anti-Human CCR5 Antikörper für Cytometry by Time of Flight

Recommended CCR5 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
C-C Chemokine Receptor Type 5 (CCR5) Antikörper
  • CC-CKR-5
  • CCCKR5
  • CCR-5
  • CD195
  • CKR-5
  • CKR5
  • CMKBR5
  • IDDM22
  • Ckr5
  • Cmkbr5
  • CCR1-L
  • GPCR
  • CCR5
  • AM4-7
  • CCR5-L
  • chemokine (C-C motif) receptor 5 (gene/pseudogene)
  • chemokine (C-C motif) receptor 5
  • chemokine (C-C motif) receptor 2
  • C-C chemokine receptor type 5-like
  • CCR5
  • Ccr5
  • CCR2
  • LOC100399144
Epitop
AA 1-352
51
34
19
15
14
12
11
10
10
9
8
8
7
6
4
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human
475
81
66
14
14
3
2
1
1
1
1
1
Wirt
Maus
228
182
72
15
14
Klonalität
Monoklonal
Konjugat
Dieser CCR5 Antikörper ist unkonjugiert
43
27
20
19
16
14
13
13
9
9
9
6
6
5
5
5
5
4
4
4
4
4
4
3
3
2
2
2
2
2
2
1
1
1
1
1
1
Applikation
Cytometry by Time of Flight (CyTOF), Flow Cytometry (FACS), Immunocytochemistry (ICC), Neutralization (Neut)
303
209
141
66
64
57
56
33
29
18
14
12
8
7
6
5
4
4
3
2
2
2
2
1
1
1
1
Hersteller
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Bilder

Produktnummer ABIN4899075
263,00 €
Zzgl. Versandkosten 20,00 € und MWSt
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN4899076 CyTOF FACS Mouse IgG2b AA 1-352 Anmelden zum Anzeigen 45529 5
1 ABIN4899074 CyTOF FACS Mouse IgG2b AA 1-352 Anmelden zum Anzeigen 45502 5
1 ABIN4900690 CyTOF FACS WB Mouse IgG1 Anmelden zum Anzeigen CTC5 3
1 ABIN2659152 CyTOF FACS IHC IP PE-Cy7 Mouse IgG2b kappa Anmelden zum Anzeigen J418F1 1
1 ABIN4289124 CyTOF FACS IF IHC (fro) Mouse IgG2a kappa N-Term Anmelden zum Anzeigen 12D1
1 ABIN4289125 CyTOF FACS IF IHC (fro) Mouse IgG2a kappa N-Term Anmelden zum Anzeigen 12D1
1 ABIN2659153 CyTOF FACS IHC IP PE-Cy7 Mouse IgG2b kappa Anmelden zum Anzeigen J418F1 1

General

Antigen C-C Chemokine Receptor Type 5 (CCR5) Antikörper
Epitop AA 1-352
(51), (34), (19), (15), (14), (12), (11), (10), (10), (9), (8), (8), (7), (6), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Human
(475), (81), (66), (14), (14), (3), (2), (1), (1), (1), (1), (1)
Wirt Maus
(228), (182), (72), (15), (14)
Klonalität (Klon)
Monoklonal   ( )
Konjugat Dieser CCR5 Antikörper ist unkonjugiert
(43), (27), (20), (19), (16), (14), (13), (13), (9), (9), (9), (6), (6), (5), (5), (5), (5), (4), (4), (4), (4), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Applikation Cytometry by Time of Flight (CyTOF), Flow Cytometry (FACS), Immunocytochemistry (ICC), Neutralization (Neut)
(303), (209), (141), (66), (64), (57), (56), (33), (29), (18), (14), (12), (8), (7), (6), (5), (4), (4), (3), (2), (2), (2), (2), (1), (1), (1), (1)
Pubmed 17 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-CCR5 Antikörper

Target Details CCR5 Anwendungsinformationen Handhabung Referenzen für anti-CCR5 Antikörper (ABIN4899075) Bilder
Spezifität Detects human CCR5.
Reinigung Protein A or G purified from ascites
Sterilität 0.2 μm filtered
Endotoxin-Niveau <0.10 EU per 1 μg of the antibody by the LAL method.
Immunogen NS0 mouse myeloma cell line transfected with human CCR5, Met1-Leu352, Accession # P51681
Klon 45531
Isotyp IgG2b

Target Details CCR5

Produktdetails anti-CCR5 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-CCR5 Antikörper (ABIN4899075) Bilder zurück nach oben
Antigen
Andere Bezeichnung CCR5 (CCR5 Antibody Abstract)
Hintergrund Alternative Names: C-C CKR-5, C-C motif chemokine receptor 5 A159A, CCCKR5, CC-CKR-5FLJ78003, CCR5, CCR-5, CD195, CD195 antigen, chemokine (C-C motif) receptor 5, chemokine receptor CCR5, chemr13, CKR5, CKR-5, HIV-1 fusion coreceptor, IDDM22CMKBR5C-C chemokine receptor type 5
Gen-ID 1234
UniProt P51681
Forschungsgebiet Atherosclerosis, Chemokines, Signaling, CD Antigens, Receptors, Alzheimer's Disease, Innate Immunity, Cardiovascular
Pathways Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Regulation of Cell Size

Anwendungsinformationen

Produktdetails anti-CCR5 Antikörper Target Details CCR5 Handhabung Referenzen für anti-CCR5 Antikörper (ABIN4899075) Bilder zurück nach oben
Applikationshinweise Flow Cytometry 2.5 μg/10^6 cells
Neutralization 5-20 μg/mL
Immunocytochemistry 8-25 μg/mL
CyTOF-ready
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-CCR5 Antikörper Target Details CCR5 Anwendungsinformationen Referenzen für anti-CCR5 Antikörper (ABIN4899075) Bilder zurück nach oben
Rekonstitution Reconstitute at 0.5 mg/mL in sterile PBS.
Buffer Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Konservierungsmittel Without preservative
Lagerung 4 °C,-20 °C,-80 °C
Informationen zur Lagerung Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt,-20°C to -70°C as supplied. 1 month,2°C to 8°C under sterile conditions after reconstitution. 6 months,-20°C to -70°C under sterile conditions after reconstitution.
Haltbarkeit 12 months

Referenzen für anti-CCR5 Antikörper (ABIN4899075)

Produktdetails anti-CCR5 Antikörper Target Details CCR5 Anwendungsinformationen Handhabung Bilder zurück nach oben
Produkt verwendet in:

Ward, Li, Hepburn, Weston, Curbishley, Reynolds, Hejmadi, Bicknell, Eksteen, Ismail, Rot, Adams: "The effects of CCR5 inhibition on regulatory T-cell recruitment to colorectal cancer." in: British journal of cancer, Vol. 112, Issue 2, pp. 319-28, 2015 Von den Autoren verwendete Methode: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Probematerial (Species): Human).

Flegler, Cianci, Hope: "CCR5 conformations are dynamic and modulated by localization, trafficking and G protein association." in: PLoS ONE, Vol. 9, Issue 2, pp. e89056, 2014 Von den Autoren verwendete Methode: Immunohistochemistry (IHC) (Probematerial (Species): Human).

Alonzo, Kozhaya, Rawlings, Reyes-Robles, DuMont, Myszka, Landau, Unutmaz, Torres: "CCR5 is a receptor for Staphylococcus aureus leukotoxin ED." in: Nature, Vol. 493, Issue 7430, pp. 51-5, 2013 Von den Autoren verwendete Methode: Biochemical Assay (BCA) (Probematerial (Species): Human).

Jung, Che, Kim, Kim, Kim, Williams, Kim: "Tumor-stromal crosstalk in invasion of oral squamous cell carcinoma: a pivotal role of CCL7." in: International journal of cancer, Vol. 127, Issue 2, pp. 332-44, 2010 Von den Autoren verwendete Methode: Neutralization (Neut) (Probematerial (Species): Human).

Franciszkiewicz, Le Floch, Jalil, Vigant, Robert, Vergnon, Mackiewicz, Benihoud, Validire, Chouaib, Combadière, Mami-Chouaib: "Intratumoral induction of CD103 triggers tumor-specific CTL function and CCR5-dependent T-cell retention." in: Cancer research, Vol. 69, Issue 15, pp. 6249-55, 2009 Von den Autoren verwendete Methode: Flow Cytometry (FACS) (Probematerial (Species): Human).

Hartl, Krauss-Etschmann, Koller, Hordijk, Kuijpers, Hoffmann, Hector, Eber, Marcos, Bittmann, Eickelberg, Griese, Roos: "Infiltrated neutrophils acquire novel chemokine receptor expression and chemokine responsiveness in chronic inflammatory lung diseases." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 181, Issue 11, pp. 8053-67, 2008 Von den Autoren verwendete Methode: Flow Cytometry (FACS) (Probematerial (Species): Human).

Aldinucci, Lorenzon, Cattaruzza, Pinto, Gloghini, Carbone, Colombatti: "Expression of CCR5 receptors on Reed-Sternberg cells and Hodgkin lymphoma cell lines: involvement of CCL5/Rantes in tumor cell growth and microenvironmental interactions." in: International journal of cancer, Vol. 122, Issue 4, pp. 769-76, 2007 Von den Autoren verwendete Methode: Flow Cytometry (FACS) (Probematerial (Species): Human).

Kang, Lim, Andrisani, Broxmeyer, Kim: "Vitamin A metabolites induce gut-homing FoxP3+ regulatory T cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 179, Issue 6, pp. 3724-33, 2007 Von den Autoren verwendete Methode: Flow Cytometry (FACS) (Probematerial (Species): Human).

Bolovan-Fritts, Spector: "Endothelial damage from cytomegalovirus-specific host immune response can be prevented by targeted disruption of fractalkine-CX3CR1 interaction." in: Blood, Vol. 111, Issue 1, pp. 175-82, 2007 Von den Autoren verwendete Methode: Neutralization (Neut) (Probematerial (Species): Human).

Abonyo, Lebby, Tonry, Ahmad, Heiman: "Modulation of eotaxin-3 (CCL26) in alveolar type II epithelial cells." in: Cytokine, Vol. 36, Issue 5-6, pp. 237-44, 2007 Von den Autoren verwendete Methode: Neutralization (Neut) (Probematerial (Species): Human).

Gounni Abdelilah, Wellemans, Agouli, Guenounou, Hamid, Beck, Lamkhioued: "Increased expression of Th2-associated chemokines in bullous pemphigoid disease. Role of eosinophils in the production and release of these chemokines." in: Clinical immunology (Orlando, Fla.), Vol. 120, Issue 2, pp. 220-31, 2006 Von den Autoren verwendete Methode: Neutralization (Neut) (Probematerial (Species): Human).

Lepej, Rode, Jeren, Vince, Remenar, Barsić: "Increased expression of CXCR3 and CCR5 on memory CD4+ T-cells migrating into the cerebrospinal fluid of patients with neuroborreliosis: the role of CXCL10 and CXCL11." in: Journal of neuroimmunology, Vol. 163, Issue 1-2, pp. 128-34, 2005 Von den Autoren verwendete Methode: Flow Cytometry (FACS) (Probematerial (Species): Human).

Ottonello, Montecucco, Bertolotto, Arduino, Mancini, Corcione, Pistoia, Dallegri: "CCL3 (MIP-1alpha) induces in vitro migration of GM-CSF-primed human neutrophils via CCR5-dependent activation of ERK 1/2." in: Cellular signalling, Vol. 17, Issue 3, pp. 355-63, 2004 Von den Autoren verwendete Methode: Flow Cytometry (FACS) (Probematerial (Species): Human).

Lim, Hillsamer, Kim: "Regulatory T cells can migrate to follicles upon T cell activation and suppress GC-Th cells and GC-Th cell-driven B cell responses." in: The Journal of clinical investigation, Vol. 114, Issue 11, pp. 1640-9, 2004 Von den Autoren verwendete Methode: Immunocytochemistry (ICC) (Probematerial (Species): Human).

Giunti, Borsellino, Benelli, Marchese, Capello, Valle, Pedemonte, Noonan, Albini, Bernardi, Mancardi, Battistini, Uccelli: "Phenotypic and functional analysis of T cells homing into the CSF of subjects with inflammatory diseases of the CNS." in: Journal of leukocyte biology, Vol. 73, Issue 5, pp. 584-90, 2003 Von den Autoren verwendete Methode: Neutralization (Neut) (Probematerial (Species): Human).

Howard, Dong, Yang, Raben, Nagaraju, Rosen, Casciola-Rosen, Härtlein, Kron, Yang, Yiadom, Dwivedi, Plotz, Oppenheim: "Histidyl-tRNA synthetase and asparaginyl-tRNA synthetase, autoantigens in myositis, activate chemokine receptors on T lymphocytes and immature dendritic cells." in: The Journal of experimental medicine, Vol. 196, Issue 6, pp. 781-91, 2002 Von den Autoren verwendete Methode: Neutralization (Neut) (Probematerial (Species): Human).

Lee, Sharron, Blanpain, Doranz, Vakili, Setoh, Berg, Liu, Guy, Durell, Parmentier, Chang, Price, Tsang, Doms: "Epitope mapping of CCR5 reveals multiple conformational states and distinct but overlapping structures involved in chemokine and coreceptor function." in: The Journal of biological chemistry, Vol. 274, Issue 14, pp. 9617-26, 1999 Von den Autoren verwendete Methode: Flow Cytometry (FACS) (Probematerial (Species): Human).

Bilder

Produktdetails anti-CCR5 Antikörper Target Details CCR5 Anwendungsinformationen Handhabung Referenzen für anti-CCR5 Antikörper (ABIN4899075) zurück nach oben
Bilder des Herstellers
Immunocytochemistry (ICC) image for anti-C-C Chemokine Receptor Type 5 (CCR5) (AA 1-352) antibody (ABIN4899075) CCR5 in Human Dendritic Cells. CCR5 was detected in immersion fixed human dendritic c...
Neutralization (Neut) image for anti-C-C Chemokine Receptor Type 5 (CCR5) (AA 1-352) antibody (ABIN4899075) Chemotaxis Induced by CCL3/MIP-1 alpha and Neutraliza-tion by Human CCR5 Antibody. Re...
Immunocytochemistry (ICC) image for anti-C-C Chemokine Receptor Type 5 (CCR5) (AA 1-352) antibody (ABIN4899075) CCR5 in Human Dendritic Cells. CCR5 was detected in immersion fixed human dendritic c...