anti-ANK2 (ANK2) Antikörper

Auf www.antikoerper-online.de finden Sie aktuell 97 Ankyrin 2, Neuronal (ANK2) Antikörper von 10 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen ANK2 Kits (21) und und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 119 ANK2 Produkte verfügbar.
Synonyme:
AI835472, ANK-2, ANK2, Ank3, ANKB, AW491075, brank-2, CHANK2, LQT4, zgc:101738
Alle Antikörper anzeigen Gen GeneID UniProt
ANK2 109676 Q8C8R3
ANK2 287 Q01484
ANK2 362036  

Meistgesuchte Reaktivitäten zu anti-ANK2 (ANK2) Antikörper

anti-Mouse (Murine) ANK2 Antikörper:

anti-Human ANK2 Antikörper:

anti-Rat (Rattus) ANK2 Antikörper:

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Weitere Antikörper gegen ANK2 Interaktionspartner

Mouse (Murine) Ankyrin 2, Neuronal (ANK2) Interaktionspartner

  1. The identification and characterization of two functionally distinct ankyrin-B isoforms in heart provide compelling evidence that alternative splicing of the ANK2 gene regulates the fidelity of ankyrin-B interactions with proteins

  2. Taken together, these observations reveal that AnkB (zeige ANKH Antikörper) is required for Prx (zeige PRX Antikörper) membrane anchoring and for maintenance of lens fiber cell hexagonal geometry, membrane skeleton organization, and biomechanics.

  3. that ankyrin-B deficiency results in a metabolic syndrome that combines primary pancreatic beta cell insufficiency with peripheral insulin (zeige INS Antikörper) resistance

  4. Functional relationships between PIK3C3 (zeige PIK3C3 Antikörper), dynactin (zeige DCTN1 Antikörper), and AnkB (zeige ANKH Antikörper) promote axonal transport of organelles and are required for normal axon length.

  5. These findings identify an interaction between ankyrin-B and both Cav2.1 (zeige CACNA1A Antikörper) and Cav2.2 (zeige CACNA1B Antikörper) at the amino acid level that is necessary for proper Cav2.1 (zeige CACNA1A Antikörper) and Cav2.2 (zeige CACNA1B Antikörper) targeting in vivo.

  6. Ankyrin-B protein (zeige LEPREL2 Antikörper) in heart failure: identification of a new component of metazoan cardioprotection.

  7. AnkB (zeige ANKH Antikörper) reduction alters cardiac Na and Ca transport and enhances the coupled RyR (zeige RYR1 Antikörper) openings, resulting in more frequent Ca sparks and waves although the total SR Ca leak is unaffected.

  8. Ankyrin-B then interacts with dynactin-4 (zeige DCTN5 Antikörper) and dystrophin (zeige DMD Antikörper), whereas dynactin-4 (zeige DCTN5 Antikörper) collaborates with dystrophin (zeige DMD Antikörper) in coordinating costamere-aligned microtubules

  9. Ankyrin-B regulates Kir6.2 (zeige KCNJ11 Antikörper) membrane expression and function in heart.

  10. Findings highlight the importance of the functional anatomy of the entire atrial distributed pacemaker complex and clearly demonstrate the role of AnkB (zeige ANKH Antikörper) in cardiac automaticity.

Human Ankyrin 2, Neuronal (ANK2) Interaktionspartner

  1. VariousANK2mutations are associated with a wide range of phenotypes, including aLQTS, especially with ventricular fibrillation, representing "ankyrin-B" syndrome.

  2. Rare Variants in ANK2 Associated With Various Inherited Arrhythmia Syndromes.

  3. The identification and characterization of two functionally distinct ankyrin-B isoforms in heart provide compelling evidence that alternative splicing of the ANK2 gene regulates the fidelity of ankyrin-B interactions with proteins

  4. the structures of ANK (zeige ANK1 Antikörper) repeats in complex with an inhibitory segment from the C-terminal regulatory domain and with a sodium channel Nav1.2 (zeige SCN2A Antikörper) peptide, are reported.

  5. Gankyrin (zeige PSMD10 Antikörper) plays an essential role in estrogen-driven and GPR30 (zeige GPER Antikörper)-mediated endometrial carcinoma cell proliferation via the PTEN (zeige PTEN Antikörper)/PI3K (zeige PIK3CA Antikörper)/AKT (zeige AKT1 Antikörper) signaling pathway.

  6. ankyrin-B linker suppresses activity of the ANK (zeige ANK1 Antikörper) repeat domain through an intramolecular interaction, likely with a groove on the surface of the ANK (zeige ANK1 Antikörper) repeat solenoid, thereby regulating the affinities between ankyrin-B and its binding partners

  7. Residues 63-73 of cdB3 is also essential for ankyrin binding.

  8. Ankyrin-B protein (zeige LEPREL2 Antikörper) in heart failure: identification of a new component of metazoan cardioprotection.

  9. Reduced ankyrin-B expression or mutations in ankyrin 2 are associated with atrial fibrillation.

  10. Data show that DAnk2-binding is critical for beta spectrin function in vivo.

ANK2 Antigen-Profil

Beschreibung des Gens

This gene encodes a member of the ankyrin family of proteins that link the integral membrane proteins to the underlying spectrin-actin cytoskeleton. Ankyrins play key roles in activities such as cell motility, activation, proliferation, contact and the maintenance of specialized membrane domains. Most ankyrins are typically composed of three structural domains: an amino-terminal domain containing multiple ankyrin repeats\; a central region with a highly conserved spectrin binding domain\; and a carboxy-terminal regulatory domain which is the least conserved and subject to variation. The protein encoded by this gene is required for targeting and stability of Na/Ca exchanger 1 in cardiomyocytes. Mutations in this gene cause long QT syndrome 4 and cardiac arrhythmia syndrome. Multiple transcript variants encoding different isoforms have been described.

Alternative names and synonyms associated with ANK2

  • ankyrin 2, neuronal (ANK2) Antikörper
  • ankyrin 2b, neuronal (ank2b) Antikörper
  • ankyrin-2-like (LOC539238) Antikörper
  • ankyrin 2, neuronal (ank2) Antikörper
  • ankyrin repeat and zinc finger domain containing protein 1 (PTRG_09290) Antikörper
  • ankyrin 2, brain (Ank2) Antikörper
  • ankyrin 2, neuronal (Ank2) Antikörper
  • AI835472 Antikörper
  • ANK-2 Antikörper
  • ANK2 Antikörper
  • Ank3 Antikörper
  • ANKB Antikörper
  • AW491075 Antikörper
  • brank-2 Antikörper
  • CHANK2 Antikörper
  • LQT4 Antikörper
  • zgc:101738 Antikörper

Bezeichner auf Proteinebene für ANK2

ankyrin 2, neuronal , ankyrin-2-like , ankyrin repeat and zinc finger domain containing protein 1 , ankyrin-2 , ankyrin-B , brain ankyrin , ankyrin B , ankyrin, brain , ankyrin-2, nonerythrocytic , non-erythroid ankyrin , ankyrin 2, brain , ankyrin 3, epithelial

GENE ID SPEZIES
422689 Gallus gallus
450043 Danio rerio
461444 Pan troglodytes
539238 Bos taurus
100010497 Monodelphis domestica
100064198 Equus caballus
100076099 Ornithorhynchus anatinus
100176624 Ciona intestinalis
100436372 Pongo abelii
100465763 Ailuropoda melanoleuca
702180 Macaca mulatta
100512728 Sus scrofa
6347580 Pyrenophora tritici-repentis Pt-1C-BFP
109676 Mus musculus
287 Homo sapiens
362036 Rattus norvegicus
487908 Canis lupus familiaris
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