anti-Human CCR5 Antikörper für Flow Cytometry

Recommended CCR5 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
C-C Chemokine Receptor Type 5 (CCR5) Antikörper
  • CC-CKR-5
  • CCCKR5
  • CCR-5
  • CD195
  • CKR-5
  • CKR5
  • CMKBR5
  • IDDM22
  • Ckr5
  • Cmkbr5
  • CCR1-L
  • GPCR
  • CCR5
  • AM4-7
  • CCR5-L
  • chemokine (C-C motif) receptor 5 (gene/pseudogene)
  • chemokine (C-C motif) receptor 5
  • chemokine (C-C motif) receptor 2
  • C-C chemokine receptor type 5-like
  • CCR5
  • Ccr5
  • CCR2
  • LOC100399144
Reaktivität
Human
475
81
66
14
14
3
2
1
1
1
1
1
Wirt
Ratte
229
182
71
15
14
Klonalität
Monoklonal
Konjugat
Dieser CCR5 Antikörper ist unkonjugiert
43
27
20
19
16
14
13
13
9
9
9
6
6
5
5
5
5
4
4
4
4
4
4
3
3
2
2
2
2
2
2
1
1
1
1
1
1
Applikation
Flow Cytometry (FACS)
303
209
141
66
64
57
57
33
29
18
14
12
8
8
6
5
4
4
3
2
2
2
2
2
1
1
1
Hersteller
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Bilder

Produktnummer ABIN1449163
396,00 €
Zzgl. Versandkosten 20,00 € und MWSt
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
14.327658 ABIN2853594 FACS FITC Rat IgG1 Anmelden zum Anzeigen T227 5
14.327658 ABIN4895436 FACS PE Mouse IgG2b AA 1-352 Anmelden zum Anzeigen 45531 6
14.327658 ABIN4895435 FACS PE Mouse IgG2b AA 1-352 Anmelden zum Anzeigen 45531 6
14.327658 ABIN4895434 FACS Fluorescein Mouse IgG2b AA 1-352 Anmelden zum Anzeigen 45531 4
14.327658 ABIN4895433 FACS Fluorescein Mouse IgG2b AA 1-352 Anmelden zum Anzeigen 45531 4
14.327658 ABIN4898221 FACS Fluorescein Mouse IgG1 Anmelden zum Anzeigen CTC5 2
14.327658 ABIN4898219 FACS Allophycocyanin Mouse IgG1 Anmelden zum Anzeigen CTC5 5
14.327658 ABIN4898220 FACS Allophycocyanin Mouse IgG1 Anmelden zum Anzeigen CTC5 5
14.327658 ABIN4898223 FACS PE Mouse IgG1 Anmelden zum Anzeigen CTC5 6
14.327658 ABIN4898222 FACS Fluorescein Mouse IgG1 Anmelden zum Anzeigen CTC5 2
14.327658 ABIN4898224 FACS PE Mouse IgG1 Anmelden zum Anzeigen CTC5 6
14.327658 ABIN151963 Func ICC FACS IF in vitro ELISA WB Rabbit Anmelden zum Anzeigen Polyclonal 2
14.327658 ABIN614398 EIA FACS IHC (p) IP WB Mouse IgG1 Anmelden zum Anzeigen T21-8
14.327658 ABIN2478977 FACS Rat IgG2a Anmelden zum Anzeigen HEK-1-85a 4
14.327658 ABIN1381740 cELISA FACS ELISA Mouse IgG1 Anmelden zum Anzeigen NP-6G4 5
14.327658 ABIN1177340 FACS Mouse IgG2a, kappa Anmelden zum Anzeigen 2D7-CCR5 7
14.327658 ABIN2658039 FACS Alexa Fluor 700 Rat IgG2a kappa Anmelden zum Anzeigen HEK-1-85a 10
14.327658 ABIN2656995 FACS APC Mouse IgG1 kappa phosphorylated Anmelden zum Anzeigen E11-19 6
14.327658 ABIN2663965 FACS PE Mouse IgG1 kappa phosphorylated Anmelden zum Anzeigen E11-19 7
14.327658 ABIN2657665 FACS Alexa Fluor 647 Rat IgG2a kappa Anmelden zum Anzeigen HEK-1-85a 10

General

Antigen C-C Chemokine Receptor Type 5 (CCR5) Antikörper
Reaktivität Human
(475), (81), (66), (14), (14), (3), (2), (1), (1), (1), (1), (1)
Wirt Ratte
(229), (182), (71), (15), (14)
Klonalität (Klon)
Monoklonal   ( )
Konjugat Dieser CCR5 Antikörper ist unkonjugiert
(43), (27), (20), (19), (16), (14), (13), (13), (9), (9), (9), (6), (6), (5), (5), (5), (5), (4), (4), (4), (4), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Applikation Flow Cytometry (FACS)
(303), (209), (141), (66), (64), (57), (57), (33), (29), (18), (14), (12), (8), (8), (6), (5), (4), (4), (3), (2), (2), (2), (2), (2), (1), (1), (1)
Pubmed 5 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-CCR5 Antikörper

Target Details CCR5 Anwendungsinformationen Handhabung Referenzen für anti-CCR5 Antikörper (ABIN1449163) Bilder
Spezifität This antibody reacts with CD195 antigen.
Kreuzreaktivität (Details) Species reactivity (tested):Human
Reinigung Ammonium sulfate precipitation followed by gel filtration through Superdex 200 in PBS
Immunogen Syngeneic human CD195 transfectants
Klon T227
Isotyp IgG1

Target Details CCR5

Produktdetails anti-CCR5 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-CCR5 Antikörper (ABIN1449163) Bilder zurück nach oben
Antigen
Andere Bezeichnung CD195 / CCR5 (CCR5 Antibody Abstract)
Hintergrund CD195/CCR5, is a seven transmembrane receptor that is a member of the ß-chemokine receptor family. CCR5 is expressed by T cells and macrophages, and is one of the two major co-receptors for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with resistance to HIV infection, and early infection with HIV-1 is dominated by CCR5-tropic viruses. The ligands of the CCR5 receptor include MCP-2, MIP-1a, MIP-1ß, and RANTES. CCR5 is phosphorylated at specific sites by protein kinase C and GPCR kinase, and data show that two distinct forms of CCR5 protein, 62 and 42 kDa, are present in lymphocytic cells. CCR5 expression was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation.Synonyms: C-C CKR-5, C-C chemokine receptor type 5, CC-CKR-5, CCR-5, CHEMR13, CMKBR5, HIV-1 fusion coreceptor
Gen-ID 1234
NCBI Accession NP_000570
UniProt P51681
Forschungsgebiet CD Antigens, Surface Receptors of Immune Cells, Chemokines, Receptors
Pathways Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Regulation of Cell Size

Anwendungsinformationen

Produktdetails anti-CCR5 Antikörper Target Details CCR5 Handhabung Referenzen für anti-CCR5 Antikörper (ABIN1449163) Bilder zurück nach oben
Applikationshinweise Optimal working dilution should be determined by the investigator.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-CCR5 Antikörper Target Details CCR5 Anwendungsinformationen Referenzen für anti-CCR5 Antikörper (ABIN1449163) Bilder zurück nach oben
Konzentration 1.0 mg/mL
Buffer PBS containing 50 % glycerol, pH 7.2. No preservative is contained.
Konservierungsmittel Without preservative
Handhabung Avoid repeated freezing and thawing.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Referenzen für anti-CCR5 Antikörper (ABIN1449163)

Produktdetails anti-CCR5 Antikörper Target Details CCR5 Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Nimura, Zhang, Okuma, Tanaka, Sunakawa, Yamamoto, Tanaka: "Cross-linking cell surface chemokine receptors leads to isolation, activation, and differentiation of monocytes into potent dendritic cells." in: Experimental biology and medicine (Maywood, N.J.), Vol. 231, Issue 4, pp. 431-43, 2006

Ichiyama, Yokoyama-Kumakura, Tanaka, Tanaka, Hirose, Bannai, Edamatsu, Yanaka, Niitani, Miyano-Kurosaki, Takaku, Koyanagi, Yamamoto: "A duodenally absorbable CXC chemokine receptor 4 antagonist, KRH-1636, exhibits a potent and selective anti-HIV-1 activity." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 7, pp. 4185-90, 2003

Yoshida, Tanaka, Murakami, Takahashi, Koyanagi, Nakamura, Ito, Yamamoto, Tanaka: "Induction of protective immune responses against R5 human immunodeficiency virus type 1 (HIV-1) infection in hu-PBL-SCID mice by intrasplenic immunization with HIV-1-pulsed dendritic cells: possible involvement of a novel factor of human CD4(+) T-cell ori" in: Journal of virology, Vol. 77, Issue 16, pp. 8719-28, 2003

Tanaka, Yoshida, Murakami, Baba, Lichtenfeld, Omori, Kimura, Tsurutani, Fujii, Wang, Peiper, Yamamoto, Tanaka: "Unique monoclonal antibody recognizing the third extracellular loop of CXCR4 induces lymphocyte agglutination and enhances human immunodeficiency virus type 1-mediated syncytium formation and productive infection." in: Journal of virology, Vol. 75, Issue 23, pp. 11534-43, 2001

Shioda, Nakayama, Tanaka, Xin, Liu, Kawana-Tachikawa, Kato, Sakai, Nagai, Iwamoto: "Naturally occurring deletional mutation in the C-terminal cytoplasmic tail of CCR5 affects surface trafficking of CCR5." in: Journal of virology, Vol. 75, Issue 7, pp. 3462-8, 2001

Bilder

Produktdetails anti-CCR5 Antikörper Target Details CCR5 Anwendungsinformationen Handhabung Referenzen für anti-CCR5 Antikörper (ABIN1449163) zurück nach oben
Bilder des Herstellers
Flow Cytometry (FACS) image for anti-C-C Chemokine Receptor Type 5 (CCR5) antibody (ABIN1449163) anti-C-C Chemokine Receptor Type 5 (CCR5) antibody