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Mouse (Murine) Occludin ELISA Kit für Sandwich ELISA - ABIN425437
Summa, Voigt, Forsyth, Shaikh, Cavanaugh, Tang, Vitaterna, Song, Turek, Keshavarzian: Disruption of the Circadian Clock in Mice Increases Intestinal Permeability and Promotes Alcohol-Induced Hepatic Pathology and Inflammation. in PLoS ONE 2013
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Human Occludin ELISA Kit für Sandwich ELISA - ABIN417945
Xu, Feng, Xie, Zhang, Wu, Xu: HIV-1 Tat protein increases the permeability of brain endothelial cells by both inhibiting occludin expression and cleaving occludin via matrix metalloproteinase-9. in Brain research 2012
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Viral infectivity was significantly reduced by miR (zeige MLXIP ELISA Kits)-200c but enhanced by miR (zeige MLXIP ELISA Kits)-122.
The mechanism of transition from nondifferentiated to differentiated states in HepaRG cells was studed by proteomics. Two key factors (MMP-14 (zeige MMP14 ELISA Kits) and OCLN) were validated by qRT-PCR and Western blot.
Intracellular zinc has an essential role in the maintenance of the intestinal epithelial tight junction barrier through regulation of occludin proteolysis and claudin-3 (zeige CLDN3 ELISA Kits) transcription.
Data suggest that long noncoding RNA PlncRNA1 and microRNA miR (zeige MLXIP ELISA Kits)-34c bound together to regulate the expressions of MAZ, ZO-1 (zeige TJP1 ELISA Kits) and occludin.
Study provides evidence that occludin contributes to the regulation of size-reductive proliferation and epithelial cell maturation in a phosphorylation-dependent manner.
Report shows that silencing MARCH3 (zeige MARCH3 ELISA Kits) protects the endothelial barrier and upregulates OCLN in MARCH3 (zeige MARCH3 ELISA Kits)-depleted cells. MARCH3 (zeige MARCH3 ELISA Kits) silencing results in the strengthening of cell-cell contacts and inactivates FoxO1 (zeige FOXO1 ELISA Kits).
STAT3 activation downregulates the ZO-1 and occludin levels and increases the endothelial permeability through the induction of VEGF production in retinal endothelial cells.
Downregulation of OCLN is associated with clear cell renal cell carcinoma.
These data suggest that the Rho/ROCK signaling pathway is involved in HIV-1 Tat (zeige TAT ELISA Kits)-mediated changes in occludin, RAGE (zeige AGER ELISA Kits), and LRP1 (zeige LRP1 ELISA Kits) in human cerebral microvascular endothelial cells cells.
OCLN is essential for HCV infection of human hepatic cells.
ADMA has potent adverse effects on cell proliferation, intracellular ROS (zeige ROS1 ELISA Kits) generation, cell permeability, levels of ICAM-1 (zeige ICAM1 ELISA Kits), and the tight-junction protein occludin
the presence of occludin at the membrane is dependent in part on calcium-sensitive signaling cascades
cyclic strain modulates both the expression and phosphorylation state of occludin and ZO-1 (zeige TJP1 ELISA Kits) in vascular endothelial cells, with putative consequences for endothelial tight junction assembly and barrier integrity
These data demonstrate a novel mechanism of VEGF (zeige VEGFA ELISA Kits)-induced occludin phosphorylation and ubiquitination that contributes to TJ trafficking and subsequent vascular permeability.
The zinc sensing receptor, ZnR/GPR39 (zeige GPR39 ELISA Kits), triggers intracellular Ca(2 (zeige CA2 ELISA Kits)+) signalling in colonocytes thereby inducing occludin expression. Moreover, ZnR/GPR39 (zeige GPR39 ELISA Kits) is essential for epithelial barrier recovery in the dextran sodium sulfate (DSS (zeige PMP22 ELISA Kits)) ulcerative colitis model.
Occludin expression by epidermal gammadelta T cells upon activation in response to epidermal stress allows them to move, which could be important for augmentation of immune responses via collaboration with other cells.
miR (zeige MLXIP ELISA Kits)-429 could down-regulate the expression of Ocln by targeting the Ocln 3'-UTR (zeige UTS2R ELISA Kits), which impaired intestinal barrier function in diabetes mellitus mice.
Tricellulin (zeige MARVELD2 ELISA Kits) is a specific redox sensor and sealing element at 3-cell contacts and may compensate as a redox mediator for occludin loss at 2-cell contacts in vivo and in vitro.
These findings provide evidence for occludin playing a role in the invasion of Toxoplasma gondii in small intestinal epithelial cells.
occludin deficiency increases susceptibility to ethanol-induced colonic mucosal barrier dysfunction and liver damage in mice.
PHD3 (zeige EGLN3 ELISA Kits) protects intestinal epithelial barrier function and reveal a hydroxylase-independent function of PHD3 (zeige EGLN3 ELISA Kits) in stabilizing occludin
Zonula occludens-1 (zeige TJP1 ELISA Kits), occludin and E-cadherin (zeige CDH1 ELISA Kits) expression and organization in salivary glands
ZO-1 (zeige TJP1 ELISA Kits) and occludin are expressed in oocytes and preimplantation embryos, and that ZO-1alpha+ is transcribed by zygotic gene activation and translated from early blastocysts with prominent increase of occludin at the blastocyst stage.
This gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1.5 Mb downstream on the q arm of chromosome 5.
, tight-junction protein
, thiopurine methyltransferase
, tight junction protein occludin