anti-BNIP3 (BNIP3) Antikörper

Bezeichnung:
anti-BCL2/adenovirus E1B 19kDa Interacting Protein 3 Antikörper (BNIP3)
Auf www.antikoerper-online.de finden Sie aktuell 166 BCL2/adenovirus E1B 19kDa Interacting Protein 3 (BNIP3) Antikörper von 17 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen BNIP3 Kits (12) und BNIP3 Proteine (5) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 192 BNIP3 Produkte verfügbar.
Synonyme:
Nip3
Alle Antikörper anzeigen Gen GeneID UniProt
BNIP3 664 Q12983
BNIP3 12176 O55003
BNIP3 84480  

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anti-Human BNIP3 Antikörper:

anti-Mouse (Murine) BNIP3 Antikörper:

anti-Rat (Rattus) BNIP3 Antikörper:

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Am meisten referenzierte anti-BNIP3 Antikörper

  1. Human Polyclonal BNIP3 Primary Antibody für IF, IHC (p) - ABIN388117 : Kothari, Cizeau, McMillan-Ward, Israels, Bailes, Ens, Kirshenbaum, Gibson: BNIP3 plays a role in hypoxic cell death in human epithelial cells that is inhibited by growth factors EGF and IGF. in Oncogene 2003 (PubMed)
    Zeige alle 5 Referenzen für 388117

  2. Human Monoclonal BNIP3 Primary Antibody für ICC, IF - ABIN151087 : Landes, Emorine, Courilleau, Rojo, Belenguer, Arnauné-Pelloquin: The BH3-only Bnip3 binds to the dynamin Opa1 to promote mitochondrial fragmentation and apoptosis by distinct mechanisms. in EMBO reports 2010 (PubMed)
    Zeige alle 2 Referenzen für 151087

  3. Human Polyclonal BNIP3 Primary Antibody für EIA, IHC (p) - ABIN356828 : Zhang, Heim, Meyhack: Novel BNIP1 variants and their interaction with BCL2 family members. in FEBS letters 1999 (PubMed)
    Zeige alle 2 Referenzen für 356828

  4. Human Polyclonal BNIP3 Primary Antibody für ICC, IF - ABIN4284980 : Yang, Yang, Guo, Williams, Weissler: PLAGL2 expression-induced lung epithelium damages at bronchiolar alveolar duct junction in emphysema: bNip3- and SP-C-associated cell death/injury activity. in American journal of physiology. Lung cellular and molecular physiology 2009 (PubMed)

Weitere Antikörper gegen BNIP3 Interaktionspartner

Human BCL2/adenovirus E1B 19kDa Interacting Protein 3 (BNIP3) Interaktionspartner

  1. the results suggest that BNIP3 plays a vital role in regulating PINK1 (zeige PINK1 Antikörper) mitochondrial outer membrane localization, the proteolytic process of PINK1 (zeige PINK1 Antikörper) and PINK1 (zeige PINK1 Antikörper)/parkin (zeige PARK2 Antikörper)-mediated mitophagy under physiological conditions.

  2. High BNIP3 expression is associated with chronic myelogenous leukemia.

  3. Results suggest that changes in mitochondrial morphology and transmembrane potential, induced by mutant htt (zeige HTT Antikörper) protein, are dependent and linked to BNip3 and not to Bax (zeige BAX Antikörper)/Bak (zeige BAK1 Antikörper) activation.

  4. Hypoxia-induced autophagy contributes to the invasion of salivary adenoid cystic carcinoma through the HIF-1alpha (zeige HIF1A Antikörper)/BNIP3 signaling pathway.

  5. The data indicated that BNIP3 plays a vital role in the tumorigenesis of adenoid cystic carcinoma and could be a new target for gene therapy of adenoid cystic carcinoma.

  6. BNIP3 deletion can be used as a prognostic (zeige HIF1A Antikörper)marker of tumor progression to metastasis in human triple-negative breast cancer

  7. BNIP3 expression was found to be regulated by Sp3 (zeige SP3 Antikörper) in prostate cancer.

  8. phosphorylation of these C-terminal BNIP3 residues blocks cell death without preventing autophagy, providing evidence that the two functional roles of BNIP3 can be regulated independently

  9. Bnip3 dual-functionality and crosstalk between mitophagy and apoptosis pathways is presented here.

  10. these findings revealed that silibinin induced autophagic cell death through ROS (zeige ROS1 Antikörper)-dependent mitochondrial dysfunction and ATP depletion involving BNIP3 in MCF7 cells.

Mouse (Murine) BCL2/adenovirus E1B 19kDa Interacting Protein 3 (BNIP3) Interaktionspartner

  1. In a neuronal model of dominant optic atrophy, BNIP3 down-regulation reduced autophagy and mitophagy.

  2. Down-regulation of Bcl2/adenovirus E1B 19-kDa-interacting protein 3 (BNIP3) by olomoucine, a cyclin (zeige PCNA Antikörper)-dependent kinasesinhibitor, reduces lipopolysaccharide - and nitric oxide-induced cell death in BV2 (zeige DNAH9 Antikörper) microglial cells. Olomoucine may protect cells by limiting proinflammatory responses, thereby reducing nitric oxide generation.

  3. data outline Bnip3 as a key effector of PPARgamma (zeige PPARG Antikörper)-mediated adipose mitochondrial network fragmentation, improving insulin (zeige INS Antikörper) sensitivity and limiting oxidative stress.

  4. the results suggest that BNIP3 plays a vital role in regulating PINK1 (zeige PINK1 Antikörper) mitochondrial outer membrane localization, the proteolytic process of PINK1 (zeige PINK1 Antikörper) and PINK1 (zeige PINK1 Antikörper)/parkin (zeige PARK2 Antikörper)-mediated mitophagy under physiological conditions.

  5. BNIP3 interacts with the mitochondrial outer membrane directly via mitochondrial BAX (zeige BAX Antikörper).

  6. Data show that TGFbeta (zeige TGFB1 Antikörper)-activated kinase-1 (TAK1 (zeige NR2C2 Antikörper)) activated nuclear factor of activated T-cells (NFAT (zeige NFATC1 Antikörper))/NF-kappa B (NFkappaB (zeige NFKB1 Antikörper)), downregulated BCL2-adenovirus E1B interacting protein 3 (Bnip3), and inhibited cardiac cell death.

  7. propose that BNIP3 acts as a brake on HIF-1 (zeige HIF1A Antikörper) activity serving to increase rates of mitophagy in response to hypoxia and to limit production of damaging ROS (zeige ROS1 Antikörper) that would further amplify HIF-1 (zeige HIF1A Antikörper) expression and promote tumor progression to metastasis

  8. Results suggest that Bnip3 regulates cardiac gene expression and perhaps myocyte morphology by activating nuclear p300 acetyltransferase and hyperacetylating histones and its selective transcription factors.

  9. Bnip3 dual-functionality and crosstalk between mitophagy and apoptosis pathways is presented here.

  10. regulates mitophagy during hypoxia, whereas NIX (zeige BNIP3L Antikörper) is required for mitophagy during development of the erythroid lineage.

BNIP3 Antigen-Profil

Beschreibung des Gens

This gene is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. It interacts with the E1B 19 kDa protein, which protects cells from virally-induced cell death. The encoded protein also interacts with E1B 19 kDa-like sequences of BCL2, another apoptotic protector. This protein contains a BH3 domain and a transmembrane domain, which have been associated with pro-apoptotic function. The dimeric mitochondrial protein encoded by this gene is known to induce apoptosis, even in the presence of BCL2.

Alternative names and synonyms associated with BNIP3

  • BCL2/adenovirus E1B 19kDa interacting protein 3 (BNIP3) Antikörper
  • BCL2/adenovirus E1B interacting protein 3 (Bnip3) Antikörper
  • Nip3 Antikörper

Bezeichner auf Proteinebene für BNIP3

BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 , BCL2/adenovirus E1B 19kD-interacting protein 3 , BCL2/adenovirus E1B 19 kDa-interacting protein 1, NIP3 , BCL2/adenovirus E1B 19kDa-interacting protein 1, NIP3 , BCL2/adenovirus E1B interacting protein 1, NIP3 , BCL2/adenovirus E1B 19 kDa-interacting protein 3

GENE ID SPEZIES
664 Homo sapiens
423971 Gallus gallus
607408 Canis lupus familiaris
615342 Bos taurus
12176 Mus musculus
84480 Rattus norvegicus
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