anti-IRF8 (IRF8) Antikörper

anti-Interferon Regulatory Factor 8 Antikörper (IRF8)
Auf finden Sie aktuell 103 Interferon Regulatory Factor 8 (IRF8) Antikörper von 25 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen IRF8 Proteine (12) und IRF8 Kits (7) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 130 IRF8 Produkte verfügbar.
AI893568, DKFZp469B0320, H-ICSBP, ICSBP, Icsbp1, IRF-8, IRF8, MGC140338, Myls, zgc:92252

Meistgesuchte Reaktivitäten zu anti-IRF8 (IRF8) Antikörper

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anti-Human IRF8 Antikörper:

anti-Mouse (Murine) IRF8 Antikörper:

anti-Rat (Rattus) IRF8 Antikörper:

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Am meisten referenzierte anti-IRF8 Antikörper

  1. Human Polyclonal IRF8 Primary Antibody für IHC (p), WB - ABIN303274 : Weisz, Marx, Sharf, Appella, Driggers, Ozato, Levi: Human interferon consensus sequence binding protein is a negative regulator of enhancer elements common to interferon-inducible genes. in The Journal of biological chemistry 1993 (PubMed)
    Zeige alle 3 Referenzen für 303274

  2. Human Polyclonal IRF8 Primary Antibody für FACS, WB - ABIN389336 : McGough, Yang, Huang, Georgi, Hewitt, Röcken, Tänzer, Ebert, Liu: DNA methylation represses IFN-gamma-induced and signal transducer and activator of transcription 1-mediated IFN regulatory factor 8 activation in colon carcinoma cells. in Molecular cancer research : MCR 2008 (PubMed)
    Zeige alle 3 Referenzen für 389336

  3. Human Polyclonal IRF8 Primary Antibody für FACS, WB - ABIN389337 : Tshuikina, Jernberg-Wiklund, Nilsson, Oberg: Epigenetic silencing of the interferon regulatory factor ICSBP/IRF8 in human multiple myeloma. in Experimental hematology 2008 (PubMed)
    Zeige alle 3 Referenzen für 389337

  4. Cow (Bovine) Polyclonal IRF8 Primary Antibody für IHC, WB - ABIN2792612 : Yang, Thangaraju, Greeneltch, Browning, Schoenlein, Tamura, Ozato, Ganapathy, Abrams, Liu: Repression of IFN regulatory factor 8 by DNA methylation is a molecular determinant of apoptotic resistance and metastatic phenotype in metastatic tumor cells. in Cancer research 2007 (PubMed)
    Zeige alle 2 Referenzen für 2792612

  5. Cow (Bovine) Polyclonal IRF8 Primary Antibody für WB - ABIN2777225 : Ye, Wang, Wang, Wang, Song, Hou, Zhou, Li, Ho: CD56+ T cells inhibit hepatitis C virus replication in human hepatocytes. in Hepatology (Baltimore, Md.) 2009 (PubMed)

Weitere Antikörper gegen IRF8 Interaktionspartner

Zebrafish Interferon Regulatory Factor 8 (IRF8) Interaktionspartner

  1. The vertical and paralleled Pu.1/Spi-b (zeige SPIB Antikörper) regulatory networks control the development of rostral blood island and ventral wall of dorsal aorta-borne macrophages by regulating Irf8.

  2. Study reveals that specification of all macrophages requires irf8 during an early period of zebrafish hematopoiesis but not during the adult-phase. Also, Irf8 seems to have essential roles in host defense as well.

  3. Irf8 is a critical determinant for neutrophil versus macrophage fate choice during zebrafish primitive myelopoiesis.

Human Interferon Regulatory Factor 8 (IRF8) Interaktionspartner

  1. It findings provide evidence for an additional mechanism of epigenetic IRF8 silencing during osteoclastogenesis that likely works cooperatively with DNA methylation (zeige HELLS Antikörper), further emphasizing the importance of IRF8 as a negative regulator of osteoclastogenesis.

  2. Data suggest that ubiquitin specific protease 4 (USP4 (zeige USP4 Antikörper)) interacts with interferon regulatory factor 8 (IRF8) and, by its Lys48-specific deubiquitinase/endopeptidase activity, stabilizes IRF8 protein levels in regulatory T-lymphocytes; USP4 (zeige USP4 Antikörper) and IRF8 are also expressed in helper T-lymphocytes.

  3. these data indicate that human NK cells require IRF8 for development and functional maturation and that dysregulation of this function results in severe human disease, thereby emphasizing a critical role for NK cells in human antiviral defense.

  4. down-regulation of IRF8 in the wound leads to impaired wound healing possibly through the regulation of macrophage function and apoptosis in skin wound.

  5. IRF8 may contribute to the genetic susceptibility of Behcet's disease by regulating IRF8 expression and cytokine production.

  6. IRF5 (zeige IRF5 Antikörper) and IRF8, two transcription factors with opposing functions, control TLR9 (zeige TLR9 Antikörper) signaling in human plasmacytoid dendritic cells.

  7. cytarabine-induced upregulation of the IRF8 in leukemic cells involves increased levels of ZNF224 (zeige ZNF224 Antikörper), which can counteract the repressive activity of WT1 (zeige WT1 Antikörper) on the IRF8-promoter

  8. Expression of WT1and IRF8 showed a moderate inverse correlation in acute myeloid leukemia (zeige BCL11A Antikörper) patients. WT1 (zeige WT1 Antikörper) can be used as an minimal residual disease marker, especially in patients without recurrent genetic abnormalities.

  9. Results show that IRF8 is a possible genetic variant associated with the development of HT and production of thyroid antibody

  10. The IRF8 gene variant influenced the interaction between IRF8 and NF-kappaB (zeige NFKB1 Antikörper) and thus susceptibility to systemic sclerosis.

Mouse (Murine) Interferon Regulatory Factor 8 (IRF8) Interaktionspartner

  1. Mysm1 enhanced function of the IRF2 and IRF8 promoters, suggesting that Mysm1 governs the IRFs for hematopoietic stem cell homeostasis.

  2. results show that polymorphonuclear-myeloid-derived suppressor cells arise from a newly defined granulocyte progenitors (GP) stage within the bone marrow and that IRF8 levels (and/or their downstream target genes) in those GPs (zeige NBEAL2 Antikörper) guide their expansion or contraction

  3. IRF8 differentially controls the survival.

  4. IRF8 might play a role in restraining excess lymphocyte proliferation.

  5. IRF8 controls Th1 immune response in Treg cells independent of T-bet.

  6. The authors further identified a distinct molecular signature of F4/80(hi) and CD11b (zeige ITGAM Antikörper)(hi) macrophages and found that Irf8 was vital for macrophage maturation.

  7. this study shows that myeloid-specific SIRT1 (zeige SIRT1 Antikörper) restrains pro-inflammatory processes by deacetylating IRF8

  8. IRF8 was a target of miR (zeige MLXIP Antikörper)-451a in vitro and in vivo. The data indicate the function and a target of miR (zeige MLXIP Antikörper)-451a in SLE

  9. the mechanism for the observed differential induction of the mouse Ifit1 (zeige IFIT1 Antikörper), Ifit2 (zeige IFIT2 Antikörper), and Ifit3 genes in B cells and demonstrated that the repressive effect of the transcription factor interferon regulatory factor 8 (IRF8), which is highly expressed in B cells, played an essential role in this regulation.

  10. direct the expression of a set of genes, the IRF8/IRF1 (zeige IRF1 Antikörper) regulome, that play critical roles in host inflammatory and antimicrobial defenses in mouse models of neuroinflammation and of pulmonary tuberculosis, respectively

IRF8 Antigen-Profil

Beschreibung des Gens

Interferon consensus sequence-binding protein (ICSBP) is a transcription factor of the interferon (IFN) regulatory factor (IRF) family. Proteins of this family are composed of a conserved DNA-binding domain in the N-terminal region and a divergent C-terminal region that serves as the regulatory domain. The IRF family proteins bind to the IFN-stimulated response element (ISRE) and regulate expression of genes stimulated by type I IFNs, namely IFN-alpha and IFN-beta. IRF family proteins also control expression of IFN-alpha and IFN-beta-regulated genes that are induced by viral infection.

Alternative names and synonyms associated with IRF8

  • interferon regulatory factor 8 (irf8) Antikörper
  • interferon regulatory factor 8 (IRF8) Antikörper
  • interferon regulatory factor 8 (LOC100350620) Antikörper
  • interferon regulatory factor 8 (Irf8) Antikörper
  • AI893568 Antikörper
  • DKFZp469B0320 Antikörper
  • H-ICSBP Antikörper
  • ICSBP Antikörper
  • Icsbp1 Antikörper
  • IRF-8 Antikörper
  • IRF8 Antikörper
  • MGC140338 Antikörper
  • Myls Antikörper
  • zgc:92252 Antikörper

Bezeichner auf Proteinebene für IRF8

DKEYP-77B5.1 , interferon regulatory factor 8 , interferon regulatory factor 8-like , interferon consensus sequence binding protein 1 , interferon consensus sequence-binding protein , transcription factor ICSBP , IRF-8 , interferon consensus sequence binding protein

436895 Danio rerio
454294 Pan troglodytes
489673 Canis lupus familiaris
614909 Bos taurus
693933 Macaca mulatta
100018105 Monodelphis domestica
100056218 Equus caballus
100173775 Pongo abelii
100350620 Oryctolagus cuniculus
100405221 Callithrix jacchus
100469809 Ailuropoda melanoleuca
100598495 Nomascus leucogenys
3394 Homo sapiens
446986 Xenopus laevis
15900 Mus musculus
292060 Rattus norvegicus
396385 Gallus gallus
Ausgewählte Anbieter für anti-IRF8 (IRF8) Antikörper
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