Occludin Proteine (OCLN)

Bezeichnung:
Occludin Proteine (OCLN)
Auf www.antikoerper-online.de finden Sie aktuell 9 Occludin (OCLN) Proteine von 5 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Occludin Antikörper (119) und Occludin Kits (46) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 185 Occludin Produkte verfügbar.
Synonyme:
AI503564, BLCPMG, Ocl, ocln, oclnb, tpmt, wu:fd23h10, wu:fi13c01, zgc:56359, zgc:113992
alle Proteine anzeigen Gen GeneID UniProt
OCLN 4950  
OCLN 18260 Q61146
Ratte OCLN OCLN 83497 Q6P6T5

Weitere Synonyme anzeigen

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Weitere Proteine zu Occludin Interaktionspartnern

Human Occludin (OCLN) Interaktionspartner

  1. Intracellular zinc has an essential role in the maintenance of the intestinal epithelial tight junction barrier through regulation of occludin proteolysis and claudin-3 (zeige CLDN3 Proteine) transcription.

  2. Data suggest that long noncoding RNA PlncRNA1 and microRNA miR (zeige MLXIP Proteine)-34c bound together to regulate the expressions of MAZ (zeige MAZ Proteine), ZO-1 (zeige TJP1 Proteine) and occludin.

  3. Study provides evidence that occludin contributes to the regulation of size-reductive proliferation and epithelial cell maturation in a phosphorylation-dependent manner.

  4. Report shows that silencing MARCH3 (zeige MARCH3 Proteine) protects the endothelial barrier and upregulates OCLN in MARCH3 (zeige MARCH3 Proteine)-depleted cells. MARCH3 (zeige MARCH3 Proteine) silencing results in the strengthening of cell-cell contacts and inactivates FoxO1 (zeige FOXO1 Proteine).

  5. STAT3 activation downregulates the ZO-1 and occludin levels and increases the endothelial permeability through the induction of VEGF production in retinal endothelial cells.

  6. Downregulation of OCLN is associated with clear cell renal cell carcinoma (zeige MOK Proteine).

  7. These data suggest that the Rho/ROCK signaling pathway is involved in HIV-1 Tat (zeige TAT Proteine)-mediated changes in occludin, RAGE (zeige AGER Proteine), and LRP1 (zeige LRP1 Proteine) in human cerebral microvascular endothelial cells cells.

  8. OCLN is essential for HCV infection of human hepatic cells.

  9. OCLN and ZO1 (zeige TJP1 Proteine) levels appear to be early prognostic markers in patients suffering from sepsis.

  10. autotypic tight junctions molecular composition, like claudin-1 (zeige CLDN7 Proteine) and occludin expression could influence the demyelinating process by altering the permeability of the blood-nerve barrier.

Cow (Bovine) Occludin (OCLN) Interaktionspartner

  1. ADMA has potent adverse effects on cell proliferation, intracellular ROS (zeige ROS1 Proteine) generation, cell permeability, levels of ICAM-1 (zeige ICAM1 Proteine), and the tight-junction protein occludin

  2. the presence of occludin at the membrane is dependent in part on calcium-sensitive signaling cascades

  3. cyclic strain modulates both the expression and phosphorylation state of occludin and ZO-1 (zeige TJP1 Proteine) in vascular endothelial cells, with putative consequences for endothelial tight junction assembly and barrier integrity

  4. These data demonstrate a novel mechanism of VEGF (zeige VEGFA Proteine)-induced occludin phosphorylation and ubiquitination that contributes to TJ trafficking and subsequent vascular permeability.

Mouse (Murine) Occludin (OCLN) Interaktionspartner

  1. Intracellular zinc has an essential role in the maintenance of the intestinal epithelial tight junction barrier through regulation of occludin proteolysis and claudin-3 (zeige CLDN3 Proteine) transcription.

  2. miR-429 could down-regulate the expression of Ocln by targeting the Ocln 3'-UTR, which impaired intestinal barrier function in diabetes mellitus mice.

  3. STAT3 activation downregulates the ZO-1 and occludin levels and increases the endothelial permeability through the induction of VEGF production in retinal endothelial cells.

  4. Tricellulin (zeige MARVELD2 Proteine) is a specific redox sensor and sealing element at 3-cell contacts and may compensate as a redox mediator for occludin loss at 2-cell contacts in vivo and in vitro.

  5. These findings provide evidence for occludin playing a role in the invasion of Toxoplasma gondii in small intestinal epithelial cells.

  6. occludin deficiency increases susceptibility to ethanol-induced colonic mucosal barrier dysfunction and liver damage in mice.

  7. PHD3 (zeige EGLN3 Proteine) protects intestinal epithelial barrier function and reveal a hydroxylase-independent function of PHD3 (zeige EGLN3 Proteine) in stabilizing occludin

  8. Zonula occludens-1 (zeige TJP1 Proteine), occludin and E-cadherin (zeige CDH1 Proteine) expression and organization in salivary glands

  9. Our study demonstrates spatiotemporal alterations in occludin mRNA- and protein-expression, indicating that Cx43 (zeige GJA1 Proteine) might act as a regulator for blood-testis-barrier

  10. Occludin and Claudin-1 (zeige CLDN1 Proteine) expressions in the large intestine are under the circadian control, which is associated with temporal regulation of colonic permeability and also susceptibility to colitis.

Pig (Porcine) Occludin (OCLN) Interaktionspartner

  1. ZO-1 (zeige TJP1 Proteine) and occludin are expressed in oocytes and preimplantation embryos, and that ZO-1alpha+ is transcribed by zygotic gene activation and translated from early blastocysts with prominent increase of occludin at the blastocyst stage.

Rabbit Occludin (OCLN) Interaktionspartner

Occludin (OCLN) Protein Überblick

Protein Überblick

This gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1.5 Mb downstream on the q arm of chromosome 5.

Alternative names and synonyms associated with Occludin (OCLN)

  • occludin (OCLN)
  • occludin (ocln)
  • occludin (Ocln)
  • occludin (ocln-b)
  • occludin a (oclna)
  • AI503564 Protein
  • BLCPMG Protein
  • Ocl Protein
  • ocln Protein
  • oclnb Protein
  • tpmt Protein
  • wu:fd23h10 Protein
  • wu:fi13c01 Protein
  • zgc:56359 Protein
  • zgc:113992 Protein

Bezeichner auf Proteinebene für Occludin Proteine (OCLN)

occludin , tight junction protein occludin TM4 minus , thiopurine methyltransferase , occludin-like , tight junction protein occludin , tight-junction protein , occludin b

GENE ID SPEZIES
100073306 Equus caballus
4950 Homo sapiens
548702 Xenopus (Silurana) tropicalis
700504 Macaca mulatta
741925 Pan troglodytes
100031291 Monodelphis domestica
100077299 Ornithorhynchus anatinus
100386012 Callithrix jacchus
100462976 Oncorhynchus mykiss
100583496 Nomascus leucogenys
100506658 Homo sapiens
403844 Canis lupus familiaris
512405 Bos taurus
18260 Mus musculus
83497 Rattus norvegicus
398133 Xenopus laevis
397236 Sus scrofa
100527952 Cavia porcellus
100338492 Oryctolagus cuniculus
396026 Gallus gallus
443201 Ovis aries
100174190 Pongo abelii
405757 Danio rerio
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