anti-Ratte (Rattus) Leukotriene C4 Synthase Antikörper für Western Blotting

Recommended Leukotriene C4 Synthase Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Leukotriene C4 Synthase (LTC4S) Antikörper
  • LTC4S
  • ltc4s
  • leukotriene C4 synthase
  • leukotriene C4 synthase, gene 1
  • LTC4S
  • ltc4s.1
  • Ltc4s
Epitop
N-Term
24
4
1
Reaktivität
Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Kaninchen, Ratte (Rattus), Zebrafisch
27
3
3
3
3
2
2
2
1
1
1
1
Wirt
Kaninchen
27
Klonalität
Polyklonal
Konjugat
Unkonjugiert
2
2
2
2
2
2
Applikation
Western Blotting (WB)
25
16
1
Optionen
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Bilder

Produktnummer ABIN2783616
$ 229.00
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
3.1181145 ABIN2783615 WB Rabbit N-Term Anmelden zum Anzeigen Polyclonal

General

Antigen Leukotriene C4 Synthase (LTC4S) Antikörper
Epitop N-Term
(24), (4), (1)
Reaktivität Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Kaninchen, Ratte (Rattus), Zebrafisch
(27), (3), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1)
Wirt Kaninchen
(27)
Klonalität
Polyklonal
Konjugat Unkonjugiert
(2), (2), (2), (2), (2), (2)
Applikation Western Blotting (WB)
(25), (16), (1)
Pubmed 2 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails

Antigendetails Anwendungsinformationen Handhabung Referenzen Bilder
Sequenz MKDEVALLAA VTLLGVLLQA YFSLQVISAR RAFRVSPPLT TGPPEFERVY
Homologie Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 92%, Rabbit: 93%, Rat: 92%, Zebrafish: 85%
Produktmerkmale This is a rabbit polyclonal antibody against LTC4S. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Protein A purified
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human LTC4S

Antigendetails

Produktdetails Anwendungsinformationen Handhabung Referenzen Bilder zurück nach oben
Antigen
Andere Bezeichnung LTC4S (leukotriene C4 synthase) (LTC4S) (LTC4S Antibody Abstract)
Hintergrund The MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) family includes a number of human proteins, several of which are involved the production of leukotrienes. LTC4S is an enzyme that catalyzes the first step in the biosynthesis of cysteinyl leukotrienes, potent biological compounds derived from arachidonic acid. Leukotrienes have been implicated as mediators of anaphylaxis and inflammatory conditions such as human bronchial asthma.The MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) family includes a number of human proteins, several of which are involved the production of leukotrienes. This gene encodes an enzyme that catalyzes the first step in the biosynthesis of cysteinyl leukotrienes, potent biological compounds derived from arachidonic acid. Leukotrienes have been implicated as mediators of anaphylaxis and inflammatory conditions such as human bronchial asthma. This protein localizes to the nuclear envelope and adjacent endoplasmic reticulum. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: MGC33147
Protein Interaction Partner: MGST1, LTC4S, ALOX5AP, ALOX5,
Protein Size: 150
Molekulargewicht 16 kDa
Gen-ID 4056
NCBI Accession NM_145867, NP_665874
UniProt Q16873
Pathways Cellular Response to Molecule of Bacterial Origin

Anwendungsinformationen

Produktdetails Antigendetails Handhabung Referenzen Bilder zurück nach oben
Applikationshinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 150 AA

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

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Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen

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Produkt verwendet in:

Tang, Sally, Lesko, Discepolo, Abadie, Ciszewski, Semrad, Guandalini, Kupfer, Jabri: "Cysteinyl leukotrienes mediate lymphokine killer activity induced by NKG2D and IL-15 in cytotoxic T cells during celiac disease." in: The Journal of experimental medicine, Vol. 212, Issue 10, pp. 1487-95, 2015

Allgemeine Veröffentlichungen

Freiberg, Tybjaerg-Hansen, Sillesen, Jensen, Nordestgaard: "Promotor polymorphisms in leukotriene C4 synthase and risk of ischemic cerebrovascular disease." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 28, Issue 5, pp. 990-6, 2008

Bilder

Produktdetails Antigendetails Anwendungsinformationen Handhabung Referenzen zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-Leukotriene C4 Synthase (LTC4S) (N-Term) antibody (ABIN2783616) WB Suggested Antibody Titration: 1 ug/ml Positive Control: HepG2