anti-NADPH Oxidase 4 (NOX4) Antikörper

anti-NADPH Oxidase 4 Antikörper (NOX4)
Auf finden Sie aktuell 182 NADPH Oxidase 4 (NOX4) Antikörper von 20 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen NADPH Oxidase 4 Kits (24) und NADPH Oxidase 4 Proteine (13) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 226 NADPH Oxidase 4 Produkte verfügbar.
AI648021, KOX, KOX-1, NOX4, RENOX

Meistgesuchte Reaktivitäten zu anti-NADPH Oxidase 4 (NOX4) Antikörper

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Am meisten referenzierte anti-NADPH Oxidase 4 Antikörper

  1. Cow (Bovine) Polyclonal NOX4 Primary Antibody für ICC, IHC (fro) - ABIN189715 : Maranchie, Zhan: Nox4 is critical for hypoxia-inducible factor 2-alpha transcriptional activity in von Hippel-Lindau-deficient renal cell carcinoma. in Cancer research 2005 (PubMed)
    Zeige alle 48 Referenzen für 189715

  2. Human Polyclonal NOX4 Primary Antibody für IHC (p), WB - ABIN657946 : Manea, Tanase, Raicu, Simionescu: Transcriptional regulation of NADPH oxidase isoforms, Nox1 and Nox4, by nuclear factor-kappaB in human aortic smooth muscle cells. in Biochemical and biophysical research communications 2010 (PubMed)
    Zeige alle 3 Referenzen für 657946

  3. Human Polyclonal NOX4 Primary Antibody für FACS, ICC - ABIN258606 : Basuroy, Bhattacharya, Leffler, Parfenova: Nox4 NADPH oxidase mediates oxidative stress and apoptosis caused by TNF-alpha in cerebral vascular endothelial cells. in American journal of physiology. Cell physiology 2009 (PubMed)
    Zeige alle 2 Referenzen für 258606

  4. Mouse (Murine) Polyclonal NOX4 Primary Antibody für IHC, WB - ABIN3023201 : Wingler, Wünsch, Kreutz, Rothermund, Paul, Schmidt: Upregulation of the vascular NAD(P)H-oxidase isoforms Nox1 and Nox4 by the renin-angiotensin system in vitro and in vivo. in Free radical biology & medicine 2001 (PubMed)

  5. Dog (Canine) Polyclonal NOX4 Primary Antibody für IF (p), IHC (p) - ABIN737526 : Khan, Byer, Khan: Exposure of Madin-Darby canine kidney (MDCK) cells to oxalate and calcium oxalate crystals activates nicotinamide adenine dinucleotide phosphate (NADPH)-oxidase. in Urology 2014 (PubMed)

  6. Human Polyclonal NOX4 Primary Antibody für IHC, IHC (p) - ABIN409683 : Zhang, Liu, Hu: Inhibiting cancer metastasis via targeting NAPDH oxidase 4. in Biochemical pharmacology 2013 (PubMed)

  7. Human Polyclonal NOX4 Primary Antibody für IF (p), IHC (p) - ABIN702610 : Kashiwabara, Ambe, Nakagawa, Watanabe: Immunohistochemical localization of Nox in mouse circumvallate papillae. in Tissue & cell 2015 (PubMed)

Weitere Antikörper gegen NADPH Oxidase 4 Interaktionspartner

Human NADPH Oxidase 4 (NOX4) Interaktionspartner

  1. data suggest that monocytic Nox4 is a central regulator of actin dynamics, and induction of Nox4 is the rate-limiting step in metabolic stress-induced monocyte priming and dysfunction associated with accelerated atherosclerosis and the progression of atherosclerotic plaques

  2. findings demonstrate that manipulation of the host PI3K (zeige PIK3CA Antikörper)/Akt (zeige AKT1 Antikörper) signaling pathway and Nox4 gene expression is a novel mechanism involved in T. gondii survival and proliferation

  3. Loss of NOX4 increases actomyosin levels and favours an epithelial to amoeboid transition contributing to tumour aggressiveness.

  4. NOX2 (zeige CYBB Antikörper), NOX4, and mitochondrial-derived reactive oxygen species contribute to angiopoietin-1 (zeige ANGPT1 Antikörper) signaling and angiogenic responses in endothelial cells.

  5. Mechanistically, HO-1 (zeige HMOX1 Antikörper) induction by all CRLPs requires NADPH oxidase 4, with PUFA-containing particles additionally dependent upon mitochondrial reactive oxygen species.These studies define new molecular pathways coupling endothelial cell activation by model CMRs with adaptive regulation of Nrf2 (zeige GABPA Antikörper)-dependent HO-1 (zeige HMOX1 Antikörper) expression

  6. NOX4 knockout cell lines showed reduced cell proliferation with an increase of sub-G1 cell population and the decrease of S/G2 (zeige STRN3 Antikörper)/M population, and resulted in a dramatic decrease in invadopodium formation and the invasive activity. NOX4 deficiency caused a decrease in focal adhesions and cell migration in HeLa cells. The results suggest that NOX4 is required for both efficient proliferation and invasion of HeLa cells.

  7. Thioredoxin (zeige TXN Antikörper) attenuates oxidized low-density lipoprotein induced oxidative stress in human umbilical vein endothelial cells by reducing NOX2 (zeige CYBB Antikörper)-NOX4 activity.

  8. Nox4-derived H2O2 in part activates Nox2 (zeige CYBB Antikörper) to increase mitochondrial ROS (zeige ROS1 Antikörper) via pSer36-p66Shc (zeige SHC1 Antikörper), thereby enhancing VEGFR2 (zeige KDR Antikörper) signaling and angiogenesis in endothelial cells.

  9. TGF-beta1 (zeige TGFB1 Antikörper) increases NADPH oxidase 4 (NOX4) mRNA and protein expression in normal human lung fibroblasts (NHLFs) and causes nuclear export of HDAC4 (zeige HDAC4 Antikörper).

  10. Nox4 should contribute to the pathological processes insubarachnoid hemorrhage(SAH (zeige ACSM3 Antikörper))-induced early brain injury (EBI (zeige TBL1X Antikörper)), and there was not an overlay effect of Nox2 (zeige CYBB Antikörper) inhibition and Nox4 inhibition on preventing SAH (zeige ACSM3 Antikörper)-induced EBI (zeige TBL1X Antikörper).

Cow (Bovine) NADPH Oxidase 4 (NOX4) Interaktionspartner

  1. Peroxide derived from superoxide generated by Nox4 appears to maintain a basal relaxation in bovine pulmonary arteries under normoxic conditions, which is removed under hypoxia leading to hypoxic pulmonary vasoconstriction.

Rabbit NADPH Oxidase 4 (NOX4) Interaktionspartner

  1. proteasome inhibition completely prevented endoplasmic reticulum stress-induced increase in NADPH oxidase (zeige NOX1 Antikörper) activity, as well as increases in Nox4 isoform and protein disulfide isomerase (zeige P4HB Antikörper) mRNA expression

Mouse (Murine) NADPH Oxidase 4 (NOX4) Interaktionspartner

  1. Nox2 (zeige CYBB Antikörper)- and Nox4-derived reactive oxygen species contribute to stem cell pluripotency maintenance and self-renewal.

  2. FYN (zeige FYN Antikörper) is activated by oxidative stress and serves as a negative feedback regulator of NOX4 in cardiomyocytes during cardiac remodeling

  3. NOX4-derived reactive oxygen species in general, and possibly superoxide in particular, are involved in flow-stimulated inner medullary collecting duct ET-1 (zeige EDN1 Antikörper) production.

  4. CYLD (zeige CYLD Antikörper) contributes to the transdifferentiation of adventitial fibroblasts via deubiquitinating Nox4 and may play a role in vascular remodeling.

  5. Data suggests that ROS (zeige ROS1 Antikörper) produced during primitive endoderm differentiation is dependent in part on increased NOX1 (zeige NOX1 Antikörper) and NOX4 levels, which is under the control of GATA6 (zeige GATA6 Antikörper). Furthermore, these results suggest that the combined activity of multiple NOX proteins is necessary for the differentiation of F9 cells to primitive endoderm.

  6. Nox4 is upregulated in pericytes in peri (zeige POSTN Antikörper)-infarct areas after acute brain ischemia and may enhance blood-brain barrier breakdown through activation of NFkappaB and matrix metalloproteinase 9 (zeige MMP9 Antikörper), thereby causing enlargement of infarct volume.

  7. Deficiency of NOX4 resulted in reduced expression of carnitine palmitoyltransferase 1A (CPT1A (zeige CPT1A Antikörper)), which is a key mitochondrial enzyme in the fatty acid oxidation (FAO) pathway. The reduced FAO resulted in less activation of the nucleotide-binding domain, leucine-rich-repeat-containing receptor (NLR (zeige CXCR5 Antikörper)), pyrin-domain-containing 3 (NLRP3 (zeige NLRP3 Antikörper)) inflammasome in macrophages.

  8. NOX4- and NOX1 (zeige NOX1 Antikörper)-derived ROS (zeige ROS1 Antikörper) contribute to atherosclerosis in the aortic sinus of diabetic ApoE (zeige APOE Antikörper) knockout mice.

  9. CD44V6 is part of a positive-feedback loop with TGFbeta1 (zeige TGFB1 Antikörper)/TGFbetaRI signaling that acts to increase NOX4/ROS (zeige ROS1 Antikörper) production, which is required for myofibroblast differentiation, myofibroblast differentiation, myofibroblast extracellular matrix production, myofibroblast invasion, and myofibroblast contractility.

  10. Nox4 mitigates cerebral artery structural changes in a murine model of Marfan syndrome.

Pig (Porcine) NADPH Oxidase 4 (NOX4) Interaktionspartner

  1. MRTF down-regulation/inhibition suppresses TGFbeta (zeige TGFB1 Antikörper)/contact disruption-provoked Nox4 protein and mRNA expression, Nox4 promoter activation, and reactive oxygen species production.

  2. Nox4 NADPH oxidase (zeige NOX1 Antikörper) mediates oxidative stress and apoptosis caused by TNF-alpha (zeige TNF Antikörper) in cerebral vascular endothelial cells.

  3. Nox4 NADPH oxidase (zeige NOX1 Antikörper)-derived reactive oxygen species also initiate a cell survival mechanism by increasing production of carbon monoxide by constitutive heme oxygenase-2 (zeige HMOX2 Antikörper).

NADPH Oxidase 4 (NOX4) Antigen-Profil

Beschreibung des Gens

This gene encodes a member of the NOX-family of enzymes that functions as the catalytic subunit the NADPH oxidase complex. The encoded protein is localized to non-phagocytic cells where it acts as an oxygen sensor and catalyzes the reduction of molecular oxygen to various reactive oxygen species (ROS). The ROS generated by this protein have been implicated in numerous biological functions including signal transduction, cell differentiation and tumor cell growth. A pseudogene has been identified on the other arm of chromosome 11. Alternative splicing results in multiple transcript variants.

Alternative names and synonyms associated with NADPH Oxidase 4 (NOX4)

  • NADPH oxidase 4 (NOX4) Antikörper
  • NADPH oxidase 4 (nox4) Antikörper
  • NADPH oxidase 4 (PTRG_09562) Antikörper
  • NADPH oxidase 4 (Nox4) Antikörper
  • AI648021 Antikörper
  • KOX Antikörper
  • KOX-1 Antikörper
  • NOX4 Antikörper
  • RENOX Antikörper

Bezeichner auf Proteinebene für anti-NADPH Oxidase 4 (NOX4) Antikörper

NADPH oxidase 4 , predicted NADPH oxidase-4 , kidney oxidase-1 , kidney superoxide-producing NADPH oxidase , renal NAD(P)H-oxidase , KOX-1 , superoxide-generating NADPH oxidase 4 , kox-1

419012 Gallus gallus
619226 Ciona intestinalis
705931 Macaca mulatta
735636 Pan troglodytes
6347852 Pyrenophora tritici-repentis Pt-1C-BFP
50507 Homo sapiens
378474 Bos taurus
100034665 Ovis aries
100339697 Oryctolagus cuniculus
50490 Mus musculus
85431 Rattus norvegicus
100523323 Sus scrofa
485144 Canis lupus familiaris
100171782 Pongo abelii
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