beta 2 Adrenergic Receptor Proteine (ADRB2)

Bezeichnung:
Adrenergic, beta-2-, Receptor, Surface Proteine (ADRB2)
Auf www.antikoerper-online.de finden Sie aktuell 4 Adrenergic, beta-2-, Receptor, Surface (ADRB2) Proteine von 2 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen beta 2 Adrenergic Receptor Antikörper (276) und beta 2 Adrenergic Receptor Kits (43) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 342 beta 2 Adrenergic Receptor Produkte verfügbar.
Synonyme:
Adrb-2, adrb2, ADRB2R, ADRBR, B2AR, Badm, BAR, BETA2AR, Gpcr7, zgc:162188
alle Proteine anzeigen Gen GeneID UniProt
ADRB2 11555 P18762
ADRB2 154 P07550
Ratte ADRB2 ADRB2 24176  

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Weitere Proteine zu beta 2 Adrenergic Receptor Interaktionspartnern

Zebrafish Adrenergic, beta-2-, Receptor, Surface (ADRB2) Interaktionspartner

  1. Zebrafish larvae lacking beta1AR (zeige ADRB1 Proteine) expression by morpholino knockdown displayed lower heart rates than control fish, whereas larvae deficient in both beta2aAR and beta2bAR expression exhibited significantly higher heart rates than controls.

Mouse (Murine) Adrenergic, beta-2-, Receptor, Surface (ADRB2) Interaktionspartner

  1. Together, these data indicate that high-fat diet promotes phosphorylation of the beta2 AR, contributing to impairment of cardiac contractile reserve before cardiac structural and functional remodelling, suggesting that early intervention in the insulin (zeige INS Proteine)-adrenergic signalling network might be effective in prevention of cardiac complications in diabetes

  2. beta2-AR deletion is associated to selective hepatic insulin (zeige INS Proteine) resistance and preserved skeletal muscle insulin (zeige INS Proteine) sensitivity.

  3. The diurnal variation of the humoral immune response was dependent on beta2AR-mediated neural signals and was diminished when lymphocyte recirculation through lymph nodes was stopped.

  4. knocking out of the beta1/2 (zeige TFAP2B Proteine) receptor significantly diminished the ST25 acupuncture-induced inhibition of gastric motility and jejunal motility without significantly altering the enhancement of colonic motility induced by acupuncture at ST25.

  5. The authors show that phosphorylation of S1928 displaces the beta-2 adrenergic receptor from Cav1.2 (zeige CACNA1C Proteine) upon beta-adrenergic stimulation rendering Cav1.2 (zeige CACNA1C Proteine) refractory for several minutes from further beta-adrenergic stimulation.

  6. The Galphas (zeige GNAS Proteine) and Galphaq (zeige GNAQ Proteine) peptides adopt different orientations in beta2-AR and V1AR (zeige AVPR1A Proteine), respectively. The beta2-AR/Galphas (zeige GNAS Proteine) peptide interface is dominated by electrostatic interactions, whereas the V1AR (zeige AVPR1A Proteine)/Galphaq (zeige GNAQ Proteine) peptide interactions are predominantly hydrophobic.

  7. Thus the beta2AR acts as a double-edged sword: increasing TAS2R14 cell surface expression, but when activated by beta-agonist, partially offsetting the expression phenotype by direct receptor:receptor desensitization of TAS2R14 function.

  8. Data show that inhibitory (Galphai2 (zeige GNAI2 Proteine)) and stimulatory (GalphasL) G-protein subunits produced minor atrophic and hypertrophic changes in muscle mass, and Galphai2 (zeige GNAI2 Proteine) over-expression prevented AAV:beta2-adrenoceptor (beta2-AR) mediated hypertrophy.

  9. Immune cell-expressed beta2AR plays an essential role in regulating the early inflammatory repair response to acute myocardial injury by facilitating cardiac leukocyte infiltration.

  10. In epileptic seizures mouse model, Pkdl (zeige PKD2L1 Proteine) deficiency leads to the loss of beta2AR on neuronal cilia, reduction in cAMP levels in the central nervous system, and reduction in the activation of cAMP response element-binding protein.

Cow (Bovine) Adrenergic, beta-2-, Receptor, Surface (ADRB2) Interaktionspartner

  1. These results indicate dependence of hepatic glucocorticoid and adrenergic receptors on stage of maturation in neonatal calves and emphasize the association of alpha1-adrenergic receptor and glucocorticoid receptor (zeige NR3C1 Proteine) with neonatal glucose and lipid metabolism.

  2. ADRb2 shows lipid scrambling activity.

  3. relationship between luteal concentrations of oxytocin (OT), noradrenaline (NA), progesterone (P4), oxytocin receptors (OT-R (zeige OXTR Proteine)) and beta(2)-adrenoreceptors (beta(2)-R) gene expression and their protein level throughout the estrous cycle

Human Adrenergic, beta-2-, Receptor, Surface (ADRB2) Interaktionspartner

  1. The frequency of the genotypes and alleles of rs1042711 in ADRB2 showed a significant difference between the COPD (zeige ARCN1 Proteine) and control groups. TT genotype and TG and TC haplotypes of rs1042711 in ADRB2 are related to pulmonary function in COPD (zeige ARCN1 Proteine) patients. TT genotype of rs1042711 in ADRB2 and smoking amount are risk factors for COPD (zeige ARCN1 Proteine) development.

  2. Results provide further evidence for the interaction of rs2400707, and other SNPs within the ADRB2 gene, with childhood trauma in relation to risk for posttraumatic stress disorder.

  3. Gln27Glu polymorphism of ADRB2 influences exercise-induced vascular adaptation in patients with acute coronary syndrome.

  4. Data suggest that ADRB2 (beta2 adrenergic receptor) activation (as illustrated by epinephrine and nor epinephrine) leads to robust calcium ion mobilization from intracellular stores in endoplasmic reticulum via activation of phosphoinositide phospholipase C (PLC) and opening of inositol trisphosphate receptor (IP3R).

  5. Data suggest that post-translational modifications (phosphorylation, oxidation, and nitrosylation) of RyR2 (ryanodine receptor 2) occur downstream of production of amyloid beta-peptides through ADRB2 (beta2-adrenergic receptor) Ca2 (zeige CA2 Proteine)+ signaling cascade that activates PKA (protein kinase A).

  6. ADRB2 SNPs might be a genetic risk factor for dyslipidemia in the Chinese hypertensive patients. the A46G polymorphism was significantly associated with the elevated risk of hypertriglyceridemia. Haplotype analysis showed that the TAC (zeige IL2RA Proteine) haplotype carrying frequent alleles of the three SNPs played a reduced role in hypertriglyceridemia risk and the TGC (zeige TGM2 Proteine) haplotype carrying rare allele of A46G expressed a significant risk effe

  7. The beta2-adrenergic receptor, which induces a short cAMP response, prolongs nuclear cAMP and protein kinase A (PKA) activation by promoting endosomal cAMP production in parathyroid hormone (PTH (zeige PTH Proteine)) receptor signaling through the stimulatory action of G protein Gbetagamma subunits on adenylate cyclase type 2 (zeige ADCY2 Proteine).

  8. beta2AR S-palmitoylated at Cys (zeige DNAJC5 Proteine)-265 are selectively preserved under a sustained adrenergic stimulation, which results in the down-regulation and degradation of betaAR.

  9. The Galphas (zeige GNAS Proteine) and Galphaq (zeige GNAQ Proteine) peptides adopt different orientations in beta2-AR and V1AR (zeige AVPR1A Proteine), respectively. The beta2-AR/Galphas (zeige GNAS Proteine) peptide interface is dominated by electrostatic interactions, whereas the V1AR (zeige AVPR1A Proteine)/Galphaq (zeige GNAQ Proteine) peptide interactions are predominantly hydrophobic.

  10. Thus the beta2AR acts as a double-edged sword: increasing TAS2R14 (zeige TAS2R14 Proteine) cell surface expression, but when activated by beta-agonist, partially offsetting the expression phenotype by direct receptor:receptor desensitization of TAS2R14 (zeige TAS2R14 Proteine) function.

Pig (Porcine) Adrenergic, beta-2-, Receptor, Surface (ADRB2) Interaktionspartner

  1. The Galphas (zeige GNAS Proteine) and Galphaq (zeige GNAQ Proteine) peptides adopt different orientations in beta2-AR and V1AR (zeige AVPR1A Proteine), respectively. The beta2-AR/Galphas (zeige GNAS Proteine) peptide interface is dominated by electrostatic interactions, whereas the V1AR (zeige AVPR1A Proteine)/Galphaq (zeige GNAQ Proteine) peptide interactions are predominantly hydrophobic.

  2. A persistent B2R (zeige BDKRB2 Proteine)-beta2AR heterodimer was confirmed in bradykinin-stimulated and non-stimulated left ventricular myocardium. BK transactivation of beta2AR enhanced beta2AR-mediated release of tPA (zeige PLAT Proteine).

  3. Prolactin (zeige PRL Proteine) infusion brought about the inhibition of a vasodilatory beta(2)-adrenergic receptor-mediated effect related to the NO intracellular pathway

  4. Intracoronary intermedin (zeige ADM2 Proteine) 1-47 augments cardiac perfusion and function in anesthetized pigs: role of calcitonin (zeige CALCA Proteine) receptors and beta-adrenoreceptor-mediated nitric oxide release.

Rhesus Monkey Adrenergic, beta-2-, Receptor, Surface (ADRB2) Interaktionspartner

  1. The results imply ADRB-2-mediated actions in the development of primate follicles

beta 2 Adrenergic Receptor (ADRB2) Protein Überblick

Protein Überblick

This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes.

Alternative names and synonyms associated with beta 2 Adrenergic Receptor (ADRB2)

  • adrenoceptor beta 2, surface (ADRB2)
  • adrenergic receptor, beta 2b (adrb2b)
  • beta2-adrenergic receptor (LOC100136153)
  • adrenergic receptor, beta 2 (Adrb2)
  • adrenergic, beta-2-, receptor, surface (ADRB2)
  • adrenoceptor beta 2, surface (Adrb2)
  • Adrb-2 Protein
  • adrb2 Protein
  • ADRB2R Protein
  • ADRBR Protein
  • B2AR Protein
  • Badm Protein
  • BAR Protein
  • BETA2AR Protein
  • Gpcr7 Protein
  • zgc:162188 Protein

Bezeichner auf Proteinebene für ADRB2

adrenergic receptor beta-2 , adrenergic, beta-2-, receptor, surface , beta-2 adrenergic receptor , beta-2b-adrenergic receptor , beta-2 adrenoceptor , beta-2 adrenoreceptor , beta 2-AR , adrenergic receptor beta 2 , adrenergic, beta-2, receptor, surface , catecholamine receptor , beta2-adrenergic receptor , Adrenergic beta 2- receptor surface , adrenergic receptor, beta 2 , Beta-2 adrenergic receptor , Beta-2 adrenoceptor , Beta-2 adrenoreceptor , beta 2 adrenergic receptor , beta-2-adrenergic receptor

GENE ID SPEZIES
100170320 Ovis aries
100060659 Equus caballus
100037315 Danio rerio
100136153 Oncorhynchus mykiss
11555 Mus musculus
281605 Bos taurus
154 Homo sapiens
403910 Canis lupus familiaris
24176 Rattus norvegicus
493767 Felis catus
100722663 Cavia porcellus
397357 Sus scrofa
471690 Pan troglodytes
101836719 Mesocricetus auratus
710146 Macaca mulatta
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