suggest that this protein may regulate cytokine production, and thus play a key role in the control of the inflammatory response.This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Studies suggest that this protein may regulate cytokine production, and thus play a key role in the control of the inflammatory response. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.
Alias Symbols: AD-015, ADO15, MGC104346, MGC2553, SBBI8, SEPS1, VIMP, SELS
Protein Interaction Partner: UBC, SRPK2, PTGS2, CAV1, DERL2, APOB, DERL1, VCP, KPNB1, AMFR, SYVN1, HERPUD1, SAA1, SVIP, NPLOC4, UFD1L, HSPA4,
Protein Size: 189
Molekulargewicht 21 kDa
Gen-ID 55829
NCBI Accession NM_018445, NP_060915
UniProt Q9BQE4
Pathways Cellular Response to Molecule of Bacterial Origin, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Cell RedoxHomeostasis, Negative Regulation of intrinsic apoptotic Signaling

Anwendungsinformationen

Produktdetails Antigendetails Handhabung Referenzen Bilder zurück nach oben
Applikationshinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 189 AA

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

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Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen

Produktdetails Antigendetails Anwendungsinformationen Handhabung Bilder zurück nach oben
Produkt verwendet in:

Du, Liu, Huang: "Influence of SelS gene silence on beta-Mercaptoethanol-mediated endoplasmic reticulum stress and cell apoptosis in HepG2 cells." in: Biochimica et biophysica acta, Vol. 1800, Issue 5, pp. 511-7, 2010

Moses, Johnson, Tømmerdal, Forsmo, Curran, Abraham, Charlesworth, Brennecke, Blangero, Austgulen: "Genetic association of preeclampsia to the inflammatory response gene SEPS1." in: American journal of obstetrics and gynecology, Vol. 198, Issue 3, pp. 336.e1-5, 2008

Zeng, Du, Zhou, Huang: "Role of SelS in lipopolysaccharide-induced inflammatory response in hepatoma HepG2 cells." in: Archives of biochemistry and biophysics, Vol. 478, Issue 1, pp. 1-6, 2008

Bilder

Produktdetails Antigendetails Anwendungsinformationen Handhabung Referenzen zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-Selenoprotein S (SELS) (Middle Region) antibody (ABIN2783218) WB Suggested Anti-SELS Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive...