Use your antibodies-online credentials, if available.
Keine Produkte auf Ihrer Vergleichsliste.
Ihr Warenkorb ist leer.
Alle Spezies anzeigen
Weitere Synonyme anzeigen
Select your species
Tumor necrosis factor-alpha (zeige TNF ELISA Kits) increases claudin-1, 4, and 7 expression in renal tubular cells, altering permeability and transepithelial electrical resistance.
Cyclosporine A/sirolimus alter claudin-1 expression in renal proximal tubular cells via ERK1/2 (zeige MAPK1/3 ELISA Kits) signaling pathway to alter barrier function.
These findings indicate a previously unrecognized mechanism that miR (zeige MLXIP ELISA Kits)-142-5p, targeting CLDN1, plays an important role in Hashimoto's thyroiditis pathogenesis.
Here, the authors identified an interaction between claudin-1 (zeige CLDN7 ELISA Kits) and Sec24C, a cargo-sorting component of the coat protein (zeige GOLPH3 ELISA Kits) complex II (COPII) vesicular transport system.
Aberrant expression of the tight junction molecules claudin-1 (zeige CLDN7 ELISA Kits) and zonula occludens-1 (zeige TJP1 ELISA Kits) mediates cell growth and invasion in oral squamous cell carcinoma cells.
Increased expression of intestinal epithelial claudin-1 (zeige CLDN7 ELISA Kits) with downregulation of claudin-3 (zeige CLDN3 ELISA Kits) has been observed in intestinal inflammatory disorders.
Studies indicate claudin 1 (CLDN-1) as a target for improving epidermal drug absorption and preventing HCV infection and of claudin 4 (CLDN-4 (zeige CLDN4 ELISA Kits)) as a target for anticancer therapeutics.
Data show that the charge of Lys65 in claudin 1 (Cldn1) and Glu158 in claudin 3 (Cldn3 (zeige CLDN3 ELISA Kits)), and of Gln57 in claudin 5 (Cldn5 (zeige CLDN5 ELISA Kits)) are necessary for tight junction (TJ) strand formation.
Studies indicate that claudin-1 (zeige CLDN7 ELISA Kits) accumulate in early endosomes in both epithelial and endothelial cells.
These results revealed that CLDN1 contributed to cancer stem cell features of hepatocellular carcinoma, which was altered by TMPRSS4 (zeige TMPRSS4 ELISA Kits) expression via ERK1/2 (zeige MAPK1/3 ELISA Kits) signaling pathway, providing promising targets for novel specific therapies.
Data suggest that epithelial-mesenchymal transition (EMT (zeige ITK ELISA Kits)) is regulated by ZMYND8 (receptor for activated protein kinase C (zeige GNB2L1 ELISA Kits)) which selectively activates gene promoters of CLDN1 (claudin 1) and CDH1 (E-cadherin (zeige CDH1 ELISA Kits)) in breast cancer cells; thus, the presence of ZMYND8 could be implicated in maintaining epithelial phenotype of cells; ZMYND8 regulates invasion/migration of breast cancer cells.
The data suggested that miR (zeige MLXIP ELISA Kits)-29a may regulate tumor growth and migration by targeting CLDN1.
Taken together, these results demonstrate that BTZ (zeige CASC3 ELISA Kits)-induced claudin 1 expression may be a valuable therapeutic approach for AD.
Results suggest that TLR4 (zeige TLR4 ELISA Kits)-dependent claudin-1 internalization and secondary anion secretion contribute to irinotecan-induced diarrhea.
Data show that the spatiotemporal expression of claudin-1 is dysregulated in homeobox (zeige PRRX1 ELISA Kits) (Msx) genes Msx1d/d/Msx2d/d uteri.
Cldn-1 is a positive regulator of osteoblast proliferation and differentiation.
We further demonstrate that KRT76 interacts with CLDN1 and propose that this interaction is necessary to correctly position CLDN1 in tight junctions.
MIR29 targets and reduces expression of CLDN1 and NKRF (zeige NKRF ELISA Kits) to increase intestinal permeability in inflammatory bowel disease.
Occludin (zeige OCLN ELISA Kits) and Claudin-1 expressions in the large intestine are under the circadian control, which is associated with temporal regulation of colonic permeability and also susceptibility to colitis.
regulates intestinal epithelial homeostasis via regulation of Notch (zeige NOTCH1 ELISA Kits)-signalling
Downregulation of Sirt1 (zeige SIRT1 ELISA Kits) and upregulation of the tight junction protein Claudin-1 by SIRT1 (zeige SIRT1 ELISA Kits)-mediated epigenetic regulation in podocytes contributed to albuminuria.
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome.
, claudin 19
, claudin 1
, senescence-associated epithelial membrane protein 1
, tight junction protein