Lipocalin 2 Proteine (LCN2)

Lipocalin 2 Proteine (LCN2)
Auf finden Sie aktuell 73 Lipocalin 2 (LCN2) Proteine von 19 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Lipocalin 2 Antikörper (477) und Lipocalin 2 Kits (145) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 715 Lipocalin 2 Produkte verfügbar.
24p3, AW212229, LCN2, MSFI, NGAL, Sip24
alle Proteine anzeigen Gen GeneID UniProt
LCN2 3934 P80188
LCN2 16819 P11672
LCN2 170496 P30152

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Am meisten referenzierte Lipocalin 2 Proteine

  1. Human LCN2 Protein expressed in Human Cells - ABIN2002384 : Cowland, Borregaard: Molecular characterization and pattern of tissue expression of the gene for neutrophil gelatinase-associated lipocalin from humans. in Genomics 1997 (PubMed)
    Zeige alle 5 Referenzen für 2002384

  2. Human LCN2 Protein expressed in HEK-293 - ABIN2666721 : Flo, Smith, Sato, Rodriguez, Holmes, Strong, Akira, Aderem: Lipocalin 2 mediates an innate immune response to bacterial infection by sequestrating iron. in Nature 2004 (PubMed)
    Zeige alle 5 Referenzen für 2666721

  3. Mouse (Murine) LCN2 Protein expressed in HEK-293 - ABIN2666723 : Leung, Radulovich, Zhu, Organ, Bandarchi, Pintilie, To, Panchal, Tsao: Lipocalin2 promotes invasion, tumorigenicity and gemcitabine resistance in pancreatic ductal adenocarcinoma. in PLoS ONE 2012 (PubMed)
    Zeige alle 5 Referenzen für 2666723

Weitere Proteine zu Lipocalin 2 Interaktionspartnern

Human Lipocalin 2 (LCN2) Interaktionspartner

  1. Data suggest that elevated serum LCN2 level in overweight/obese women may serve as biomarker for risk of developing metabolic syndrome (MetS); serum NGAL levels positively correlated with saturated fatty acid dietary intake; serum NGAL increased proportionally with increase in MetS risk factors. This study was conducted in the Republic of Korea.

  2. The role of LCN2 in Iron Homeostasis and Inflammation is reviewed.

  3. The results indicate that urine levels of NGAL and retinol binding protein may be independently associated with albuminuria in the diagnosis of type 2 diabetic nephropathy and may serve as novel biomarkers for the identification of type 2 diabetic nephropathy.

  4. clinical significance of serum levels of neutrophil gelatinase-associated lipocalin (sNGAL) as a biomarker for predicting in-hospital outcomes in patients with ST-elevated myocardial infarction (STEMI)

  5. Serum and urinary NGAL were higher in the critically ill group that developed acute kidney injury compared to critically ill patients without AKI.

  6. LCN-2 expression and serum levels could discriminate IGT from NGT and type 2 diabetes mellitus (T2DM)from IGT obese women and early predicting T2DM among obese women. While, LCN-2 expression level was the independent predictor of IGT in obese women. Combination of both LCN-2 expression and serum levels improved their diagnostic value in early detection of IGT and T2DM among obese women

  7. LCN2 modulated the secretion of proinflammatory cytokines in PSC of the PDAC tumor microenvironment, whereas downregulation of LCN2-specific receptor SLC22A17 (zeige SLC22A17 Proteine) blocked these effects. Our results reveal how LCN2 acts in the tumor microenvironment links obesity, inflammation, and PDAC development.

  8. Both in our animal model and in human Age-related macular degeneration (AMD (zeige AMD1 Proteine)), the AKT2 (zeige AKT2 Proteine)-NF-kappaB (zeige NFKB1 Proteine)-LCN-2 signalling axis is involved in activating the inflammatory response.

  9. Data suggget that urine neutrophil gelatinase-associated lipocalin (NGAL) may be helpful for detecting inflammation and selecting mesenchymal stem cell (MSC (zeige MSC Proteine)) transplantation timing in ischemia-reperfusion (I/R) kidney injury.

  10. effect of lipocalin 2 on thrombotic events in polycythemia vera (zeige IGF2BP3 Proteine) and essential thrombocythemia patients

Mouse (Murine) Lipocalin 2 (LCN2) Interaktionspartner

  1. Results suggest that blood brain barrier leakage occurs in white matter after subarachnoid hemorrhage (SAH (zeige ACSM3 Proteine)) and that LCN2 contributes to SAH (zeige ACSM3 Proteine)-induced blood brain barrier disruption.

  2. LCN2 overexpression in bones modifies the bone marrow microenvironment via modulation of the expression of key secreted factors and cytokines, which in turn regulate the hematopoietic stem cell niche behavior enhancing both HSC (zeige FUT1 Proteine) homing in young mice and erythrocytes production in older mice.

  3. LCN2 modulated the secretion of proinflammatory cytokines in PSC of the PDAC tumor microenvironment, whereas downregulation of LCN2-specific receptor SLC22A17 (zeige SLC22A17 Proteine) blocked these effects. Our results reveal how LCN2 acts in the tumor microenvironment links obesity, inflammation, and PDAC development.

  4. results identify lipocalin 2 as a bone-derived hormone with metabolic regulatory effects, which suppresses appetite in a MC4R (zeige MC4R Proteine)-dependent manner, and show that the control of appetite is an endocrine function of bone

  5. Lcn2 can suppress the beneficial cardiac autophagic response to ischemia and that this contributes to enhanced ischemia-induced cell death and cardiac dysfunction.

  6. Plasma levels of LCN2 measured in patients one week after ischemic stroke contribute to the prediction of clinical outcome at 90 days and reflect the systemic response to post-stroke infections

  7. may potentiate the development of psoriasis via the enhancement of Th17- and antimicrobial peptide (zeige cAMP Proteine)-mediated inflammation

  8. The acute stress protein LCN2, produced from RPE (zeige RPE Proteine) cells and the neural retina, could modulate retinal inflammation and retinal homeostasis; therefore, such families of proteins could contribute to cell survival during retinal insults.

  9. Stroma-secreted Lcn2 promotes metastasis in vitro and in vivo, thereby contributing to tumor progression.

  10. study demonstrated a pivotal and causal role of LCN2 in the development of alcoholic fatty liver disease

Pig (Porcine) Lipocalin 2 (LCN2) Interaktionspartner

  1. we demonstrated the presence of high molecular weight (HMW) complexes (130, 170, and 220 kDa) containing MMP9 (zeige MMP9 Proteine), TIMP1 (zeige TIMP1 Proteine), and NGAL (also MMP2 (zeige MMP2 Proteine) in 220 kDa complex) without proteolytic activity.

  2. porcine p25alpha (zeige Tppp Proteine) is heavily modified with a variety of modifications: phosphorylation, di- and trimethylation, citrullination and a HexNAc group.

Lipocalin 2 (LCN2) Protein Überblick

Protein Überblick

mouse homolog plays a role in IL3 withdrawal-induced apoptosis

Alternative names and synonyms associated with Lipocalin 2 (LCN2)

  • lipocalin 2 (LCN2)
  • lipocalin 2 (Lcn2)
  • lipocalin 2-like (LOC100352980)
  • 24p3 Protein
  • AW212229 Protein
  • LCN2 Protein
  • MSFI Protein
  • NGAL Protein
  • Sip24 Protein

Bezeichner auf Proteinebene für Lipocalin 2 Proteine (LCN2)

lipocalin 2 , lipocalin 2 (oncogene 24p3) , 25 kDa alpha-2-microglobulin-related subunit of MMP-9 , lipocalin-2 , migration-stimulating factor inhibitor , neutrophil gelatinase-associated lipocalin , oncogene 24p3 , p25 , siderocalin LCN2 , SV-40-induced 24P3 protein , secreted inducible protein 24 , NGAL , alpha-2-microglobulin-related protein , alpha-2U globulin-related protein

464764 Pan troglodytes
697208 Macaca mulatta
3934 Homo sapiens
16819 Mus musculus
170496 Rattus norvegicus
100153501 Sus scrofa
491320 Canis lupus familiaris
101121411 Ovis aries
526639 Bos taurus
100352980 Oryctolagus cuniculus
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