anti-MC2R (MC2R) Antikörper

anti-Melanocortin 2 Receptor (Adrenocorticotropic Hormone) Antikörper (MC2R)
Auf finden Sie aktuell 74 Melanocortin 2 Receptor (Adrenocorticotropic Hormone) (MC2R) Antikörper von 16 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen MC2R Kits (32) und und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 114 MC2R Produkte verfügbar.

Meistgesuchte Reaktivitäten zu anti-MC2R (MC2R) Antikörper

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anti-Rat (Rattus) MC2R Antikörper:

anti-Mouse (Murine) MC2R Antikörper:

anti-Human MC2R Antikörper:

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Am meisten referenzierte anti-MC2R Antikörper

  1. Human Polyclonal MC2R Primary Antibody für FACS, IHC (p) - ABIN651731 : Roy, Perron, Gallo-Payet: Role of asparagine-linked glycosylation in cell surface expression and function of the human adrenocorticotropin receptor (melanocortin 2 receptor) in 293/FRT cells. in Endocrinology 2010 (PubMed)
    Zeige alle 2 Referenzen für 651731

  2. Human Polyclonal MC2R Primary Antibody für ELISA, WB - ABIN238653 : Kilianova, Basora, Kilian, Payet, Gallo-Payet: Human melanocortin receptor 2 expression and functionality: effects of protein kinase A and protein kinase C on desensitization and internalization. in Endocrinology 2006 (PubMed)

  3. Rat (Rattus) Polyclonal MC2R Primary Antibody für IHC, WB - ABIN1742044 : Gantz, Fong: The melanocortin system. in American journal of physiology. Endocrinology and metabolism 2003 (PubMed)

  4. Human Polyclonal MC2R Primary Antibody für IF, ELISA - ABIN1535648 : Mountjoy, Robbins, Mortrud, Cone: The cloning of a family of genes that encode the melanocortin receptors. in Science (New York, N.Y.) 1992 (PubMed)

Weitere Antikörper gegen MC2R Interaktionspartner

Zebrafish Melanocortin 2 Receptor (Adrenocorticotropic Hormone) (MC2R) Interaktionspartner

  1. zfMC2R is not functional in the absence of MRAP expression.

Rainbow Trout (Oncorhynchus mykiss) Melanocortin 2 Receptor (Adrenocorticotropic Hormone) (MC2R) Interaktionspartner

  1. Data suggest enzymes in steroidogenic pathway are induced in interrenal cells during acute/chronic stress: MC2R (melanocortin 2 receptor); StAR (steroidogenic acute regulatory protein (zeige STAR Antikörper)); 3beta-hydroxysteroid dehydrogenase; steroid 11beta hydroxylase.

  2. Rainbow trout melanocortin-2 receptor structure and function analysis.

  3. ACTH (zeige POMC Antikörper) regulation of MC2R is highly conserved in vertebrates.

Mouse (Murine) Melanocortin 2 Receptor (Adrenocorticotropic Hormone) (MC2R) Interaktionspartner

  1. JDP2 (zeige JDP2 Antikörper) acts as a novel transcriptional activator of the mouse Mc2r gene, suggesting that JDP2 (zeige JDP2 Antikörper) may have physiological functions as a novel player in MC2R-mediated steroidogenesis as well as cell signaling in adrenal glands.

  2. Data show that neuromedin B (NMB) expression was higher in the melanocortin 2 receptor MC2R(-/-) than in the wild-type (WT) mice.

  3. MC2R plays an important role for regular lipolytic function and lipid composition in 3T3-L1 adipocytes.

  4. melanocortin 2 receptor and melanocortin 5 receptor (zeige MC5R Antikörper) are lipolytic mediators in differentiated 3T3-L1 adipocytes

  5. MC2R+/- pups delivered from MC2R-/- females crossed with MC2R+/+ males mice thrived poorly with MC2R-/- mothers but grew to adulthood when transferred to foster mothers after birth, suggesting that MC2R-/- females are poor mothers or cannot nurse.

  6. The promoter activity of Mc2r is activated by FOXL2 (zeige FOXL2 Antikörper) in a dose-dependent manner; transcriptional activity of Mc2r is up-regulated by synergistic interaction of FOXL2 (zeige FOXL2 Antikörper) and NR5A1 (zeige NR5A1 Antikörper).

  7. Data show that melanocortins regulate Il6 (zeige IL6 Antikörper) gene expression and production in 3T3-L1 adipocytes through melanocortin receptors 2 and 5.

  8. MC2R in Y1 cells internalizes by a G protein coupled receptor (zeige GPR34 Antikörper) kinase dependent clathrin-coated pit (zeige IRF6 Antikörper) mechanism.

  9. Data show that adrenocorticotrophic hormone resistance in tumor cell mutants is associated with a base change polymorphism in the steroidogenic factor 1 (zeige NR5A1 Antikörper) gene.

  10. Novel 135-bp exon 1f of ACTH-R gene was located 1.4 kb downstream in genome of exon 1a transcribed in adrenal gland. Promoter region flanking to exon 1f may be essential for adipose tissue; that flanking to exon 1a is specific for the adrenal gland.

Human Melanocortin 2 Receptor (Adrenocorticotropic Hormone) (MC2R) Interaktionspartner

  1. Results show regulation of melanocortin receptors MC2R, MC3R (zeige MC3R Antikörper) and MC4R (zeige MC4R Antikörper) gene expressions in CD8 (zeige CD8A Antikörper)(+) cytotoxic T-lymphocytes and CD19 (zeige CD19 Antikörper)(+) B lymphocytes in rheumatoid arthritis (RA) treated with tumor necrosis factor-alpha (TNF-alpha (zeige TNF Antikörper)) inhibitor (zeige ZFP36 Antikörper) adalimumab.

  2. Four rare missense variants were identified (ACTBL2 (zeige ACTBL2 Antikörper) rs73757391 (5q11.2), BTD (zeige BTD Antikörper) rs200337373 (3p25.1), KRT13 (zeige KRT13 Antikörper) rs150321809 (17q21.2) and MC2R rs104894658 (18p11.21)), but only MC2R rs104894668 had a large effect size (OR = 9.66).

  3. melanocortin receptors MC2R, MC3R (zeige MC3R Antikörper) and MC5R (zeige MC5R Antikörper) are most abundantly expressed in glandular epithelium of the endometrium

  4. MC2R and MC1R (zeige MSHR Antikörper) signals are consecutively required for the regulation of EPO (zeige EPO Antikörper) signal transduction in erythroblast differentiation, and MC5R (zeige MC5R Antikörper) signal transduction is required to induce enucleation.

  5. the MC2R gene may contribute to the development of intracerebral hemorrhage.

  6. The A allele at rs1941088 in the MC2R gene, which encodes the adrenocorticotropic hormone (corticotropin, ACTH) receptor, is associated with a low cortisol response in critically ill children.

  7. results suggest that Phe(7) in ACTH (zeige POMC Antikörper) plays an important role in ligand selectivity and that the third transmembrane domain of MC2R is crucial for ACTH (zeige POMC Antikörper) selectivity and potency

  8. MC2R overexpression is associated with myelolipomas.

  9. The patient with familial glucocorticoid deficiency was found to be homozygous for a novel mutation in the melanocortin-2 receptor gene (635insC, I154H).

  10. Our observations suggest that MC2R is involved in prostate carcinogenesis and that targeting MC2R signaling may provide a novel avenue in prostate carcinoma treatment.

MC2R Antigen-Profil

Beschreibung des Gens

MC2R encodes one member of the five-member G-protein associated melanocortin receptor family. Melanocortins (melanocyte-stimulating hormones and adrenocorticotropic hormone) are peptides derived from pro-opiomelanocortin (POMC). MC2R is selectively activated by adrenocorticotropic hormone, whereas the other four melanocortin receptors recognize a variety of melanocortin ligands. Mutations in MC2R can result in familial glucocorticoid deficiency.

Alternative names and synonyms associated with MC2R

  • melanocortin 2 receptor (adrenocorticotropic hormone) (MC2R) Antikörper
  • adrenocorticotropic hormone receptor (ACTHR) Antikörper
  • melanocortin 2 receptor (adrenocorticotropic hormone) (Mc2r) Antikörper
  • melanocortin 2 receptor (mc2r) Antikörper
  • melanocortin 2 receptor (LOC100222030) Antikörper
  • adrenocorticotropic hormone receptor-like (LOC100739231) Antikörper
  • adrenocorticotropic hormone receptor-like (LOC100855756) Antikörper
  • melanocortin 2 receptor (Mc2r) Antikörper
  • ACTH-R Antikörper
  • ACTHR Antikörper
  • MC2 Antikörper
  • MC2-R Antikörper
  • MC2R Antikörper

Bezeichner auf Proteinebene für MC2R

melanocortin 2 receptor (adrenocorticotropic hormone) , adrenocorticotropic hormone receptor , melanocortin 2 receptor , G-protein-coupled receptor , melanocortin 2 receptor-like , putative melanocortin 2 receptor , ACTH receptor , Adrenocorticotropin receptor , Melanocortin receptor 2 , adrenocorticotropin receptor , melanocortin receptor 2 , ACTH-R , ACTH-receptor , MC2 receptor , corticotropin receptor , MC2-R , melanocortin 2 receptor (adrenocorticotropic hormone receptor) , adrenal ACTH receptor , melanocortin 2-receptor

397427 Sus scrofa
483980 Canis lupus familiaris
692350 Felis catus
282839 Rattus norvegicus
353152 Danio rerio
445998 Takifugu rubripes
100136719 Oncorhynchus mykiss
100222030 Taeniopygia guttata
100739231 Sus scrofa
100855756 Canis lupus familiaris
17200 Mus musculus
100135574 Cavia porcellus
4158 Homo sapiens
281299 Bos taurus
443482 Ovis aries
428516 Gallus gallus
101825745 Mesocricetus auratus
Ausgewählte Anbieter für anti-MC2R (MC2R) Antikörper
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