anti-Angiomotin (AMOT) Antikörper

Bezeichnung:
anti-Angiomotin Antikörper (AMOT)
Auf www.antikoerper-online.de finden Sie aktuell 98 Angiomotin (AMOT) Antikörper von 16 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Angiomotin Kits (24) und Angiomotin Proteine (5) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 139 Angiomotin Produkte verfügbar.
Synonyme:
AMOTL2, C81439, CAG-2, D0Kist1, E230009N18Rik, mKIAA1071, RGD1564027, si:dkey-13f9.6, Sii6, wu:fj21a07

Meistgesuchte Reaktivitäten zu anti-Angiomotin (AMOT) Antikörper

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anti-Human Angiomotin Antikörper:

anti-Mouse (Murine) Angiomotin Antikörper:

anti-Rat (Rattus) Angiomotin Antikörper:

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Am meisten referenzierte anti-Angiomotin Antikörper

  1. Human Polyclonal Angiomotin Primary Antibody für DB - ABIN1881054 : Heller, Adu-Gyamfi, Smith-Kinnaman, Babbey, Vora, Xue, Bittman, Stahelin, Wells: Amot recognizes a juxtanuclear endocytic recycling compartment via a novel lipid binding domain. in The Journal of biological chemistry 2010 (PubMed)
    Zeige alle 5 Referenzen für 1881054

  2. Human Polyclonal Angiomotin Primary Antibody für WB - ABIN531071 : Chan, Lim, Chong, Pobbati, Huang, Hong: Hippo pathway-independent restriction of TAZ and YAP by angiomotin. in The Journal of biological chemistry 2011 (PubMed)
    Zeige alle 2 Referenzen für 531071

  3. Human Polyclonal Angiomotin Primary Antibody für IF (p), IHC (p) - ABIN754873 : Shimada, Abe, Kohno, Satohisa, Konno, Takahashi, Hatakeyama, Arimoto, Kakuki, Kaneko, Takano, Saito, Kojima: Loss of tricellular tight junction protein LSR promotes cell invasion and migration via upregulation of TEAD1/AREG in human endometrial cancer. in Scientific reports 2017 (PubMed)

  4. Cow (Bovine) Polyclonal Angiomotin Primary Antibody für WB - ABIN2775938 : Holmgren, Ambrosino, Birot, Tullus, Veitonmäki, Levchenko, Carlson, Musiani, Iezzi, Curcio, Forni, Cavallo, Kiessling: A DNA vaccine targeting angiomotin inhibits angiogenesis and suppresses tumor growth. in Proceedings of the National Academy of Sciences of the United States of America 2006 (PubMed)

Weitere Antikörper gegen Angiomotin Interaktionspartner

Cow (Bovine) Angiomotin (AMOT) Interaktionspartner

  1. Amot and AmotL1 (zeige AMOTL1 Antikörper) have similar effects on endothelial migration and tight junction formation in vitro. In vivo Amot appears to control the cell polarity and AmotL1 (zeige AMOTL1 Antikörper) affects the stability of cell-cell junctions.

Zebrafish Angiomotin (AMOT) Interaktionspartner

  1. Thus AMOT is a direct substrate of Lats1 (zeige LATS1 Antikörper)/2 mediating functions of the Hippo pathway in endothelial cell migration and angiogenesis.

  2. knockdown of Amot reduced the number of filopodia of endoth (zeige PDPN Antikörper)elial tip cells and severely impaired the migration of intersegmental vessels

  3. Amot and AmotL1 (zeige AMOTL2 Antikörper) have similar effects on endothelial migration and tight junction formation in vitro. In vivo Amot appears to control the cell polarity and AmotL1 (zeige AMOTL2 Antikörper) affects the stability of cell-cell junctions.

Human Angiomotin (AMOT) Interaktionspartner

  1. AMOT may function as an oncogene (zeige RAB1A Antikörper) in the progression of colon cancer by activating the YAP (zeige YAP1 Antikörper)-ERK (zeige EPHB2 Antikörper)/PI3K (zeige PIK3CA Antikörper)-AKT (zeige AKT1 Antikörper) signaling pathway.

  2. The lncRNA SNHG12 promotes cell proliferation and migration by upregulating AMOT gene expression in osteosarcoma cells in vivo and in vitro.

  3. angiomotin and Merlin respectively interface cortical actin filaments and core kinases in Hippo signaling

  4. Study shows miR (zeige MLXIP Antikörper)-205 significantly downregulated and directly target the 3'-UTR (zeige UTS2R Antikörper) of AMOT in breast cancer. In vitro, miR (zeige MLXIP Antikörper)-205 regulates the proliferation and invasion of breast cancer cells through suppression of AMOT expression.

  5. Amot was highly expressed in breast cancer tissues and was important in the promotion of breast cancer cell proliferation and invasion. Amot knockdown in MCF-7 cells decreased the expression of YAP (zeige YAP1 Antikörper), YAP (zeige YAP1 Antikörper)/TAZ (zeige TAZ Antikörper) and LATS1 (zeige LATS1 Antikörper).

  6. experiments indicate that AMOT and other motin family members function together with NEDD4L (zeige NEDD4L Antikörper) to help complete immature virion assembly prior to ESCRT-mediated virus budding

  7. AMOT is a crucial suppressor of lung cancer metastasis and highlight its critical role as a tumor suppressor and its potential as a prognostic biomarker and therapeutic target for lung cancer.

  8. angiomotin proteins connect F-actin architecture to YAP (zeige YAP1 Antikörper) regulation.

  9. Scaffold proteins angiomotin (Amot) and angiomotin-related AmotL1 (zeige AMOTL1 Antikörper) and AmotL2 (zeige AMOTL2 Antikörper) were recently identified as negative regulators of YAP (zeige YAP1 Antikörper) and TAZ (zeige TAZ Antikörper) by preventing their nuclear translocation.

  10. Within the nucleus, Amot-p130 (zeige RBL2 Antikörper) was associated with the transcriptional complex containing Yap (zeige YAP1 Antikörper) and Teads (TEA domain family members) and contributed to the regulation of a subset of Yap (zeige YAP1 Antikörper) target genes, many of which are associated with tumorigenesis.

Mouse (Murine) Angiomotin (AMOT) Interaktionspartner

  1. a new function of RNF146 (zeige RNF146 Antikörper) and tankyrase in stabilizing the Crumbs complex through downregulation of AMOT proteins at the apical membrane, is reported.

  2. AMOT is a crucial suppressor of lung cancer metastasis and highlight its critical role as a tumor suppressor and its potential as a prognostic biomarker and therapeutic target for lung cancer.

  3. Within the nucleus, Amot-p130 was associated with the transcriptional complex containing Yap (zeige YAP1 Antikörper) and Teads (TEA domain family members) and contributed to the regulation of a subset of Yap (zeige YAP1 Antikörper) target genes, many of which are associated with tumorigenesis.

  4. The loss of Angiomotin, together with Angiomotin-like 2 (zeige AMOTL2 Antikörper), leads to differentiation of inner cell mass cells and compromised peri (zeige POSTN Antikörper)-implantation development.

  5. The phosphorylation of S176 in the N-terminal domain of Amot is a critical step for activation of the Hippo pathway in adherens junctions and cell polarity disconnects the Hippo pathway from cell-cell adhesion by sequestering Amot from AJs.

  6. Amot, Amotl1 (zeige AMOTL1 Antikörper), and Amotl2 (zeige AMOTL2 Antikörper) are differentially expressed in uterine cells during the peri (zeige POSTN Antikörper)-implantation period.

  7. A vaccine targeting angiomotin induces an antibody response which alters tumor vessel permeability and hampers the growth of established tumors.

  8. Depletion of Angiomotin in Nf2 (zeige NF2 Antikörper)(-/-) Schwann cells attenuates the Ras-MAPK (zeige MAPK1 Antikörper) signaling pathway, impedes cellular proliferation in vitro and tumorigenesis in vivo

  9. Angiomotin may promote neoplastic angiogenesis by both stimulating invasion as well as stabilizing established tubes.

  10. angiomotin, in addition to controlling cell motility, may play a role in the assembly of endothelial cell-cell junctions

Angiomotin (AMOT) Antigen-Profil

Beschreibung des Gens

This gene belongs to the motin family of angiostatin binding proteins characterized by conserved coiled-coil domains and C-terminal PDZ binding motifs. The encoded protein is expressed predominantly in endothelial cells of capillaries as well as larger vessels of the placenta where it may mediate the inhibitory effect of angiostatin on tube formation and the migration of endothelial cells toward growth factors during the formation of new blood vessels. Alternative splicing results in multiple transcript variants encoding different isoforms.

Alternative names and synonyms associated with Angiomotin (AMOT)

  • angiomotin (AMOT) Antikörper
  • angiomotin like 2 (AMOTL2) Antikörper
  • angiomotin (amot) Antikörper
  • angiomotin (Amot) Antikörper
  • AMOTL2 Antikörper
  • C81439 Antikörper
  • CAG-2 Antikörper
  • D0Kist1 Antikörper
  • E230009N18Rik Antikörper
  • mKIAA1071 Antikörper
  • RGD1564027 Antikörper
  • si:dkey-13f9.6 Antikörper
  • Sii6 Antikörper
  • wu:fj21a07 Antikörper

Bezeichner auf Proteinebene für anti-Angiomotin (AMOT) Antikörper

angiomotin like 2 , angiomotin-like protein 2 , angiomotin-like protein 2-like , angiomotin p130 isoform , angiomotin p80 isoform

GENE ID SPEZIES
100054069 Equus caballus
424863 Gallus gallus
485669 Canis lupus familiaris
538514 Bos taurus
563421 Danio rerio
100402195 Callithrix jacchus
422336 Gallus gallus
154796 Homo sapiens
481022 Canis lupus familiaris
27494 Mus musculus
300289 Rattus norvegicus
100158213 Sus scrofa
535509 Bos taurus
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