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anti-Human Fibronectin Antikörper:
anti-Mouse (Murine) Fibronectin Antikörper:
anti-Rat (Rattus) Fibronectin Antikörper:
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Chicken Monoclonal Fibronectin Primary Antibody für ICC, IHC (fro) - ABIN3043242
Zhang, Chen, Qi, Wang, Xiao, Zhu: Inhibition of calcium-calmodulin-dependent kinase II suppresses cardiac fibroblast proliferation and extracellular matrix secretion. in Journal of cardiovascular pharmacology 2010
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Human Monoclonal Fibronectin Primary Antibody für FACS, IHC - ABIN969149
Ryschich, Khamidjanov, Kerkadze, Büchler, Zöller, Schmidt: Promotion of tumor cell migration by extracellular matrix proteins in human pancreatic cancer. in Pancreas 2009
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Human Monoclonal Fibronectin Primary Antibody für FACS, ELISA - ABIN969520
Huang, Zhang, Kim, Ge, Annis, Mosher, Greenspan: Fibronectin binds and enhances the activity of bone morphogenetic protein 1. in The Journal of biological chemistry 2009
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Human Monoclonal Fibronectin Primary Antibody für FACS - ABIN4898545
Purushothaman, Bandari, Liu, Mobley, Brown, Sanderson: Fibronectin on the Surface of Myeloma Cell-derived Exosomes Mediates Exosome-Cell Interactions. in The Journal of biological chemistry 2016
Injection of alpha5beta1 protein rescued the Fibronectin layer and then the myocardial precursor migration in snai1b knockdown embryos.
Fibronectin, a main component of the extracellular matrix, is induced and deposited after cardiac damage
Fibronectin deficiency resulted in a dramatic reduction of mesoderm accompanied by endodermal expansion in zebrafish embryos.
Data indicate that focal adhesion kinase (FAK) activity may be a mediator of the integrin alpha5/Fn1 interaction during zebrafish lens fiber morphogenesis.
reduction of fn1 function enables rescue of cardiac fusion in hand2 (zeige HAND2 Antikörper) mutants
Fibronectin regulates epithelial organization during myocardial migration in zebrafish.
Cancer-associated fibroblasts organize the fibronectin matrix and promote directional prostate cancer cell migration.
FN1 mutations that cause defective fibronectin secretion are found in SMD.
FN1 overexpression is an important determinant of thyroid cancer aggressiveness.
Thyroid hormone (zeige PTH Antikörper) T3 induces fibronectin and HIF-1alpha (zeige HIF1A Antikörper) synthesis via PI3K (zeige PIK3CA Antikörper)/AKT (zeige AKT1 Antikörper) signaling pathway.
Fibronectin and Hepatocyte Growth Factor (zeige HGF Antikörper) were shown to be produced by lung fibroblasts and, furthermore, to enhance malignant pleural mesothelioma cell migration and invasion
Study identifies four likely Tourette disorder risk genes with multiple de novo damaging variants in unrelated probands: WWC1 (WW and C2 domain containing 1 (zeige WWC1 Antikörper)), CELSR3 (Cadherin EGF LAG seven-pass G-type receptor 3 (zeige CELSR3 Antikörper)), NIPBL (zeige NIPBL Antikörper) (Nipped (zeige RPL38 Antikörper)-B-like), and FN1 (fibronectin 1).
fibrillar fibronectin on this polymer, but not a globular conformation obtained on control polymers, promotes synergistic presentation of integrin-binding sites and bound bone morphogenetic protein 2 (BMP-2 (zeige BMP2 Antikörper)), which enhances mesenchymal stem cell osteogenesis in vitro and drives full regeneration of a nonhealing bone defect in vivo at low GF concentrations.
Fn plays a critical role in inflammasome-activated cells by amplifying caspase-1 (zeige CASP1 Antikörper) activation and inducing inflammatory cell death.
If the expression of Capon (zeige NOS1AP Antikörper) is decreased, myeloma cells are adhered to fibronectin or bone marrow stromal cells (bone marrow mesenchymal stem cells). In addition, the sensitivity of the cell line to chemotherapeutic agents was reduced after silencing Capon (zeige NOS1AP Antikörper) in the myeloma cell line which was adhered to bone marrow mesenchymal stem cells.
C-terminal truncation of transglutaminase 2 (TG2 (zeige TGM2 Antikörper)) reduces binding to the small intestinal extracellular matrix (ECM (zeige MMRN1 Antikörper)) despite retained fibronectin (FN)-binding capacity.
Histone methyltransferase Suv39h1 (zeige SUV39H1 Antikörper) attenuates high glucose-induced fibronectin and p21(WAF1 (zeige CDKN1A Antikörper)) in mesangial cells
fibronectin has a critical role in tissue morphogenesis and the development of tissue heterogeneities
The aged stem cell niche in skeletal muscle contains reduced levels of FN, leading to detrimental consequences for the function and maintenance of muscle stem cells (MuSCs). FN is a preferred adhesion substrate for MuSCs and integrin-mediated signaling via focal adhesion kinase and the p38 MAPK (zeige MAPK14 Antikörper) pathway is strongly de-regulated in MuSCs from aged mice because of insufficient attachment to the niche.
analysis of novel functions for two fibronectin isoforms and the mediating receptors in osteoblast differentiation
scleraxis (zeige SCX Antikörper) was required for TGFbeta (zeige TGFB1 Antikörper)-induced fibronectin expression: TGFbeta (zeige TGFB1 Antikörper) lost its ability to induce fibronectin expression following scleraxis (zeige SCX Antikörper) knockdown.
The results very comprehensively demonstrate distinct signaling pathways that regulate microfilament organization, lamellipodial structures, spreading, and movement of cells plated on galectin-3 (zeige LGALS3 Antikörper) as opposed to fibronectin.
Thus, similarly to growth factor signaling, fibronectin matrix assembly during early development can be both autocrine and paracrine.
These results suggest that the Rac1 regulation of the FN arrangement is involved in retinoic acid-induced cleft palate.
Fibrillar cellular fibronectin supports platelet adhesion, activation, aggregation and procoagulant activity via the interplay of a series of receptors i.e. integrins alpha5beta1 and alphaIIbbeta3, the GPIb-V-IX complex, GPVI (zeige GP6 Antikörper) and Toll-like receptor 4 (zeige TLR4 Antikörper).
Fn1 synthesized by the neural crest mediated morphogenesis of the aortic arch artery and differentiation of neural crest cells into vascular smooth muscle cells by regulating Notch (zeige NOTCH1 Antikörper) signaling.
plasma FN assembly into bone matrix in vitro requires FXIIIA transglutaminase activity making pFN assembly an active, osteoblast-mediated process.
Fetal and adult human skin fibroblasts retain their differential proliferative response to TGF-beta (zeige TGFB1 Antikörper) when cultured in the presence of fibronectin and unpolymerized or polymerized collagen.
Putative function of fibronectin and its receptor (integrin alpha(5 (zeige ITGA5 Antikörper))beta(1)) in male and female gametes during bovine fertilization in vitro.
These results highlight a crucial role for caveolin-1 (zeige CAV1 Antikörper) in negative regulation of membrane microdomain mobility, thereby affecting endocytosis of bacteria-engaged integrins.
P. multocida-Fn interaction may play a role in the bacterium adherence to host cells, and this may be mediated by bacterial surface proteins with preferential affinity for the Hep-1 binding domain of Fn
The expression of extracellular matrix molecules fibronectin and osteopontin (zeige SPP1 Antikörper) in vitreous and retina samples in autoimmune uveitis was investigated.
The obtained results suggest that propolis modifies fibronectin metabolism in the course of wound healing process.
The relationship between hyaluronan synthesis and levels of versican (zeige Vcan Antikörper), fibronectin and several other extracellular matrix components in trabecular meshwork cells from the anterior segment of the eye was investigated.
fibronectin has a cryptic binding site for tenascin (zeige TNC Antikörper)
This gene encodes fibronectin, a glycoprotein present in a soluble dimeric form in plasma, and in a dimeric or multimeric form at the cell surface and in extracellular matrix. Fibronectin is involved in cell adhesion and migration processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis. The gene has three regions subject to alternative splicing, with the potential to produce 20 different transcript variants. However, the full-length nature of some variants has not been determined.
, gene C
, cold-insoluble globulin
, migration-stimulating factor
, cumulus cell-specific fibronectin 1 transcript
, embryo-specific fibronectin 1 transcript
, fibronectin ED-A- region
, fibronectin variable region