anti-Kaninchen Arginase, Liver Antikörper für Immunohistochemistry

Recommended Arginase, Liver Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Arginase, Liver (ARG1) Antikörper
  • SI:zC146F4.4 (novel protein with NUDIX domain)
  • si:ch211-146f4.3
  • argi1
  • AI
  • AI256583
  • Arg-1
  • PGIF
  • arginase 1
  • arginase, liver
  • arginase-1
  • Arginase-1
  • L-arginase
  • arg1
  • PGTG_16455
  • argi1
  • ARG1
  • Arg1
Epitop
N-Term
70
55
18
18
9
7
7
7
5
5
3
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
Reaktivität
Rind (Kuh), Hund, Ziege, Meerschweinchen, Pferd, Human, Maus, Schwein, Kaninchen, Ratte (Rattus), Yeast
209
80
74
23
15
13
7
4
3
2
2
2
1
Wirt
Kaninchen
158
52
48
13
4
Klonalität
Polyklonal
Konjugat
Unkonjugiert
13
13
12
10
8
7
3
3
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Applikation
Immunohistochemistry (IHC), Western Blotting (WB)
203
120
49
46
43
22
22
13
5
4
3
2
2
2
2
1
1
1
1
1
Optionen
Hersteller
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Bilder

Produktnummer ABIN2782309
$ 289.00
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
8.866798 ABIN2773866 IHC WB Rabbit N-Term Anmelden zum Anzeigen Polyclonal 2
8.866798 ABIN2782310 IHC WB Rabbit C-Term Anmelden zum Anzeigen Polyclonal 1
1 ABIN2203868 IC IHC ELISA WB Guinea Pig IgG Anmelden zum Anzeigen Polyclonal

General

Antigen Arginase, Liver (ARG1) Antikörper
Epitop N-Term
(70), (55), (18), (18), (9), (7), (7), (7), (5), (5), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Rind (Kuh), Hund, Ziege, Meerschweinchen, Pferd, Human, Maus, Schwein, Kaninchen, Ratte (Rattus), Yeast
(209), (80), (74), (23), (15), (13), (7), (4), (3), (2), (2), (2), (1)
Wirt Kaninchen
(158), (52), (48), (13), (4)
Klonalität
Polyklonal
Konjugat Unkonjugiert
(13), (13), (12), (10), (8), (7), (3), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Immunohistochemistry (IHC), Western Blotting (WB)
(203), (120), (49), (46), (43), (22), (22), (13), (5), (4), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Pubmed 1 Publikation vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails

Antigendetails Anwendungsinformationen Handhabung Referenzen Bilder
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN973376.
Sequenz SAKSRTIGII GAPFSKGQPR GGVEEGPTVL RKAGLLEKLK EQECDVKDYG
Kreuzreaktivität Rind (Kuh), Human, Maus, Schwein, Kaninchen, Ratte (Rattus)
Homologie Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Yeast: 85%
Produktmerkmale This is a rabbit polyclonal antibody against ARG1. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human ARG1

Antigendetails

Produktdetails Anwendungsinformationen Handhabung Referenzen Bilder zurück nach oben
Antigen
Andere Bezeichnung Arginase-1 (ARG1 Antibody Abstract)
Hintergrund Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia.Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform encoded by this gene, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: -
Protein Interaction Partner: RPA3, RPA2, RPA1, SUZ12, EZH2, BMI1, ALDH4A1, ESR1, RAD21, UBC, UCHL5, ATG101, USP53, FLOT1, NOS1, ARG2,
Protein Size: 322
Molekulargewicht 35 kDa
Gen-ID 383
NCBI Accession NM_000045, NP_000036
UniProt P05089
Pathways Cellular Response to Molecule of Bacterial Origin

Anwendungsinformationen

Produktdetails Antigendetails Handhabung Referenzen Bilder zurück nach oben
Applikationshinweise WB Suggested Anti-ARG1 Antibody Titration: 0.2-1 µg/mL
ELISA Titer: 1:1562500
Positive Control: Human Liver.
Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 322 AA

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails Antigendetails Anwendungsinformationen Referenzen Bilder zurück nach oben
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen

Produktdetails Antigendetails Anwendungsinformationen Handhabung Bilder zurück nach oben
Produkt verwendet in:

Kitowska, Zakrzewicz, Königshoff, Chrobak, Grimminger, Seeger, Bulau, Eickelberg: "Functional role and species-specific contribution of arginases in pulmonary fibrosis." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 294, Issue 1, pp. L34-45, 2008

Bilder

Produktdetails Antigendetails Anwendungsinformationen Handhabung Referenzen zurück nach oben
Bilder des Herstellers
Immunohistochemistry (IHC) image for anti-Arginase, Liver (ARG1) (N-Term) antibody (ABIN2782309) anti-Arginase, Liver (ARG1) (N-Term) antibody
Immunohistochemistry (IHC) image for anti-Arginase, Liver (ARG1) (N-Term) antibody (ABIN2782309) anti-Arginase, Liver (ARG1) (N-Term) antibody (Image 2)