Prostacyclin Receptor Proteine (PTGIR)

Bezeichnung:
Prostacyclin Receptor Proteine (PTGIR)
Auf www.antikoerper-online.de finden Sie aktuell 5 Prostacyclin Receptor (PTGIR) Proteine von 2 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Prostacyclin Receptor Antikörper (68) und Prostacyclin Receptor Kits (5) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 80 Prostacyclin Receptor Produkte verfügbar.
Synonyme:
IP, PGI2, PRIPR
alle Proteine anzeigen Gen GeneID UniProt
PTGIR 19222 P43252
PTGIR 5739 P43119
Ratte PTGIR PTGIR 292661 P43253

Weitere Synonyme anzeigen

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Weitere Proteine zu Prostacyclin Receptor Interaktionspartnern

Mouse (Murine) Prostacyclin Receptor (PTGIR) Interaktionspartner

  1. results provide evidence that PGI2/IP signaling suppresses the STAT6 (zeige STAT6 Proteine)-independent pathway of allergic airway inflammation

  2. Data (including data from studies using transgenic mice, an murine experimental model of diabetes, and mouse/human cell lines) suggest prostaglandin I2 receptor (Ptgir) is involved in insulin (zeige INS Proteine) secretion in pancreatic beta-cells and in permselectivity in glomerular podocytes; the mechanism appears to involve regulation of post-translational phosphorylation of nephrin (zeige NPHS1 Proteine).

  3. Deletion of the I prostanoid receptor had no effect on the attenuation of atherogenesis by mPGES-1 (zeige PTGES Proteine) deletion in the low-density lipoprotein receptor (zeige LDLR Proteine) knockout mice.

  4. Prostacyclin promotes the up-regulation of Nox4 (zeige NOX4 Proteine) in endothelial cells, which opens up a novel strategy that protects and enhances endothelial cell functions in cardiovascular disease, such as repair after myocardial infarction or other ischemic conditions.

  5. Its signaling increase cAMP concentration, which prototes sysnesis of HGF (zeige HGF Proteine), causing angiogenesis.

  6. an essential role of the COX-2/PGI2 receptor axis in the cardioprotection afforded by the late ischemic preconditioning

  7. findings suggest the IP receptor might maintain an angiogenic switch in the "on" state in tumor endothelial cells (TEC); suggest that the IP receptor is a TEC-specific marker and might be a useful therapeutic target

  8. PGI2-induced PPAR delta (zeige PPARD Proteine) activation accelerates blastocyst hatching in mice

  9. For the first time these results show that activation of prostaglandin I2 receptor can attenuate damage following cerebral ischemia.

  10. identify PGI(2)-prostaglandin I2 receptor as an important pathway for inhibiting allergic pulmonary inflammation by controlling recruitment of CD4 (zeige CD4 Proteine)(+) Th2 cells into the inflammatory site

Human Prostacyclin Receptor (PTGIR) Interaktionspartner

  1. role of IP-PPARdelta (zeige PPARD Proteine) signal transduction pathway in the production of sAPPalpha in cerebral microvasculature.

  2. Data (including data from studies using transgenic mice, an murine experimental model of diabetes, and mouse/human cell lines) suggest prostaglandin I2 receptor (PTGIR) is involved in insulin (zeige INS Proteine) secretion in pancreatic beta-cells and in permselectivity in glomerular podocytes; the mechanism appears to involve regulation of post-translational phosphorylation of nephrin (zeige NPHS1 Proteine).

  3. The human prostacyclin receptor gene is under the transcriptional regulation of dihydrotestosterone, where this regulation is further influenced by serum-cholesterol levels.

  4. these findings suggest that reduced IPR expression in DM2 (zeige CNBP Proteine) platelets may contribute to platelet hyperactivity in humans with type 2 diabetes.

  5. Prostaglandin I2- Prostaglandin I2 receptor signaling regulates human Th17 and Treg cell differentiation.

  6. these data provide critical insights into the transcriptional regulation of the human prostacyclin receptor gene within the vasculature, including during megakaryocytic differentiation

  7. IP receptor heteridimerization with thromboxane receptor (zeige TBXA2R Proteine) facilitates receptor trafficking to membrane lipid rafts.

  8. Prostacyclin receptor-dependent inhibition of human erythroleukemia cell differentiation is STAT3 (zeige STAT3 Proteine)-dependent

  9. IKEPP (zeige PDZD3 Proteine) was also found to be expressed in vascular endothelial cells where it co-localizes and complexes with the hIP

  10. the IP receptor was expressed in blood vessels of renal cell carcinoma specimens, but not in glomerular vessels of normal renal tissue; findings suggest the IP receptor might maintain an angiogenic switch in the "on" state in tumor endothelial cells (TEC); suggest that the IP receptor is a TEC-specific marker and might be a useful therapeutic target

Prostacyclin Receptor (PTGIR) Protein Überblick

Protein Überblick

The protein encoded by this gene is a member of the G-protein coupled receptor family 1 and has been shown to be a receptor for prostacyclin. Prostacyclin, the major product of cyclooxygenase in macrovascular endothelium, elicits a potent vasodilation and inhibition of platelet aggregation through binding to this receptor.

Alternative names and synonyms associated with Prostacyclin Receptor (PTGIR)

  • prostaglandin I receptor (IP) (Ptgir)
  • prostaglandin I2 (prostacyclin) receptor (IP) (PTGIR)
  • prostaglandin I2 (prostacyclin) receptor (IP) (Ptgir)
  • IP Protein
  • PGI2 Protein
  • PRIPR Protein

Bezeichner auf Proteinebene für Prostacyclin Receptor Proteine (PTGIR)

PGI receptor , PGI2 receptor , prostacyclin receptor , prostaglandin I2 receptor , prostanoid IP receptor , prostaglandin I receptor (IP)

GENE ID SPEZIES
19222 Mus musculus
5739 Homo sapiens
292661 Rattus norvegicus
520278 Bos taurus
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