GATA1 Proteine (GATA1)

Auf www.antikoerper-online.de finden Sie aktuell 12 GATA Binding Protein 1 (Globin Transcription Factor 1) (GATA1) Proteine von 5 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen GATA1 Antikörper (245) und GATA1 Kits (31) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 301 GATA1 Produkte verfügbar.
Synonyme:
Eryf1, gata-1, Gata1, Gf-1, GF1, NF-E1, NFE1, si:dkeyp-77f7.5, XLANP, XLTDA, XLTT
alle Proteine anzeigen Gen GeneID UniProt
GATA1 2623 P15976
GATA1 14460 P17679
GATA1 25172 P43429

GATA1 Proteine (GATA1) nach Spezies

Weitere Proteine zu GATA1 Interaktionspartnern

Human GATA Binding Protein 1 (Globin Transcription Factor 1) (GATA1) Interaktionspartner

  1. expression of GATA1 effectively rescued maturation of Primary myelofibrosis megakaryocytes.

  2. GATA1 is an essential downstream target of SENP1 (zeige SENP1 Proteine) and that the differential expression and response of GATA1 and Bcl-xL (zeige BCL2L1 Proteine) are a key mechanism underlying chronic mountain sickness pathology.

  3. we herein show a long-distance regulatory region with GATA1 binding sites as being a strong enhancer for NBEAL2 expression.

  4. Single-nucleotide polymorphism in GATA1 gene is associated with non-Down syndrome transient proliferative megakaryoblastic disease.

  5. These findings indicate that erythroid specific activator GATA-1 acts at CTCF (zeige CTCF Proteine) sites around the beta-globin (zeige HBB Proteine) locus to establish tissue-specific chromatin organization.

  6. Results show that GATA1 recognizes a single GATA motif or a composite of adjacent GATA motifs and exerts its diversified bindings. These binding configurations serve as one of the critical determinants of specific transcriptional regulation.

  7. Acquired and inherited GATA1 mutations contribute to Diamond-Blackfan anemia, acute megakaryoblastic leukemia, transient myeloproliferative disorder, and a group of related congenital dyserythropoietic anemias with thrombocytopenia.

  8. Our results suggest that GATAl and miR (zeige MLXIP Proteine)-363 were involved in the regulation of hematopoiesis via the HIF-1alpha (zeige HIF1A Proteine) pathway in K562 cells under hypoxic condition.

  9. analysis of GATA1 mutations in a cohort of Malaysian children with Down syndrome-associated myeloid disorder reveals distinctive genomic events

  10. trisomy 21 perturbed hematopoietic development through the enhanced production of early hematopoietic progenitors and the upregulation of mutated GATA1, resulting in the accelerated production of aberrantly differentiated cells.

Mouse (Murine) GATA Binding Protein 1 (Globin Transcription Factor 1) (GATA1) Interaktionspartner

  1. the Gata-1 gene was a T3-directly regulated gene and that TRa1PV could impair erythropoiesis via repression of the Gata-1 gene and its regulated genes. These results provide new insights into how TRa1 (zeige HSP90B1 Proteine) mutants acted to cause erythroid abnormalities in patients with mutations of the THRA (zeige THRA Proteine) gene.

  2. Gain of function with GATA1 restores the common myeloid precursor differentiation into erythroblasts that was decreased by burn injury. There is a reciprocal relationship between myeloid-specific MafB (zeige MAFB Proteine) and erythroid-specific GATA1 in these cells. MafB (zeige MAFB Proteine) plays a role in dampening GATA1.

  3. expression of GATA1 effectively rescued maturation of Primary myelofibrosis megakaryocytes.

  4. Gata1-KO(DC) DCs have reduced polysialic acid levels on their surface, which is a known determinant for the proper migration of DCs toward CCL21 (zeige CCL21 Proteine).

  5. removal of the the Gata1 methylation-determining region -mediated silencing machinery is the molecular basis of the initial activation of the Gata1 gene and erythropoiesis.

  6. Results show that GATA1 recognizes a single GATA motif or a composite of adjacent GATA motifs and exerts its diversified bindings. These binding configurations serve as one of the critical determinants of specific transcriptional regulation.

  7. deletion of P-sel disrupted megakaryocyte/neutrophil interactions in spleen, reduced TGF-beta (zeige TGFB1 Proteine) content, and corrected the hematopoietic stem cells distribution that in Gata1(low) mice, as in primary myelofibrosis patients, is abnormally expanded in spleen.

  8. findings suggest that Gata1 & PU.1 transcription factors are only executing and reinforcing lineage choice once made. These results challenge the current prevailing model of early myeloid lineage choice

  9. GATA1 and PU.1 bind in vitro and in vivo the proximal promoter region of the RPS19 (zeige RPS19 Proteine) gene which is frequently mutated in Diamond-Blackfan Anemia.

  10. TAL1 (zeige TAL1 Proteine) and GATA1 form a precisely organized complex at a compound motif consisting of a TG 7 or 8 bp upstream of a WGATAA motif across thousands of genomic locations

GATA1 Protein Überblick

Protein Überblick

This gene encodes a protein which belongs to the GATA family of transcription factors. The protein plays an important role in erythroid development by regulating the switch of fetal hemoglobin to adult hemoglobin. Mutations in this gene have been associated with X-linked dyserythropoietic anemia and thrombocytopenia.

Alternative names and synonyms associated with GATA1

  • GATA binding protein 1 (globin transcription factor 1) (GATA1)
  • GATA binding protein 1 (Gata1)
  • amidase (gatA1)
  • aspartyl/glutamyl-tRNA amidotransferase subunit A (gatA1)
  • putative amidase (gatA1)
  • glutamyl-tRNA amidotransferase subunit A protein (gatA1)
  • GatA1 (gatA1)
  • glutamyl-tRNA amidotransferase subunit A (gatA1)
  • hematopietic transcription factor GATA-1 (gata-1)
  • GATA binding protein 1b (gata1b)
  • GATA binding protein 1 (LOC100344606)
  • Eryf1 Protein
  • gata-1 Protein
  • Gata1 Protein
  • Gf-1 Protein
  • GF1 Protein
  • NF-E1 Protein
  • NFE1 Protein
  • si:dkeyp-77f7.5 Protein
  • XLANP Protein
  • XLTDA Protein
  • XLTT Protein

Bezeichner auf Proteinebene für GATA1

GATA-binding factor 1 , NF-E1 DNA-binding protein , erythroid transcription factor , erythroid transcription factor 1 , globin transcription factor 1 , nuclear factor, erythroid 1 , transcription factor GATA1 , GATA-binding protein 1 , GATA-1 , GATA-binding protein 1 (globin transcription factor 1) , GF-1 , GATA binding protein 1 (globin transcription factor 1) , amidase , aspartyl/glutamyl-tRNA amidotransferase subunit A , putative amidase , glutamyl-tRNA amidotransferase subunit A protein , GatA1 , glutamyl-tRNA amidotransferase subunit A , hematopietic transcription factor GATA-1 , GATA 1 protein , GATA binding protein 1 , NF-E1a , eryf1 , erythroid-specific transcription factor eryf1

GENE ID SPEZIES
2623 Homo sapiens
14460 Mus musculus
25172 Rattus norvegicus
480906 Canis lupus familiaris
516066 Bos taurus
738894 Pan troglodytes
2690828 Rhodopseudomonas palustris CGA009
3890880 Rhizobium etli CFN 42
4036833 Cupriavidus metallidurans CH34
5819120 Bordetella petrii DSM 12804
6398135 Rhizobium etli CIAT 652
7366654 Agrobacterium radiobacter K84
7367275 Agrobacterium radiobacter K84
7369736 Agrobacterium radiobacter K84
7501755 Desulfobacterium autotrophicum HRM2
9452888 Bacillus cereus biovar anthracis str. CI
100125425 Oryzias latipes
100620659 Sus scrofa
564960 Danio rerio
100344606 Oryctolagus cuniculus
396450 Gallus gallus
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