anti-Human Metadherin Antikörper für Enzyme Immunoassay

Recommended Metadherin Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Metadherin (MTDH) Antikörper
  • MGC75963
  • 2610103J23Rik
  • 3D3
  • 3D3/Lyric
  • AEG-1
  • AV353288
  • D8Bwg1112e
  • Lyric
  • AEG1
  • LYRIC
  • LYRIC/3D3
  • metadherin
  • mtdh
  • MTDH
  • Mtdh
Reaktivität
Human
101
34
30
3
1
1
1
1
1
Wirt
Maus
57
43
3
Klonalität
Monoklonal
Konjugat
Unkonjugiert
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
88
46
35
34
27
13
11
6
5
1
1
1
1
Hersteller
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Hersteller Produkt- Nr.
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Bilder

Produktnummer ABIN1108306
$ 390.50
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN1108307 EIA IHC (fro) WB Rabbit N-Term Anmelden zum Anzeigen Polyclonal

General

Antigen Metadherin (MTDH) Antikörper
Reaktivität Human
(101), (34), (30), (3), (1), (1), (1), (1), (1)
Wirt Maus
(57), (43), (3)
Klonalität (Klon)
Monoklonal   ( )
Konjugat Unkonjugiert
(2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(88), (46), (35), (34), (27), (13), (11), (6), (5), (1), (1), (1), (1)
Hersteller Anmelden zum Anzeigen

Produktdetails

Antigendetails Anwendungsinformationen Handhabung Bilder
Spezifität This antibody reacts to Metadherin.
Kreuzreaktivität (Details) Species reactivity (tested):Human.
Reinigung Affinity chromatography on Protein G
Klon 2F11C3
Isotyp IgG1

Antigendetails

Produktdetails Anwendungsinformationen Handhabung Bilder zurück nach oben
Antigen
Andere Bezeichnung MTDH (MTDH Antibody Abstract)
Hintergrund Metadherin (Metastasis adhesion protein), also known as MTDH, LYsine-RIch CEACAM1 co-isolated (LYRIC), is a novel protein that localizes with the tight junction proteins ZO-1 and occludin in polarized epithelial cells. At the tight junction, it acts not as a structural component, but is rather recruited during the maturation of the tight junction complex. Metadherin is overexpressed in breast cancer tissue and breast tumor xenografts, while much lower levels are expressed in normal breast tissue. Metadherin binds to lung vasculature, one of the four common sites of breast cancer metastasis, through a C-terminal segment in the extracellular domain, blocking this lung-homing domain with antibodies or inhibiting metadherin with siRNA has been reported to inhibit breast cancer metastasis.Synonyms: 3D3/LYRIC, AEG-1, AEG1, Astrocyte elevated gene-1 protein, LYRIC, Lysine-rich CEACAM1 co-isolated protein, Metadherin, Metastasis adhesion protein
Molekulargewicht 64 kDa
Gen-ID 92140
Pathways Cellular Response to Molecule of Bacterial Origin, Cell-Cell Junction Organization

Anwendungsinformationen

Produktdetails Antigendetails Handhabung Bilder zurück nach oben
Applikationshinweise Optimal working dilution should be determined by the investigator.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails Antigendetails Anwendungsinformationen Bilder zurück nach oben
Format Liquid
Buffer PBS, 0,03 % sodium azide, 50 % glycerol
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Bilder

Produktdetails Antigendetails Anwendungsinformationen Handhabung zurück nach oben
Bilder des Herstellers
Immunohistochemistry (IHC) image for anti-Metadherin (MTDH) antibody (ABIN1108306) anti-Metadherin (MTDH) antibody
Flow Cytometry (FACS) image for anti-Metadherin (MTDH) antibody (ABIN1108306) anti-Metadherin (MTDH) antibody (Image 2)
Western Blotting (WB) image for anti-Metadherin (MTDH) antibody (ABIN1108306) anti-Metadherin (MTDH) antibody (Image 3)