anti-CCR2 (CCR2) Antikörper

Bezeichnung:
anti-Chemokine (C-C Motif) Receptor 2 Antikörper (CCR2)
Auf www.antikoerper-online.de finden Sie aktuell 302 Chemokine (C-C Motif) Receptor 2 (CCR2) Antikörper von 24 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen CCR2 Kits (15) und CCR2 Proteine (5) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 331 CCR2 Produkte verfügbar.
Synonyme:
Cc-ckr-2, CCR-2, Ccr2a, Ccr2b, CD192, Ckr2, Ckr2a, Ckr2b, Cmkbr2, MCP-1-R, mJe-r

Alle verfügbaren anti-CCR2 Antikörper

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Am meisten referenzierte anti-CCR2 Antikörper

  1. Human Monoclonal CCR2 Primary Antibody für FACS - ABIN4895495 : Tsujioka, Imanishi, Ikejima, Kuroi, Takarada, Tanimoto, Kitabata, Okochi, Arita, Ishibashi, Komukai, Kataiwa, Nakamura, Hirata, Tanaka, Akasaka: Impact of heterogeneity of human peripheral blood monocyte subsets on myocardial salvage in patients with primary acute myocardial infarction. in Journal of the American College of Cardiology 2009 (PubMed)
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  2. Human Monoclonal CCR2 Primary Antibody für FACS, IHC - ABIN4899089 : Manley, Caso, Works, Cutler, Zemlyak, Sun, Munhoz, Chang, Sorrells, Ermini, Decker, Bertrand, Dinkel, Steinberg, Sapolsky: Derivation of injury-responsive dendritic cells for acute brain targeting and therapeutic protein delivery in the stroke-injured rat. in PLoS ONE 2013 (PubMed)
    Zeige alle 22 Referenzen für 4899089

  3. Human Monoclonal CCR2 Primary Antibody für FACS - ABIN4895486 : Shantsila, Wrigley, Tapp, Apostolakis, Montoro-Garcia, Drayson, Lip: Immunophenotypic characterization of human monocyte subsets: possible implications for cardiovascular disease pathophysiology. in Journal of thrombosis and haemostasis : JTH 2011 (PubMed)
    Zeige alle 8 Referenzen für 4895486

  4. Mouse (Murine) Monoclonal CCR2 Primary Antibody für FACS - ABIN4898197 : Levy, Milikovsky, Baranauskas, Vinogradov, David, Ketzef, Abutbul, Weissberg, Kamintsky, Fleidervish, Friedman, Monsonego: Differential TGF-β Signaling in Glial Subsets Underlies IL-6-Mediated Epileptogenesis in Mice. in Journal of immunology (Baltimore, Md. : 1950) 2015 (PubMed)
    Zeige alle 6 Referenzen für 4898197

  5. Human Monoclonal CCR2 Primary Antibody für FACS - ABIN4895488 : Dagouassat, Suffee, Hlawaty, Haddad, Charni, Laguillier, Vassy, Martin, Schischmanoff, Gattegno, Oudar, Sutton, Charnaux: Monocyte chemoattractant protein-1 (MCP-1)/CCL2 secreted by hepatic myofibroblasts promotes migration and invasion of human hepatoma cells. in International journal of cancer 2010 (PubMed)
    Zeige alle 5 Referenzen für 4895488

  6. Human Monoclonal CCR2 Primary Antibody für FACS - ABIN4895489 : Campanelli, Fois, Catarsi, Poletto, Villani, Erba, Maddaluno, Jemos, Salmoiraghi, Guglielmelli, Abbonante, Di Buduo, Balduini, Iurlo, Barosi, Rosti, Massa: Tie2 Expressing Monocytes in the Spleen of Patients with Primary Myelofibrosis. in PLoS ONE 2016 (PubMed)
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  7. Human Polyclonal CCR2 Primary Antibody für WB - ABIN2787666 : Hendrickson, Jacobson, Nelson, Phair, Lautenberger, Johnson, Kingsley, Margolick, Detels, Goedert, OBrien: Host genetic influences on highly active antiretroviral therapy efficacy and AIDS-free survival. in Journal of acquired immune deficiency syndromes (1999) 2008 (PubMed)
    Zeige alle 2 Referenzen für 2787666

  8. Human Monoclonal CCR2 Primary Antibody für FACS - ABIN4895491 : Kanabar, Tedaldi, Jiang, Nie, Panina, Descroix, Man, Pitchford, Page, Wagner: Base-modified UDP-sugars reduce cell surface levels of P-selectin glycoprotein 1 (PSGL-1) on IL-1β-stimulated human monocytes. in Glycobiology 2016 (PubMed)
    Zeige alle 2 Referenzen für 4895491

  9. Human Monoclonal CCR2 Primary Antibody für FACS - ABIN4895493 : Falk, Singh, Faber, Nissen, Hviid, Sørensen: CX3CL1/CX3CR1 and CCL2/CCR2 chemokine/chemokine receptor complex in patients with AMD. in PLoS ONE 2014 (PubMed)

  10. Human Polyclonal CCR2 Primary Antibody für FACS, IHC (p) - ABIN152124 : Menasria, Canivet, Piret, Gosselin, Boivin: Both Cerebral and Hematopoietic Deficiencies in CCR2 Result in Uncontrolled Herpes Simplex Virus Infection of the Central Nervous System in Mice. in PLoS ONE 2016 (PubMed)

Weitere Antikörper gegen CCR2 Interaktionspartner

Human Chemokine (C-C Motif) Receptor 2 (CCR2) Interaktionspartner

  1. The CCR2 (+190 G/A) GG genotype frequencies for patients were significantly higher in the stage III-IV cancer group ( p = 0.036), and A allele carriers were significantly higher in the stage I-II ovarian cancer group.

  2. tumor-promoting role for CCL2 acting through CCR2 on the tumor microenvironment

  3. The findings of the work indicate a role for Galphaq (zeige GNAQ Antikörper) and/or Galpha14 and in CCR2a/CCR2b-stimulated Rho A (zeige RHOA Antikörper) GTPase (zeige RACGAP1 Antikörper)-mediated serum response factor activation.

  4. Endogenous TRAIL/TRAIL-R-mediated CCL2 (zeige CCL2 Antikörper) secretion promotes accumulation of tumor-supportive immune cells in the cancer microenvironment.

  5. CCL2 (zeige CCL2 Antikörper)/CCR2 axis is expressed in the majority of monocytoid Acute myeloid leukemia (zeige BCL11A Antikörper) blasts

  6. CCR2B and beta2AR (zeige ADRB2 Antikörper) signals to FLNa (zeige FLNA Antikörper) to stimulate its endocytosis and recycling to the plasma membrane.

  7. this study shows that CYTL1 (zeige CYTL1 Antikörper) possesses chemotactic activity and demonstrates that its functional receptor is CCR2B

  8. PCSK9 regulates monocyte CCR2 expression and chemotaxis.

  9. CCR2-targeted therapy with PF-04136309 in combination with FOLFIRINOX is safe and tolerable

  10. Binding of J113863 to CCR2 or CCR5 also induced the recruitment of beta-arrestin 2, whereas UCB35625 did not. UCB35625 induced the chemotaxis of L1.2 cells expressing CCR2 or CCR5. In contrast, J113863 induced the migration of L1.2-CCR2 cells but antagonized the chemokine-induced migration of L1.2-CCR5 cells.

Mouse (Murine) Chemokine (C-C Motif) Receptor 2 (CCR2) Interaktionspartner

  1. in vitro and in vivo results show that CCR2 intrinsically mediates the expression of inflammatory T cell cytokines, and its absence on T cells results in attenuated colitis progression

  2. tumor-promoting role for CCL2 acting through CCR2 on the tumor microenvironment

  3. CCR2 expression on bone marrow-derived cells, likely macrophages, is essential to muscle regeneration independent of TLR signaling, aging, and sex.

  4. we demonstrated that CX3CR1 (zeige CX3CR1 Antikörper)(Lo)CCR2(Hi) monocytes were recruited to the GBM, where they transitioned to CX3CR1 (zeige CX3CR1 Antikörper)(Hi)CCR2(Lo) macrophages and CX3CR1 (zeige CX3CR1 Antikörper)(Hi)CCR2(-) microglia-like cells. Infiltrating macrophages/monocytes constituted approximately 85% of the total TAM (zeige CCNA1 Antikörper) population, with resident microglia accounting for the approximately 15% remaining.

  5. we characterized a novel regulatory network in macrophages, in which CCR2 activates PI3K-AKT (zeige AKT1 Antikörper)-mTOR (zeige FRAP1 Antikörper) signaling to mediate HIF-1alpha (zeige HIF1A Antikörper) expression, which then drives VEGF-C (zeige VEGFC Antikörper) expression to promote lymphangiogenesis.

  6. CXCR4 (zeige CXCR4 Antikörper), CCR2, and CX3CR1 (zeige CX3CR1 Antikörper) direct dendritic cell precursors from the bone marrow to the lung differentially.

  7. The findings suggest that CCR2 deficiency does not provide a sustained benefit and that Ly6C(low) macrophages may contribute to the progressive fibrosis and dysfunction of mdx (zeige DMD Antikörper)(5cv) diaphragm.

  8. In Ccr2(-/-) mice, a damaged microglia recruitment was shown in retina and this could protect the visual function in electroretinogram and alleviate the photoreceptor apoptosis.

  9. This study establishes ECL1i as the first allosteric inhibitor of CCR2 with functional selectivity.

  10. the individual and combined actions of CCL2 (zeige CCL2 Antikörper)/CCR2 and CX3CL1 (zeige CX3CL1 Antikörper)/CX3CR1 (zeige CX3CR1 Antikörper) in hypoxia-induced pulmonary hypertension in mice, is reported.

CCR2 Antigen-Profil

Beschreibung des Gens

This gene encodes two isoforms of a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The receptors encoded by this gene mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This gene is located in the chemokine receptor gene cluster region. Two alternatively spliced transcript variants are expressed by the gene.

Alternative names and synonyms associated with CCR2

  • chemokine (C-C motif) receptor 2 (CCR2) Antikörper
  • chemokine (C-C motif) receptor 2 (Ccr2) Antikörper
  • Cc-ckr-2 Antikörper
  • CCR-2 Antikörper
  • Ccr2a Antikörper
  • Ccr2b Antikörper
  • CD192 Antikörper
  • Ckr2 Antikörper
  • Ckr2a Antikörper
  • Ckr2b Antikörper
  • Cmkbr2 Antikörper
  • MCP-1-R Antikörper
  • mJe-r Antikörper

Bezeichner auf Proteinebene für CCR2

C-C chemokine receptor type 2 , MCP-1 receptor , monocyte chemoattractant protein 1 receptor , monocyte chemotactic protein 1 receptor , C-C CHEMOKINE RECEPTOR TYPE 2 (C-C CKR-2) (CC-CKR-2) (CCR-2) (CCR2) (JE/FIC RECEPTOR) (MCP-1 RECEPTOR) , C-C CKR-2 , CCR-2 , JE/FIC receptor , MIP-1 alphaR , chemoattractant protein-1 receptor , chemokine (C-C) receptor 2 , CC-CKR-2 , chemokine receptor CCR2 , MCP-1-R , chemokine receptor

GENE ID SPEZIES
729230 Homo sapiens
12772 Mus musculus
60463 Rattus norvegicus
484790 Canis lupus familiaris
574098 Macaca mulatta
Ausgewählte Anbieter für anti-CCR2 (CCR2) Antikörper
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