Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C) Proteine (PVRL1)

Bezeichnung:
Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C) Proteine (PVRL1)
Auf www.antikoerper-online.de finden Sie aktuell 21 Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C) (PVRL1) Proteine von 9 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C) Antikörper (91) und Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C) Kits (17) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 142 Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C) Produkte verfügbar.
Synonyme:
AI835281, AW549174, CD111, cd112, CLPED1, ED4, HIgR, hveb, HveC, nectin-1, nectin-2, OFC7, PRR, PRR1, prr2, PVRL1, PVRR, PVRR1, pvrr2, SK-12
alle Proteine anzeigen Gen GeneID UniProt
PVRL1 58235 Q9JKF6
PVRL1 192183  
PVRL1 5818 Q15223

Weitere Synonyme anzeigen

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Am meisten referenzierte Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C) Proteine

  1. Human PVRL1 Protein expressed in Human Cells - ABIN2004431 : Lopez, Cocchi, Avitabile, Leclerc, Adelaide, Campadelli-Fiume, Dubreuil: Novel, soluble isoform of the herpes simplex virus (HSV) receptor nectin1 (or PRR1-HIgR-HveC) modulates positively and negatively susceptibility to HSV infection. in Journal of virology 2001 (PubMed)
    Zeige alle 7 Referenzen für 2004431

  2. Rat (Rattus) PVRL1 Protein expressed in Human Cells - ABIN2009369 : Reymond, Fabre, Lecocq, Adelaïde, Dubreuil, Lopez: Nectin4/PRR4, a new afadin-associated member of the nectin family that trans-interacts with nectin1/PRR1 through V domain interaction. in The Journal of biological chemistry 2001 (PubMed)
    Zeige alle 7 Referenzen für 2009369

  3. Human PVRL1 Protein expressed in HEK-293 Cells - ABIN2181679 : Lopez, Eberlé, Mattei, Gabert, Birg, Bardin, Maroc, Dubreuil: Complementary DNA characterization and chromosomal localization of a human gene related to the poliovirus receptor-encoding gene. in Gene 1995 (PubMed)
    Zeige alle 2 Referenzen für 2181679

Weitere Proteine zu Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C) Interaktionspartnern

Mouse (Murine) Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C) (PVRL1) Interaktionspartner

  1. Nectin-1 promotes chlamydial infection in the female genital tract but does not appear to contribute to rectal infection in male mice.

  2. nectin-1 regulates the neuronal activities in the CA3 (zeige CA3 Proteine) region of the hippocampus.

  3. Novel type of cell adhesion apparatus is mediated by Nectin-1 and Nectin-4 (zeige PVRL4 Proteine). It's implicated in prolactin receptor (zeige PRLR Proteine) signaling for mammary gland development.

  4. These results indicate that the nectin-1 spots regulate the branching of mitral cell dendrites in the deep sub-lamina of the EPL and suggest that the nectin-1 spots are required for odor information processing in the olfactory bulb.

  5. Results indicate that the nectin-1 spots constitute a novel adhesion apparatus that tethers mitral cell dendrites in a dendritic meshwork structure of the developing mouse olfactory bulb

  6. results demonstrate a role for both nectin-1 and HVEM (zeige TNFRSF14 Proteine) as receptors and suggest a further receptor which appears much less efficient.

  7. Pvrl1 is a bona fide target gene of the transcription factor p63 (zeige CKAP4 Proteine), whereas Pvrl4 (zeige PVRL4 Proteine) regulation is linked to epidermal differentiation and is under Irf6 (zeige IRF6 Proteine)

  8. In summary, herpes simplex virus 1 entry into epidermis was shown to strongly depend on the presence of nectin-1, but the restricted presence of HVEM (zeige TNFRSF14 Proteine) can potentially replace nectin-1 as a receptor.

  9. This study demonstrated that nectin1- and nectin3 (zeige PVRL3 Proteine)-mediated interactions between Cajal-Retzius cells cells and migrating neurons are critical for radial migration

  10. PRR1 nectin-1 plays a role in the formation of intimal thickening after carotid artery ligation.

Human Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C) (PVRL1) Interaktionspartner

  1. In a transgenic mouse line with high expression of nectin-1Ig, significant protection from the infection with 30 and 300 MLD50 was observed .

  2. nectin-1 is expressed in human hair follicles and there is a p63 (zeige RPE65 Proteine)-responsive element in the NECTIN1 promoter

  3. The viral entry receptor Nectin-1 is also internalized during HSV-1 infection in a Cbl (zeige CBL Proteine)-dependent mechanism, and that increases the opportunity of the virus to spread to uninfected cells.

  4. HSV gD is able to disrupt intercellular homophilic trans-interaction of nectin-1 and induce a rapid redistribution of nectin-1 from cell junctions.

  5. PVRL1 variants make a contribution to non syndromic Cleft Lip with/without Cleft palate in Turkish patients.

  6. PDZD11 forms a complex with nectin-1 and nectin-3 (zeige PVRL3 Proteine), and its PDZ domain interacts directly with the PDZ-binding motif of nectin-1.

  7. mutations in exons 2 and 5 of PVRL1, and T334A, A391T, G1183A in the alpha-spliced transcript, and G1082T in the beta-spliced transcript do not participate in the development of non-syndromic cleft of the lip and/or palate in patients from Guangdong.

  8. data suggests that E-cadherin regulates assembly of nectin junctions through alpha-catenin-induced remodeling of the actin cytoskeleton around the cadherin clusters.

  9. The results showed that the interface between the BV gD and nectin-1 molecule is not geometrically complementary.

  10. These data provided solid structural and functional evidence that herpes simplex virus 1 and herpes simplex virus 2 gD proteins recognize nectin-1 via the same binding mode.

Pig (Porcine) Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C) (PVRL1) Interaktionspartner

  1. Contribution of the second and third Ig-like domains of nectin-1 was analysed by generating transgenic mice expressing the entire ectodomain of nectin-1 fused to the porcine Fc portion.

  2. Results demonstrate that a soluble form of the first domain of porcine nectin-1 is able to exert a significant antiviral effect against pseudorabies virus infection.

Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C) (PVRL1) Protein Überblick

Protein Überblick

This gene encodes an adhesion protein that plays a role in the organization of adherens junctions and tight junctions in epithelial and endothelial cells. The protein is a calcium(2+)-independent cell-cell adhesion molecule that belongs to the immunoglobulin superfamily and has 3 extracellular immunoglobulin-like loops, a single transmembrane domain (in some isoforms), and a cytoplasmic region. This protein acts as a receptor for glycoprotein D (gD) of herpes simplex viruses 1 and 2 (HSV-1, HSV-2), and pseudorabies virus (PRV) and mediates viral entry into epithelial and neuronal cells. Mutations in this gene cause cleft lip and palate/ectodermal dysplasia 1 syndrome (CLPED1) as well as non-syndromic cleft lip with or without cleft palate (CL/P). Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini.

Alternative names and synonyms associated with Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C) (PVRL1)

  • poliovirus receptor-related 1 (herpesvirus entry mediator C) (PVRL1)
  • poliovirus receptor-related 1 (herpesvirus entry mediator C) (Pvrl1)
  • poliovirus receptor-related protein 1-like (LOC100857875)
  • poliovirus receptor-related 2 (herpesvirus entry mediator B) (pvrl2)
  • poliovirus receptor-related protein 1 (pvrl1)
  • Poliovirus receptor-related protein 1 (pvrl1)
  • poliovirus receptor-related 1 (herpesvirus entry mediator C) (pvrl1)
  • poliovirus receptor-related 1 (LOC100341399)
  • poliovirus receptor-related 1 (Pvrl1)
  • AI835281 Protein
  • AW549174 Protein
  • CD111 Protein
  • cd112 Protein
  • CLPED1 Protein
  • ED4 Protein
  • HIgR Protein
  • hveb Protein
  • HveC Protein
  • nectin-1 Protein
  • nectin-2 Protein
  • OFC7 Protein
  • PRR Protein
  • PRR1 Protein
  • prr2 Protein
  • PVRL1 Protein
  • PVRR Protein
  • PVRR1 Protein
  • pvrr2 Protein
  • SK-12 Protein

Bezeichner auf Proteinebene für PVRL1

poliovirus receptor-related 1 (herpesvirus entry mediator C; nectin) , herpesvirus entry mediator C , nectin , poliovirus receptor related protein , poliovirus receptor-related protein 1 , nectin 2 , poliovirus receptor-related 1 (herpesvirus entry mediator C) , Poliovirus receptor-related protein 1 , poliovirus receptor-related 1 , herpes virus entry mediator C , nectin-1 alpha , nectin-1 delta , nectin) , poliovirus receptor-related 1 (herpesvirus entry mediator C , ectodermal dysplasia 4 (Margarita Island type) , herpesvirus Ig-like receptor , nectin 1 , poliovirus receptor-like 1 , nectin-1

GENE ID SPEZIES
489363 Canis lupus familiaris
533492 Bos taurus
100724766 Cavia porcellus
100857875 Gallus gallus
448156 Xenopus (Silurana) tropicalis
710072 Macaca mulatta
100074768 Ornithorhynchus anatinus
100145553 Xenopus (Silurana) tropicalis
100286721 Salmo salar
100564991 Anolis carolinensis
100341399 Oryctolagus cuniculus
58235 Mus musculus
192183 Rattus norvegicus
5818 Homo sapiens
397247 Sus scrofa
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