anti-Maus CXCL2 Antikörper für Functional Studies

Recommended CXCL2 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Chemokine (C-X-C Motif) Ligand 2 (CXCL2) Antikörper
  • GRO3
  • MIP-2alpha
  • Mip-2
  • Scyb2
  • CINC-2a
  • GRO2
  • GROb
  • MGSA-b
  • MIP-2a
  • MIP2
  • MIP2A
  • SCYB2
  • Gro2
  • MIP-2
  • Mgsa-b
  • Mip2
  • Scyb
  • GROB
  • GROX
  • CDW2
  • GID7
  • chemokine (C-X-C motif) ligand 2
  • WD repeat domain 26
  • CXCL2
  • Cxcl2
  • WDR26
Reaktivität
Maus
87
54
40
1
1
1
1
1
Wirt
Kaninchen
124
18
15
15
Klonalität
Polyklonal
Konjugat
Dieser CXCL2 Antikörper ist unkonjugiert
22
8
8
6
6
6
2
2
2
2
2
2
2
2
2
2
2
Applikation
Enzyme Immunoassay (EIA), Functional Studies (Func), Neutralization (Neut), Western Blotting (WB)
159
105
42
15
10
9
9
6
5
4
4
3
3
1
Hersteller
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Hersteller Produkt- Nr.
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Mehr erfahren

Produktnummer ABIN116268
$ 368.50
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN116267 EIA Func Neut WB Rabbit Anmelden zum Anzeigen Polyclonal 3
1 ABIN2475709 Func IHC (fro) IHC (p) ELISA WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 4
1 ABIN205701 Func ELISA WB Rabbit IgG Anmelden zum Anzeigen Polyclonal

General

Antigen Chemokine (C-X-C Motif) Ligand 2 (CXCL2) Antikörper
Reaktivität Maus
(87), (54), (40), (1), (1), (1), (1), (1)
Wirt Kaninchen
(124), (18), (15), (15)
Klonalität
Polyklonal
Konjugat Dieser CXCL2 Antikörper ist unkonjugiert
(22), (8), (8), (6), (6), (6), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Applikation Enzyme Immunoassay (EIA), Functional Studies (Func), Neutralization (Neut), Western Blotting (WB)
(159), (105), (42), (15), (10), (9), (9), (6), (5), (4), (4), (3), (3), (1)
Pubmed 3 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-CXCL2 Antikörper

Target Details CXCL2 Anwendungsinformationen Handhabung Referenzen für anti-CXCL2 Antikörper (ABIN116268) Bilder
Spezifität This antibody detects Mouse MIP-2. Other species not tested.
Reinigung Affinity Chromatography employing immobilized murine mMIP-2 matrix
Immunogen Highly pure (> 98%) E.coli derived recombinant Murine MIP-2

Target Details CXCL2

Produktdetails anti-CXCL2 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-CXCL2 Antikörper (ABIN116268) Bilder zurück nach oben
Antigen
Andere Bezeichnung CXCL2 / MIP2A (CXCL2 Antibody Abstract)
Hintergrund GRO beta is a member of the CXC, or chemokine class. It contains the ELR domain immediately preceding the first cysteine residue near the amino terminus. Other chemokines in this group include IL8, GRO alpha/beta/gamma, mouse KC, ENA78, GCP2, PBP/CTAPIII/beta TG/NAP2. These chemokines act primarily on neutrophils as chemoattractants and activators, including neutrophil degradation with release of myloperoxidase and other enzymes. GRO beta was originally identified as a heparin-binding protein secreted from a murine macrophage cell line in response to endotoxin stimulation. GRO beta is an approximately 8 kDa polypeptide of 73 amino acids. The precursor form of GRO beta consists of 100 amino acids. To generate the mature GRO beta, the precursor cleaves its amino terminal 27 amino acids. GRO beta shows 60 % amino acid homology to human GRO alpha and GRO gamma.Synonyms: C-X-C motif chemokine 2, GRO2, GROB, Gro-beta, Growth-regulated protein beta, MIP-2A, MIP2-alpha, Macrophage inflammatory protein 2-alpha, SCYB2
Gen-ID 20310
NCBI Accession NP_033166
UniProt P10889
Pathways Cellular Response to Molecule of Bacterial Origin

Anwendungsinformationen

Produktdetails anti-CXCL2 Antikörper Target Details CXCL2 Handhabung Referenzen für anti-CXCL2 Antikörper (ABIN116268) Bilder zurück nach oben
Applikationshinweise Neutralisation: To yield one-half maximal inhibition [ND50] of the biological activity of mMIP-2 (15.00 ng/mL), a concentration of 0.52-0.90 μg/mL of this antibody is required. ELISA: Indirect: Using 100 μL/well antibody solution, a concentration of 0.5 - 2.0 μg/mL isrequired. In conjunction with compatible secondary reagents, it allows the detection of atleast 0.2 - 0.4 ng/well of recombinant mMIP-2. Sandwich: Using 100 μL/well antibody solution, a concentration of 0.5 - 2.0 μg/mL isrequired. In conjunction with Biotinylated Anti-Murine MIP-2 (PP1082B) as a detectionantibody, it allows the detection of at least 0.2 - 0.4 ng/well of recombinant mMIP-2. Western Blot: 0.1-0.2 μg/mL. Used in conjunction with compatible secondary reagents thedetection limit for recombinant mMIP-2 is 1.5-3.0 ng/lane, under either reducing ornon-reducing conditions.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-CXCL2 Antikörper Target Details CXCL2 Anwendungsinformationen Referenzen für anti-CXCL2 Antikörper (ABIN116268) Bilder zurück nach oben
Rekonstitution Centrifuge vial prior to opening. Restore in sterile water to a concentration of 0.1-1.0 mg/mL.
Buffer PBS, pH 7.2
Handhabung Avoid repeated freezing and thawing.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Prior to reconstitution store at 2-8 °C. Following reconstitution store (in aliquots) at -20 °C.

Referenzen für anti-CXCL2 Antikörper (ABIN116268)

Produktdetails anti-CXCL2 Antikörper Target Details CXCL2 Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Gonzalez-Rey, Chorny, Robledo, Delgado: "Cortistatin, a new antiinflammatory peptide with therapeutic effect on lethal endotoxemia." in: The Journal of experimental medicine, Vol. 203, Issue 3, pp. 563-71, 2006

Michalec, Choudhury, Postlethwait, Wild, Alam, Lett-Brown, Sur: "CCL7 and CXCL10 orchestrate oxidative stress-induced neutrophilic lung inflammation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 168, Issue 2, pp. 846-52, 2002

Lentsch, Kato, Davis, Wang, Chao, Edwards: "STAT4 and STAT6 regulate systemic inflammation and protect against lethal endotoxemia." in: The Journal of clinical investigation, Vol. 108, Issue 10, pp. 1475-82, 2001