anti-Human LILRB2 Antikörper für Immunoprecipitation

Recommended LILRB2 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 2 (LILRB2) Antikörper
  • CD85D
  • ILT-4
  • ILT4
  • LIR-2
  • LIR2
  • MIR-10
  • MIR10
  • leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
  • LILRB2
Reaktivität
Human
68
4
4
Wirt
Ratte
47
15
4
2
Klonalität
Monoklonal
Konjugat
Dieser LILRB2 Antikörper ist unkonjugiert
9
5
4
4
2
2
2
2
2
2
2
2
2
1
Applikation
Flow Cytometry (FACS), Immunoprecipitation (IP)
46
26
7
4
4
3
2
2
1
1
Hersteller
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Hersteller Produkt- Nr.
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Bilder

Produktnummer ABIN2656782
Preis und Verfügbarkeit auf Anfrage.
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN2663608 FACS IP PE Rat IgG2a kappa Anmelden zum Anzeigen 42D1 5
1 ABIN2663609 FACS IP PE Rat IgG2a kappa Anmelden zum Anzeigen 42D1 5
1 ABIN5013875 ICC IHC IP WB Rabbit IgG AA 53-255 Anmelden zum Anzeigen Polyclonal

General

Antigen Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 2 (LILRB2) Antikörper
Reaktivität Human
(68), (4), (4)
Wirt Ratte
(47), (15), (4), (2)
Klonalität (Klon)
Monoklonal   ( )
Konjugat Dieser LILRB2 Antikörper ist unkonjugiert
(9), (5), (4), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1)
Applikation Flow Cytometry (FACS), Immunoprecipitation (IP)
(46), (26), (7), (4), (4), (3), (2), (2), (1), (1)
Pubmed 4 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-LILRB2 Antikörper

Target Details LILRB2 Anwendungsinformationen Handhabung Referenzen für anti-LILRB2 Antikörper (ABIN2656782) Bilder
Marke LEAF™
Reinigung The LEAF™ (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.
Sterilität 0.2 μm filtered
Endotoxin-Niveau

Endotoxin level is <0.1 EU/μg of the protein (<0.01 ng/μg of the protein) as determined by the LAL test.

Klon 42D1
Isotyp IgG2a kappa

Target Details LILRB2

Produktdetails anti-LILRB2 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-LILRB2 Antikörper (ABIN2656782) Bilder zurück nach oben
Antigen
Andere Bezeichnung CD85d (LILRB2 Antibody Abstract)
Hintergrund CD85 is a group of Ig superfamily tansmembrane glycoproteins called Ig-Like Transcripts (ILTs) or Leukocyte Immunoglobulin-like Receptors (LIRs). It is composed of both activating and inhibitory isoforms. The activating subset of ILTs is characterized by containing short cytoplasmic domains and positively charged arginine residues, while the inhibitory isoforms display long cytoplasmic tails containing ITIM motifs. CD85d is a 95kD inhibitory receptor, also known as ILT4, LIR2, or MIR10. ILT4 is expressed on the surface of monocytes/macrophages, and dendritic cells. ILT4 acts as an inhibitory receptor through recruitment of SHP-1 and SHP-2 protein tyrosine phosphatases. The ligands of ILT4 are HLA-A, -B and nonclassical MHC-I molecule HLA-G1.
Pathways Cellular Response to Molecule of Bacterial Origin

Anwendungsinformationen

Produktdetails anti-LILRB2 Antikörper Target Details LILRB2 Handhabung Referenzen für anti-LILRB2 Antikörper (ABIN2656782) Bilder zurück nach oben
Applikationshinweise Optimal working dilution should be determined by the investigator.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-LILRB2 Antikörper Target Details LILRB2 Anwendungsinformationen Referenzen für anti-LILRB2 Antikörper (ABIN2656782) Bilder zurück nach oben
Konzentration 1.0 mg/mL
Konservierungsmittel Azide free
Vorsichtsmaßnahmen This LEAF ™ solution contains no preservative, handle under aseptic conditions.
Lagerung 4 °C
Informationen zur Lagerung The antibody solution should be stored undiluted 2°C and 8°C.

Referenzen für anti-LILRB2 Antikörper (ABIN2656782)

Produktdetails anti-LILRB2 Antikörper Target Details LILRB2 Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Lichterfeld, Kavanagh, Williams, Moza, Mui, Miura, Sivamurthy, Allgaier, Pereyra, Trocha, Feeney, Gandhi, Rosenberg, Altfeld, Allen, Allen, Walker, Sundberg, Yu: "A viral CTL escape mutation leading to immunoglobulin-like transcript 4-mediated functional inhibition of myelomonocytic cells." in: The Journal of experimental medicine, Vol. 204, Issue 12, pp. 2813-24, 2007

Shiroishi, Tsumoto, Amano, Shirakihara, Colonna, Braud, Allan, Makadzange, Rowland-Jones, Willcox, Jones, van der Merwe, Kumagai, Maenaka: "Human inhibitory receptors Ig-like transcript 2 (ILT2) and ILT4 compete with CD8 for MHC class I binding and bind preferentially to HLA-G." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 15, pp. 8856-61, 2003

Allan, Colonna, Lanier, Churakova, Abrams, Ellis, McMichael, Braud: "Tetrameric complexes of human histocompatibility leukocyte antigen (HLA)-G bind to peripheral blood myelomonocytic cells." in: The Journal of experimental medicine, Vol. 189, Issue 7, pp. 1149-56, 1999

Colonna, Samaridis, Cella, Angman, Allen, OCallaghan, Dunbar, Ogg, Cerundolo, Rolink: "Human myelomonocytic cells express an inhibitory receptor for classical and nonclassical MHC class I molecules." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 160, Issue 7, pp. 3096-100, 1998

Bilder

Produktdetails anti-LILRB2 Antikörper Target Details LILRB2 Anwendungsinformationen Handhabung Referenzen für anti-LILRB2 Antikörper (ABIN2656782) zurück nach oben
Bilder des Herstellers
Flow Cytometry (FACS) image for anti-Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 2 (LILRB2) antibody (ABIN2656782) anti-Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 2 (LILRB2) antibody