anti-Numb Homolog (Drosophila)-Like (NUMBL) Antikörper

Bezeichnung:
anti-Numb Homolog (Drosophila)-Like Antikörper (NUMBL)
Auf www.antikoerper-online.de finden Sie aktuell 67 Numb Homolog (Drosophila)-Like (NUMBL) Antikörper von 15 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Numb Homolog (Drosophila)-Like Proteine (4) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 74 Numb Homolog (Drosophila)-Like Produkte verfügbar.
Synonyme:
CAG3A, CTG3a, NBL, numb, NUMB-R, NUMBLIKE, NUMBR, TNRC23
Alle Antikörper anzeigen Gen GeneID UniProt
NUMBL 9253 Q9Y6R0
NUMBL 292732  
NUMBL 18223 O08919

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Am meisten referenzierte anti-Numb Homolog (Drosophila)-Like Antikörper

  1. Human Polyclonal NUMBL Primary Antibody für IHC (p), WB - ABIN658002 : Zhou, Ma, Shi, Huo: NUMBL interacts with TRAF6 and promotes the degradation of TRAF6. in Biochemical and biophysical research communications 2010 (PubMed)
    Zeige alle 2 Referenzen für 658002

Weitere Antikörper gegen Numb Homolog (Drosophila)-Like Interaktionspartner

Xenopus laevis Numb Homolog (Drosophila)-Like (NUMBL) Interaktionspartner

  1. Results show an essential role of NumbL during Xenopus primary neurogenesis and provide evidence for a Notch (zeige NOTCH1 Antikörper)-independent function of NumbL.

Human Numb Homolog (Drosophila)-Like (NUMBL) Interaktionspartner

  1. investigations revealed that NUMB (zeige NUMB Antikörper) and NUMBL interacted with small GTPase (zeige RACGAP1 Antikörper) Rab7 (zeige RAB7B Antikörper) to transition ERBB2 (zeige ERBB2 Antikörper) from early to late endosome for degradation.

  2. These findings highlight the importance of Numb (zeige NUMB Antikörper) and Numbl in the control of myoepithelial cell fate determination, epithelial identity, and lactogenesis

  3. Numb/Numbl control VEGF receptor (zeige FLT1 Antikörper) endocytosis, signaling, and recycling in endothelial cells, which promotes the angiogenic growth of blood vessels.

  4. Numbl might be involved in the inhibition of growth, proliferation, and invasion of 95-D lung cancer cells.

  5. Numbl-Klf4 (zeige KLF4 Antikörper) signaling is critical to maintain multiple nodes of metastatic progression, including persistence of cancer-initiating cells.

  6. data suggest that Numbl regulates glioma cell migration and invasion by abrogating TRAF5 (zeige TRAF5 Antikörper)-induced activation of NF-KappaB (zeige NFKB1 Antikörper)

  7. NUMBL interacts with TRAF6 (zeige TRAF6 Antikörper) and promotes the degradation of TRAF6 (zeige TRAF6 Antikörper) in vivo, leading to the inhibition of NF-kappaB (zeige NFKB1 Antikörper) signaling pathway.

  8. Both gene sequence alterations and amplifications of LNX1 (zeige LNX1 Antikörper) and Numbl are present in a subset of human gliomas.

Mouse (Murine) Numb Homolog (Drosophila)-Like (NUMBL) Interaktionspartner

  1. investigations revealed that NUMB (zeige NUMB Antikörper) and NUMBL interacted with small GTPase (zeige RACGAP1 Antikörper) Rab7 (zeige RAB7A Antikörper) to transition ERBB2 (zeige ERBB2 Antikörper) from early to late endosome for degradation.

  2. These findings highlight the importance of Numb (zeige NUMB Antikörper) and Numbl in the control of myoepithelial cell fate determination, epithelial identity, and lactogenesis

  3. findings demonstrate that Nb and Nbl are intrinsic factors crucial for the renewal of CPCs in the PA2 and that the PA2 serves as a microenvironment for their expansion

  4. Numb/Numbl control VEGF receptor (zeige FLT1 Antikörper) endocytosis, signaling, and recycling in endothelial cells, which promotes the angiogenic growth of blood vessels.

  5. By ablating Numb (zeige NUMB Antikörper) and Numbl in different cardiac populations followed by lineage tracing, we determined that Numb (zeige NUMB Antikörper) and Numbl in the second heart field are required for outflow tract (OFT) and atrioventricular septation and OFT alignment.

  6. Concomitant but not separate ablation of Numb (zeige NUMB Antikörper) and Numblike in the developing heart leads to increased Notch2 (zeige NOTCH2 Antikörper) activity along with hypertrabeculation, reduced compaction, and ventricular septum defects.

  7. Numbl is a physiologically relevant target of miR (zeige MLXIP Antikörper)-34a in neural progenitor cells, allowing for enhanced Notch (zeige NOTCH1 Antikörper) signaling and inhibition of neuronal differentiation.

  8. the data demonstrate that Numb (zeige NUMB Antikörper) and Numblike have evolved to acquire at least partially distinct functions.

  9. mouse numb (zeige NUMB Antikörper) and numblike play redundant but critical roles in maintaining neural progenitor cells during embryogenesis, by allowing their progenies to choose progenitor over neuronal fates

  10. Numblike plays an essential role in the control of cortical morphogenesis, a process requiring precise regulation of neural progenitor cell proliferation, differentiation, and apoptosis.

Numb Homolog (Drosophila)-Like (NUMBL) Antigen-Profil

Beschreibung des Gens

Plays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. Not required for the proliferation of neural progenitor cells before the onset of embryonic neurogenesis. Also required postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity. Negative regulator of NF-kappa-B signaling pathway. The inhibition of NF- kappa-B activation is mediated at least in part, by preventing MAP3K7IP2 to interact with polyubiquitin chains of TRAF6 and RIPK1 and by stimulating the 'Lys-48'-linked polyubiquitination and degradation of TRAF6 in cortical neurons.

Alternative names and synonyms associated with Numb Homolog (Drosophila)-Like (NUMBL)

  • numb homolog (Drosophila)-like (NUMBL) Antikörper
  • numb homolog-like (numbl) Antikörper
  • numb homolog (Drosophila)-like (Numbl) Antikörper
  • numb-like (Numbl) Antikörper
  • CAG3A Antikörper
  • CTG3a Antikörper
  • NBL Antikörper
  • numb Antikörper
  • NUMB-R Antikörper
  • NUMBLIKE Antikörper
  • NUMBR Antikörper
  • TNRC23 Antikörper

Bezeichner auf Proteinebene für NUMBL

numb homolog-like , numb-like protein , numb-related protein

GENE ID SPEZIES
100068203 Equus caballus
100462918 Xenopus laevis
9253 Homo sapiens
292732 Rattus norvegicus
612491 Canis lupus familiaris
510973 Bos taurus
18223 Mus musculus
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