Use your antibodies-online credentials, if available.
Keine Produkte auf Ihrer Vergleichsliste.
Ihr Warenkorb ist leer.
Alle Spezies anzeigen
Weitere Synonyme anzeigen
Wählen Sie die Spezies und Applikation aus
anti-Rat (Rattus) Antikörper:
anti-Mouse (Murine) Antikörper:
Sie gelangen zu unserer vorgefilterten Suche.
Human Polyclonal TIMP2 Primary Antibody für IHC (p), ELISA - ABIN3044332
Xu, Ling, Zhu, Fan, Zhang: The effect of 2,3,4',5-tetrahydroxystilbene-2-0-?-D glucoside on neointima formation in a rat artery balloon injury model and its possible mechanisms. in European journal of pharmacology 2013
Show all 7 Pubmed References
Human Polyclonal TIMP2 Primary Antibody für WB - ABIN3043540
Jin, Jiang, Yang, Zhang, Yang, Zhang, Li, Yang, Ma: Acipimox attenuates atherosclerosis and enhances plaque stability in ApoE-deficient mice fed a palmitate-rich diet. in Biochemical and biophysical research communications 2012
Show all 7 Pubmed References
Human Polyclonal TIMP2 Primary Antibody für IF (p), IHC (p) - ABIN668346
Fang, Wu, Huang: Raloxifene upregulated mesangial cell MMP-2 activity via ER-? through transcriptional regulation. in Cell biochemistry and biophysics 2013
Show all 6 Pubmed References
Human Polyclonal TIMP2 Primary Antibody für IF, ELISA - ABIN1533420
Hu, Cai, Hu, Patel, Bard, Jamison, Coling: Metalloproteinases and their associated genes contribute to the functional integrity and noise-induced damage in the cochlear sensory epithelium. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2012
Show all 2 Pubmed References
Zebrafish Polyclonal TIMP2 Primary Antibody für ELISA - ABIN408743
Zhang, Bai, Tanase, Nagase, Sarras: The expression of tissue inhibitor of metalloproteinase 2 (TIMP-2) is required for normal development of zebrafish embryos. in Development genes and evolution 2003
Human Monoclonal TIMP2 Primary Antibody für IHC (p), IHC - ABIN449142
Chuang, Yeh, Yeh, Lin, Wang, Wang: Quercetin metabolites inhibit MMP-2 expression in A549 lung cancer cells by PPAR-γ associated mechanisms. in The Journal of nutritional biochemistry 2016
Human Polyclonal TIMP2 Primary Antibody für IHC (fro), IF - ABIN2476835
Mekhael, Bassily, Mekhael, Said: The response of adult rats to varying combinations of dietary lysine and threonine. in Die Nahrung 1991
Show all 2 Pubmed References
Human Monoclonal TIMP2 Primary Antibody für ELISA - ABIN2476833
Moses, Sudhalter, Langer: Identification of an inhibitor of neovascularization from cartilage. in Science (New York, N.Y.) 1990
Show all 4 Pubmed References
Suggest that IL-6 (zeige IL6 Antikörper) could promote the invasiveness of breast cancer cells by inducing secretion of TIMP-1 (zeige TIMP1 Antikörper) and -2, causing a disturbance in TIMP/MMP balance.
High TIMP2 expression is associated with acute kidney injury.
expression of TIMP2 was inversely associated with miR (zeige MLXIP Antikörper)-106a in nodule tissues. Apoptotic body was also seen under electron microscope accompanied by silencing of miR (zeige MLXIP Antikörper)-106a. Together, this data indicated that miR (zeige MLXIP Antikörper)-106a may act as an oncogene (zeige RAB1A Antikörper) and contribute to gastric cancer development.
Data show that the mean values for TIMP1 (zeige TIMP1 Antikörper), TIMP2 and MMP2 (zeige MMP2 Antikörper) were lower in survivors, MMP9 (zeige MMP9 Antikörper) was higher in survivors.
Urine [TIMP-2]*[IGFBP7 (zeige IGFBP7 Antikörper)] is a promising candidate for early detection of AKI, especially in ruling-out AKI
We conclude that in the resected esophageal cancer an increased mRNA expression of MMP-7 (zeige MMP7 Antikörper), MMP-10 (zeige MMP10 Antikörper) and TIMP-1 (zeige TIMP1 Antikörper) correlated with clinicopathologic features. We suggest that these genes may play a role during progression of the disease. MMP-10 (zeige MMP10 Antikörper), MMP-7 (zeige MMP7 Antikörper), TIMP-1 (zeige TIMP1 Antikörper), TIMP-2 were overexpressed in 73%, 85%, 55% and 42% of esophageal cancer samples, respectively.
At hospital admission, all viral gastroenteritis (GE) patients viral gastroenteritis (GE) patients demonstrated increased MMP-9 (zeige MMP9 Antikörper) and decreased MMP-2 (zeige MMP2 Antikörper) and TIMP-2 serum levels; kinetics of serum MMP-2 (zeige MMP2 Antikörper), MMP-9 (zeige MMP9 Antikörper), and TIMP-2 levels were similar among the viral GE patients but distinct from bacterial enteritis patients; involvement of MMPs and TIMPs in the pathophysiology of gastrointestinal symptoms likely varies depending on the
Meta-analysis indicated that urinary [TIMP-2].[IGFBP7 (zeige IGFBP7 Antikörper)] may be a reliable biomarker for the early detection of acute kidney injury in adults.
Results show that resistant hypertension was associated with higher TIMP-2 levels and low MMP-2 (zeige MMP2 Antikörper)/TIMP-2 ratio, suggesting that these regulators of ECM (zeige MMRN1 Antikörper) remodeling play a key role in blood pressure control in this high-risk subset of hypertensive individuals.
Data indicate the involvement of PKC-alpha (zeige PKCa Antikörper) in proMMP-2 activation and inhibition of TIMP-2 expression by NF-kappaB (zeige NFKB1 Antikörper)-MT1-MMP (zeige MMP14 Antikörper)-dependent and -independent pathway.
A differential pattern of matrix metalloproteinase-2 (zeige MMP2 Antikörper) and Tissue inhibitor metalloproteinase-2 was observed in cow uteri with adenomyosis.
MMP-14 (zeige MMP14 Antikörper), MMP-2 (zeige MMP2 Antikörper) and TIMP-2 are co-localized in the fetal compartment and therefore could influence the timely release of fetal membranes in cattle.
Results describe distinct changes in expression of MMP2 (zeige MMP2 Antikörper), MMP14 (zeige MMP14 Antikörper), and the metallopeptidase (zeige ECEL1 Antikörper) inhibitor TIMP2 between different phases of the estrous cycle indicating an endocrine regulation.
Production of TIMP-1 (zeige TIMP1 Antikörper) was augmented by IL-1alpha, TNFalpha (zeige TNF Antikörper), and hepatocyte growth factor (zeige HGF Antikörper) at level of translation and was transcriptionally increased by 12-O-tetradecanoylphorbol 13-acetate. Level of TIMP-2 mRNA was not affected by any treatments.
the different temporal expression patterns of TIMP-1 (zeige TIMP1 Antikörper) and TIMP-2 suggest that TIMP-1 (zeige TIMP1 Antikörper) may be important for luteal formation and development, while TIMP-2 may play significant roles during luteal development and maintenance
Identification, purification and partial characterization of timp-2 in bovine pulmonary artery smooth muscle
Results describe the isolation of matrix metalloproteinase 2 (MMP-2 (zeige MMP2 Antikörper)) from the MMP-2 (zeige MMP2 Antikörper)/tissue inhibitor of metalloproteinase 2 (TIMP-2) complex, and the characterization of both isolated MMP-2 (zeige MMP2 Antikörper) and the complex itself.
oxidants inactivate TIMP-2, and the resulting activation of MMP-2 (zeige MMP2 Antikörper) subsequently inhibits Na+ dependent Ca2 (zeige CA2 Antikörper)+ uptake in the microsomes
TIMP-2 has a role in the pericyte-induced stabilization of newly formed vascular networks that are predisposed to undergo regression and reveal specific molecular targets of the inhibitors regulating these events.
The pathology of laminitis is associated with increased and lowered transcription of MMP-14 (zeige MMP14 Antikörper) and TIMP-2, respectively.
the protein expression levels of TIMP-2 and PBEF (zeige NAMPT Antikörper) in cloned placentae, were examined.
demonstrate that TIMP-2 plays a greater protective role than TIMP-1 (zeige TIMP1 Antikörper) during the pathogenesis of atherosclerosis
Further investigation of MMP2 (zeige MMP2 Antikörper) inhibitors of TIMP2/TIMP4 (zeige TIMP4 Antikörper) showed an upregulated TIMP2 expression, but not TIMP4 (zeige TIMP4 Antikörper). low-dose pre-radiation attenuates the skin inflammation and ROS (zeige ROS1 Antikörper) production induced by medium-dose UV radiation
TIMP2 and TIMP3 (zeige TIMP3 Antikörper) play fundamental and differential roles in mediating pathological remodelling, independent from their MMP-inhibitory function
Reduced beta(2)GP I plays a role in diabetic mice related to vascular protection, inhibiting vascular lipid deposition, and plaque formation by reducing MMPs/TIMPs expression through down-regulation of the p38MAPK (zeige MAPK14 Antikörper) signaling pathway.
High TIMP2 expression is associated with liver fibrosis.
TIMP2 promotes kidney injury through metalloproteinase (MMP)2 (zeige MMP2 Antikörper) activation
Gene expression of Mmp-12 (zeige MMP12 Antikörper) and Mmp-13 (zeige MMP13 Antikörper), and Timp-1 (zeige TIMP1 Antikörper) was strongly upregulated at all time points in RD compared with controls. Timp-2, Mmp-2 (zeige MMP2 Antikörper), and Mmp-9 (zeige MMP9 Antikörper) expression was modest.
Data indicate a significantly increased expression of type I collagen, TIMP-2, TGF-beta (zeige TGFB1 Antikörper), PAI-1 (zeige SERPINE1 Antikörper) and RAGE (zeige AGER Antikörper) in diabetic db/db (zeige LEPR Antikörper) cells.
This study suggests that miR-17 participates in the regulation of cardiac matrix remodeling and provides a novel therapeutic approach using miR-17 inhibitors to prevent remodeling and heart failure after MI.
To further study the function of TIMP-2 in development, we utilized zebrafish as an experimental model system
membrane-type 1 metalloproteinase, gelatinase A (zeige MMP2 Antikörper) , and tissue inhibitor 2 of metalloproteinases mRNA transcripts were expressed in the blastema
This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix.
, metalloproteinase inhibitor 2
, tissue inhibitor of metalloproteinase 2
, tissue inhibitor of metalloproteinases 2
, collagenase inhibitor
, tissue inhibitor of mettaloproteinase 2
, tissue inhibitor of metalloproteinase-2
, tissue inhibitor of matrix metalloproteinase-2
, metalloproteinase inhibitor TIMP-2